Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research

Exosome complex components 1 and 2 are vital for early mammalian development
Gene Expr Patterns. 2023 Nov 7;51:119346. doi: 10.1016/j.gep.2023.119346. Online ahead of print.ABSTRACTExosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5' → 3' RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization of early lethal alleles produced by the Knockout Mouse Project, we have examined Exosc1 and Exosc2 homozygous null (mutant)...
Source: Gene Expression Patterns : GEP - November 8, 2023 Category: Genetics & Stem Cells Authors: Sanjana Srinivasan Xinjian He Sarah Mirza Jesse Mager Source Type: research