THROMKIDplus Patient Registry and Biomaterial Banking for Children with Inherited Platelet Disorders
Hamostaseologie. 2023 Nov 2. doi: 10.1055/a-2117-4639. Online ahead of print.ABSTRACTInherited platelet disorders (IPDs) represent a heterogeneous group of disorders that include both quantitative (thrombocytopenia or thrombocytosis) and qualitative (thrombocytopathy) defects. To gain better knowledge about the prevalence, pathogenesis, and clinical consequences of specific diseases, to improve diagnosis and treatment of patients with IPD, and to support translational research on a genetic, molecular, and physiological basis, the THROMKIDplus study group currently comprising 24 sites in Germany, Austria, and Switzerland de...
Source: Hamostaseologie - November 2, 2023 Category: Hematology Authors: Matthias Ballmaier Manuela Germeshausen Harald Schulze Oliver Andres THROMKIDplus Study Group Source Type: research
THROMKIDplus Patient Registry and Biomaterial Banking for Children with Inherited Platelet Disorders
Hamostaseologie. 2023 Nov 2. doi: 10.1055/a-2117-4639. Online ahead of print.ABSTRACTInherited platelet disorders (IPDs) represent a heterogeneous group of disorders that include both quantitative (thrombocytopenia or thrombocytosis) and qualitative (thrombocytopathy) defects. To gain better knowledge about the prevalence, pathogenesis, and clinical consequences of specific diseases, to improve diagnosis and treatment of patients with IPD, and to support translational research on a genetic, molecular, and physiological basis, the THROMKIDplus study group currently comprising 24 sites in Germany, Austria, and Switzerland de...
Source: Hamostaseologie - November 2, 2023 Category: Hematology Authors: Matthias Ballmaier Manuela Germeshausen Harald Schulze Oliver Andres THROMKIDplus Study Group Source Type: research
THROMKIDplus Patient Registry and Biomaterial Banking for Children with Inherited Platelet Disorders
Hamostaseologie. 2023 Nov 2. doi: 10.1055/a-2117-4639. Online ahead of print.ABSTRACTInherited platelet disorders (IPDs) represent a heterogeneous group of disorders that include both quantitative (thrombocytopenia or thrombocytosis) and qualitative (thrombocytopathy) defects. To gain better knowledge about the prevalence, pathogenesis, and clinical consequences of specific diseases, to improve diagnosis and treatment of patients with IPD, and to support translational research on a genetic, molecular, and physiological basis, the THROMKIDplus study group currently comprising 24 sites in Germany, Austria, and Switzerland de...
Source: Hamostaseologie - November 2, 2023 Category: Hematology Authors: Matthias Ballmaier Manuela Germeshausen Harald Schulze Oliver Andres THROMKIDplus Study Group Source Type: research
THROMKIDplus Patient Registry and Biomaterial Banking for Children with Inherited Platelet Disorders
Hamostaseologie. 2023 Nov 2. doi: 10.1055/a-2117-4639. Online ahead of print.ABSTRACTInherited platelet disorders (IPDs) represent a heterogeneous group of disorders that include both quantitative (thrombocytopenia or thrombocytosis) and qualitative (thrombocytopathy) defects. To gain better knowledge about the prevalence, pathogenesis, and clinical consequences of specific diseases, to improve diagnosis and treatment of patients with IPD, and to support translational research on a genetic, molecular, and physiological basis, the THROMKIDplus study group currently comprising 24 sites in Germany, Austria, and Switzerland de...
Source: Hamostaseologie - November 2, 2023 Category: Hematology Authors: Matthias Ballmaier Manuela Germeshausen Harald Schulze Oliver Andres THROMKIDplus Study Group Source Type: research
THROMKIDplus Patient Registry and Biomaterial Banking for Children with Inherited Platelet Disorders
Hamostaseologie. 2023 Nov 2. doi: 10.1055/a-2117-4639. Online ahead of print.ABSTRACTInherited platelet disorders (IPDs) represent a heterogeneous group of disorders that include both quantitative (thrombocytopenia or thrombocytosis) and qualitative (thrombocytopathy) defects. To gain better knowledge about the prevalence, pathogenesis, and clinical consequences of specific diseases, to improve diagnosis and treatment of patients with IPD, and to support translational research on a genetic, molecular, and physiological basis, the THROMKIDplus study group currently comprising 24 sites in Germany, Austria, and Switzerland de...
Source: Hamostaseologie - November 2, 2023 Category: Hematology Authors: Matthias Ballmaier Manuela Germeshausen Harald Schulze Oliver Andres THROMKIDplus Study Group Source Type: research
THROMKIDplus Patient Registry and Biomaterial Banking for Children with Inherited Platelet Disorders
Hamostaseologie. 2023 Nov 2. doi: 10.1055/a-2117-4639. Online ahead of print.ABSTRACTInherited platelet disorders (IPDs) represent a heterogeneous group of disorders that include both quantitative (thrombocytopenia or thrombocytosis) and qualitative (thrombocytopathy) defects. To gain better knowledge about the prevalence, pathogenesis, and clinical consequences of specific diseases, to improve diagnosis and treatment of patients with IPD, and to support translational research on a genetic, molecular, and physiological basis, the THROMKIDplus study group currently comprising 24 sites in Germany, Austria, and Switzerland de...
Source: Hamostaseologie - November 2, 2023 Category: Hematology Authors: Matthias Ballmaier Manuela Germeshausen Harald Schulze Oliver Andres THROMKIDplus Study Group Source Type: research
Management of Recurrent Venous Thromboembolism in Severe Immune Thrombocytopenia: A Case Report and a Review of the Literature
We report a case of a 58-year-old man with recurrent unprovoked deep vein thrombosis (DVT) and severe immune thrombocytopenia (ITP) with a platelet count of 19 × 109/L. We further review studies reporting venous thromboembolism (VTE) in patients with severe ITP (≤ 35 × 109/L) and identified 14 patients highlighting VTE risk factors and management of these patients. The present case had several risk factors for VTE (previous DVT, obesity, heterozygosity for factor V Leiden mutation, and previous splenectomy). The patient was initially treated with low-molecular-weight heparin followed by long-term apixaban treatment. Th...
Source: Hamostaseologie - October 31, 2023 Category: Hematology Authors: Mathias Haargaard Nielsen Mustafa Vakur Bor Source Type: research
Management of Recurrent Venous Thromboembolism in Severe Immune Thrombocytopenia: A Case Report and a Review of the Literature
We report a case of a 58-year-old man with recurrent unprovoked deep vein thrombosis (DVT) and severe immune thrombocytopenia (ITP) with a platelet count of 19 × 109/L. We further review studies reporting venous thromboembolism (VTE) in patients with severe ITP (≤ 35 × 109/L) and identified 14 patients highlighting VTE risk factors and management of these patients. The present case had several risk factors for VTE (previous DVT, obesity, heterozygosity for factor V Leiden mutation, and previous splenectomy). The patient was initially treated with low-molecular-weight heparin followed by long-term apixaban treatment. Th...
Source: Hamostaseologie - October 31, 2023 Category: Hematology Authors: Mathias Haargaard Nielsen Mustafa Vakur Bor Source Type: research
Mobilization and Hematopoietic Stem Cell Collection in Poor Mobilizing Patients with Lymphoma: Final Results of the German OPTIMOB Study
CONCLUSIONS: Majority of PM patients with lymphoma were successfully mobilized and underwent ASCT. Most of them received PLX during the study.PMID:37899991 | PMC:PMC10601601 | DOI:10.1159/000531936 (Source: Hamostaseologie)
Source: Hamostaseologie - October 30, 2023 Category: Hematology Authors: Katharina Kriegsmann Max Bittrich Sandra Sauer Carola Tietze-Stolley Kamran Movassaghi Matthias Grube Vladan Vucinic Daniela Wehler Andreas Burchert Martin Schmidt-Hieber Andreas Rank Heinz A D ürk Bernd Metzner Christoph Kimmich Marcus Hentrich Christia Source Type: research
Preexisting Chronic Thromboembolic Pulmonary Hypertension in Acute Pulmonary Embolism? A Case Report and Discussion
Hamostaseologie. 2023 Oct 30. doi: 10.1055/a-2173-7712. Online ahead of print.ABSTRACTA 61-year-old male presented with New York Heart Association class II breathlessness. Three years earlier, he had presented with a swollen leg, had received a diagnosis of deep vein thrombosis on ultrasound and of low-risk acute pulmonary embolism, and had been discharged on a direct oral anticoagulant after 8 hours. The patient also had a history of thyroidectomy and was on levothyroxine substitution. The case illustrates a patient with acute pulmonary embolism who developed chronic thrombotic pulmonary vascular lesions within 3 years af...
Source: Hamostaseologie - October 30, 2023 Category: Hematology Authors: Irene M Lang Marion Delcroix Source Type: research
Mobilization and Hematopoietic Stem Cell Collection in Poor Mobilizing Patients with Lymphoma: Final Results of the German OPTIMOB Study
CONCLUSIONS: Majority of PM patients with lymphoma were successfully mobilized and underwent ASCT. Most of them received PLX during the study.PMID:37899991 | PMC:PMC10601601 | DOI:10.1159/000531936 (Source: Hamostaseologie)
Source: Hamostaseologie - October 30, 2023 Category: Hematology Authors: Katharina Kriegsmann Max Bittrich Sandra Sauer Carola Tietze-Stolley Kamran Movassaghi Matthias Grube Vladan Vucinic Daniela Wehler Andreas Burchert Martin Schmidt-Hieber Andreas Rank Heinz A D ürk Bernd Metzner Christoph Kimmich Marcus Hentrich Christia Source Type: research
Preexisting Chronic Thromboembolic Pulmonary Hypertension in Acute Pulmonary Embolism? A Case Report and Discussion
Hamostaseologie. 2023 Oct 30. doi: 10.1055/a-2173-7712. Online ahead of print.ABSTRACTA 61-year-old male presented with New York Heart Association class II breathlessness. Three years earlier, he had presented with a swollen leg, had received a diagnosis of deep vein thrombosis on ultrasound and of low-risk acute pulmonary embolism, and had been discharged on a direct oral anticoagulant after 8 hours. The patient also had a history of thyroidectomy and was on levothyroxine substitution. The case illustrates a patient with acute pulmonary embolism who developed chronic thrombotic pulmonary vascular lesions within 3 years af...
Source: Hamostaseologie - October 30, 2023 Category: Hematology Authors: Irene M Lang Marion Delcroix Source Type: research
Mobilization and Hematopoietic Stem Cell Collection in Poor Mobilizing Patients with Lymphoma: Final Results of the German OPTIMOB Study
CONCLUSIONS: Majority of PM patients with lymphoma were successfully mobilized and underwent ASCT. Most of them received PLX during the study.PMID:37899991 | PMC:PMC10601601 | DOI:10.1159/000531936 (Source: Hamostaseologie)
Source: Hamostaseologie - October 30, 2023 Category: Hematology Authors: Katharina Kriegsmann Max Bittrich Sandra Sauer Carola Tietze-Stolley Kamran Movassaghi Matthias Grube Vladan Vucinic Daniela Wehler Andreas Burchert Martin Schmidt-Hieber Andreas Rank Heinz A D ürk Bernd Metzner Christoph Kimmich Marcus Hentrich Christia Source Type: research
Subsegmental Pulmonary Embolism
Hamostaseologie. 2023 Oct 23. doi: 10.1055/a-2163-3111. Online ahead of print.ABSTRACTSubsegmental pulmonary embolism (SSPE) is increasingly diagnosed with the growing use and technological advancements of multidetector computed tomography pulmonary angiography. Its diagnosis is challenging, and some presumed SSPE may actually represent imaging artifacts. Indirect evidence and results from small observational studies suggest that SSPE may be more benign than more proximal pulmonary embolism, and may thus not always require treatment. Therefore, guidelines suggest to consider a management strategy without anticoagulation in...
Source: Hamostaseologie - October 23, 2023 Category: Hematology Authors: Christine Baumgartner Tobias Tritschler Drahomir Aujesky Source Type: research
Subsegmental Pulmonary Embolism
Hamostaseologie. 2023 Oct 23. doi: 10.1055/a-2163-3111. Online ahead of print.ABSTRACTSubsegmental pulmonary embolism (SSPE) is increasingly diagnosed with the growing use and technological advancements of multidetector computed tomography pulmonary angiography. Its diagnosis is challenging, and some presumed SSPE may actually represent imaging artifacts. Indirect evidence and results from small observational studies suggest that SSPE may be more benign than more proximal pulmonary embolism, and may thus not always require treatment. Therefore, guidelines suggest to consider a management strategy without anticoagulation in...
Source: Hamostaseologie - October 23, 2023 Category: Hematology Authors: Christine Baumgartner Tobias Tritschler Drahomir Aujesky Source Type: research
