Postexposure prophylaxis after bite of a broad-winged bat with evidence of European bat lyssavirus 1 (EBLV-1)
We report on a patient who suffered a bat bite in an urban setting in which European bat lyssavirus 1 (EBLV-1) was detected in the euthanized bat. We performed active and passive postexposure prophylaxis (PEP). This case study illustrates the ongoing risk of rabies infection due to close bat contacts in Germany and is intended to sensitize primary care physicians to take such exposure events seriously and to perform a regular PEP including administration of rabies immunoglobulin.PMID:38100072 | DOI:10.1007/s00108-023-01638-3 (Source: Hamostaseologie)
Source: Hamostaseologie - December 15, 2023 Category: Hematology Authors: Jannik Fasse Henning Trawinski Michael Hardt Christoph L übbert Source Type: research
Potenzielle globale Gerinnungsparameter f ür Therapiemonitoring unter Emicizumab
Hamostaseologie. 2023 Dec;43(6):394. doi: 10.1055/s-0043-1777816. Epub 2023 Dec 14.ABSTRACTWäHREND DIE BEHANDLUNG DER GENETISCH BEDINGTEN GERINNUNGSSTöRUNG HäMOPHILIE A IN DER VERGANGENHEIT IN REGELMäßIGEN INTRAVENöSEN FAKTOR-VIII-INFUSIONEN BESTAND, STEHT HEUTE MIT DEM ANTIKöRPER EMICIZUMAB EINE EFFEKTIVE ALTERNATIVE ZUR SUBKUTANEN APPLIKATION ZUR VERFüGUNG. BISHER FEHLEN ALLERDINGS PARAMETER, MIT DENEN SICH DAS AUSMAß DER GERINNUNGSKORREKTUR BEIM EINZELNEN PATIENTEN VERLäSSLICH ABBILDEN LäSST. IN EINER AKTUELLEN STUDIE KRISTALLISIERTEN SICH JETZT ZWEI GLOBALE GERINNUNGSPARAMETER HERAUS, MIT DENEN EIN SOLCHES M...
Source: Hamostaseologie - December 14, 2023 Category: Hematology Source Type: research
Marker der Akute-Phase-Reaktion k önnten Blutungen bei Hämophilie detektieren
Hamostaseologie. 2023 Dec;43(6):396. doi: 10.1055/s-0043-1777817. Epub 2023 Dec 14.ABSTRACTBEI DER HäMOPHILIE A UND B WERDEN IM RAHMEN VON AKUTEN HäMORRHAGIEN ENTZüNDUNGSREAKTIONEN AUSGELöST. SIND GELENKE VON DEN BLUTUNGEN BETROFFEN, KANN HIERAUS DIE SO GENANNTE HäMOPHILE ARTHROPATHIE RESULTIEREN. IN EINER AKTUELLEN STUDIE WURDEN JETZT PATIENTEN MIT HäMOPHILIE IM HINBLICK AUF MARKER DER AKUTE-PHASE-REAKTION UNTERSUCHT. DARüBER HINAUS WURDE EIN TIERMODELL ETABLIERT.PMID:38096833 | DOI:10.1055/s-0043-1777817 (Source: Hamostaseologie)
Source: Hamostaseologie - December 14, 2023 Category: Hematology Source Type: research
GTH News
Hamostaseologie. 2023 Dec;43(6):449-453. doi: 10.1055/s-0043-1777814. Epub 2023 Dec 14.NO ABSTRACTPMID:38096834 | DOI:10.1055/s-0043-1777814 (Source: Hamostaseologie)
Source: Hamostaseologie - December 14, 2023 Category: Hematology Source Type: research
Programm f ür die Veranstaltung des BDDH im Rahmen der 68. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung in Wien 2024 und Petition an den Deutschen Bundestag aufgrund eines drohenden Praxenkollaps
Hamostaseologie. 2023 Dec;43(6):454-455. doi: 10.1055/a-2031-8165. Epub 2023 Dec 14.NO ABSTRACTPMID:38096835 | DOI:10.1055/a-2031-8165 (Source: Hamostaseologie)
Source: Hamostaseologie - December 14, 2023 Category: Hematology Authors: J ürgen Koscielny G ünther Kappert Christoph Sucker Source Type: research
Erratum: A Novel Fibrinogen Mutation p.B βAla68Asp Causes an Inherited Dysfibrinogenemia
Hamostaseologie. 2023 Dec;43(6):e1. doi: 10.1055/a-2218-6919. Epub 2023 Dec 14.NO ABSTRACTPMID:38096836 | DOI:10.1055/a-2218-6919 (Source: Hamostaseologie)
Source: Hamostaseologie - December 14, 2023 Category: Hematology Authors: Kaiqi Jia Manlin Zeng Xiaoyong Zheng Haixiao Xie Lihong Yang Yaosheng Xie Mingshan Wang Source Type: research
A German-Wide Systematic Study on Mobilization and Collection of Hematopoietic Stem Cells in Poor Mobilizer Patients with Multiple Myeloma prior to Autologous Stem Cell Transplantation
CONCLUSION: The OPTIMOB study showed that a considerable proportion of adult MM patients in Germany are PMs. Even though most of PMs were supported with PLX in the OPTIMOB study, PM-PLX also successfully mobilized HSCs, allowing ASCT in majority of all PMs. However, further analyses are required for treatment optimization in PMs.PMID:38089497 | PMC:PMC10712989 | DOI:10.1159/000531935 (Source: Hamostaseologie)
Source: Hamostaseologie - December 13, 2023 Category: Hematology Authors: Max Bittrich Katharina Kriegsmann Carola Tietze-Stolley Kamran Movassaghi Matthias Grube Vladan Vucinic Daniela Wehler Andreas Burchert Martin Schmidt-Hieber Andreas Rank Heinz A D ürk Bernd Metzner Christoph Kimmich Marcus Hentrich Christian Kunz Frank Source Type: research
A German-Wide Systematic Study on Mobilization and Collection of Hematopoietic Stem Cells in Poor Mobilizer Patients with Multiple Myeloma prior to Autologous Stem Cell Transplantation
CONCLUSION: The OPTIMOB study showed that a considerable proportion of adult MM patients in Germany are PMs. Even though most of PMs were supported with PLX in the OPTIMOB study, PM-PLX also successfully mobilized HSCs, allowing ASCT in majority of all PMs. However, further analyses are required for treatment optimization in PMs.PMID:38089497 | PMC:PMC10712989 | DOI:10.1159/000531935 (Source: Hamostaseologie)
Source: Hamostaseologie - December 13, 2023 Category: Hematology Authors: Max Bittrich Katharina Kriegsmann Carola Tietze-Stolley Kamran Movassaghi Matthias Grube Vladan Vucinic Daniela Wehler Andreas Burchert Martin Schmidt-Hieber Andreas Rank Heinz A D ürk Bernd Metzner Christoph Kimmich Marcus Hentrich Christian Kunz Frank Source Type: research
Classic Light Transmission Platelet Aggregometry: Do We Still Need it?
Hamostaseologie. 2023 Dec 8. doi: 10.1055/a-2117-4614. Online ahead of print.ABSTRACTFor more than 50 years, light transmission aggregometry has been accepted as the gold standard test for diagnosing inherited platelet disorders in platelet-rich plasma, although there are other functional approaches performed in whole blood. In this article, several advantages and disadvantages of this technique over other laboratory approaches are discussed in the view of recent guidelines, and the necessity of functional assays, such as light transmission aggregometry in the era of molecular genetic testing, is highlighted.PMID:38065556 ...
Source: Hamostaseologie - December 8, 2023 Category: Hematology Authors: Jennifer Gebetsberger Florian Pr üller Source Type: research
Classic Light Transmission Platelet Aggregometry: Do We Still Need it?
Hamostaseologie. 2023 Dec 8. doi: 10.1055/a-2117-4614. Online ahead of print.ABSTRACTFor more than 50 years, light transmission aggregometry has been accepted as the gold standard test for diagnosing inherited platelet disorders in platelet-rich plasma, although there are other functional approaches performed in whole blood. In this article, several advantages and disadvantages of this technique over other laboratory approaches are discussed in the view of recent guidelines, and the necessity of functional assays, such as light transmission aggregometry in the era of molecular genetic testing, is highlighted.PMID:38065556 ...
Source: Hamostaseologie - December 8, 2023 Category: Hematology Authors: Jennifer Gebetsberger Florian Pr üller Source Type: research
Classic Light Transmission Platelet Aggregometry: Do We Still Need it?
Hamostaseologie. 2023 Dec 8. doi: 10.1055/a-2117-4614. Online ahead of print.ABSTRACTFor more than 50 years, light transmission aggregometry has been accepted as the gold standard test for diagnosing inherited platelet disorders in platelet-rich plasma, although there are other functional approaches performed in whole blood. In this article, several advantages and disadvantages of this technique over other laboratory approaches are discussed in the view of recent guidelines, and the necessity of functional assays, such as light transmission aggregometry in the era of molecular genetic testing, is highlighted.PMID:38065556 ...
Source: Hamostaseologie - December 8, 2023 Category: Hematology Authors: Jennifer Gebetsberger Florian Pr üller Source Type: research
Classic Light Transmission Platelet Aggregometry: Do We Still Need it?
Hamostaseologie. 2023 Dec 8. doi: 10.1055/a-2117-4614. Online ahead of print.ABSTRACTFor more than 50 years, light transmission aggregometry has been accepted as the gold standard test for diagnosing inherited platelet disorders in platelet-rich plasma, although there are other functional approaches performed in whole blood. In this article, several advantages and disadvantages of this technique over other laboratory approaches are discussed in the view of recent guidelines, and the necessity of functional assays, such as light transmission aggregometry in the era of molecular genetic testing, is highlighted.PMID:38065556 ...
Source: Hamostaseologie - December 8, 2023 Category: Hematology Authors: Jennifer Gebetsberger Florian Pr üller Source Type: research
Emicizumab for the Treatment of Acquired Hemophilia A: Consensus Recommendations from the GTH-AHA Working Group
CONCLUSION: These GTH consensus recommendations provide guidance to physicians on the use of emicizumab in AHA and follow the results of clinical trials that have shown emicizumab is effective in preventing bleeding in AHA.PMID:38049124 | DOI:10.1055/a-2197-9738 (Source: Hamostaseologie)
Source: Hamostaseologie - December 4, 2023 Category: Hematology Authors: Christian Pfrepper Robert Klamroth Johannes Oldenburg Katharina Holstein Hermann Eichler Christina Hart Patrick Moehnle Kristina Schilling Karolin Trautmann-Grill Mohammed Alrifai Cihan Ay Wolfgang Miesbach Paul Knoebl Andreas Tiede Source Type: research
Emicizumab for the Treatment of Acquired Hemophilia A: Consensus Recommendations from the GTH-AHA Working Group
CONCLUSION: These GTH consensus recommendations provide guidance to physicians on the use of emicizumab in AHA and follow the results of clinical trials that have shown emicizumab is effective in preventing bleeding in AHA.PMID:38049124 | DOI:10.1055/a-2197-9738 (Source: Hamostaseologie)
Source: Hamostaseologie - December 4, 2023 Category: Hematology Authors: Christian Pfrepper Robert Klamroth Johannes Oldenburg Katharina Holstein Hermann Eichler Christina Hart Patrick Moehnle Kristina Schilling Karolin Trautmann-Grill Mohammed Alrifai Cihan Ay Wolfgang Miesbach Paul Knoebl Andreas Tiede Source Type: research
Emicizumab for the Treatment of Acquired Hemophilia A: Consensus Recommendations from the GTH-AHA Working Group
CONCLUSION: These GTH consensus recommendations provide guidance to physicians on the use of emicizumab in AHA and follow the results of clinical trials that have shown emicizumab is effective in preventing bleeding in AHA.PMID:38049124 | DOI:10.1055/a-2197-9738 (Source: Hamostaseologie)
Source: Hamostaseologie - December 4, 2023 Category: Hematology Authors: Christian Pfrepper Robert Klamroth Johannes Oldenburg Katharina Holstein Hermann Eichler Christina Hart Patrick Moehnle Kristina Schilling Karolin Trautmann-Grill Mohammed Alrifai Cihan Ay Wolfgang Miesbach Paul Knoebl Andreas Tiede Source Type: research
