Identification of novel candidate genes leading to sex differentiation in primordial germ cells of Drosophila
Gene Expr Patterns. 2023 May 2:119321. doi: 10.1016/j.gep.2023.119321. Online ahead of print.ABSTRACTGermline sex determination and differentiation are pivotal processes in reproduction. In Drosophila, sex determination of the germline occurs in primordial germ cells (PGCs), and the sex differentiation of these cells is initiated during embryogenesis. However, the molecular mechanism initiating sex differentiation remains elusive. To address this issue, we identified sex-biased genes using RNA-sequencing data of male and female PGCs. Our research revealed 497 genes that were differentially expressed more than twofold betwe...
Source: Gene Expression Patterns : GEP - May 4, 2023 Category: Genetics & Stem Cells Authors: Ryoma Ota Hiroki Miura Masaki Masukawa Makoto Hayashi Satoru Kobayashi Source Type: research
Expression analysis of the Tao kinase family of Ste20p-like map kinase kinase kinases during early embryonic development in Xenopus laevis
Gene Expr Patterns. 2023 Apr 1:119318. doi: 10.1016/j.gep.2023.119318. Online ahead of print.ABSTRACTDevelopment of the vertebrate embryo requires strict coordination of a highly complex series of signaling cascades, that drive cell proliferation, differentiation, migration, and the general morphogenetic program. Members of the Map kinase signaling pathway are repeatedly required throughout development to activate the downstream effectors, ERK, p38, and JNK. Regulation of these pathways occurs at many levels in the signaling cascade, with the Map3Ks playing an essential role in target selection. The thousand and one amino ...
Source: Gene Expression Patterns : GEP - April 3, 2023 Category: Genetics & Stem Cells Authors: Michael D Yoder Steven Van Osten Gregory F Weber Source Type: research
Expression analysis of the Tao kinase family of Ste20p-like map kinase kinase kinases during early embryonic development in Xenopus laevis
Gene Expr Patterns. 2023 Apr 1:119318. doi: 10.1016/j.gep.2023.119318. Online ahead of print.ABSTRACTDevelopment of the vertebrate embryo requires strict coordination of a highly complex series of signaling cascades, that drive cell proliferation, differentiation, migration, and the general morphogenetic program. Members of the Map kinase signaling pathway are repeatedly required throughout development to activate the downstream effectors, ERK, p38, and JNK. Regulation of these pathways occurs at many levels in the signaling cascade, with the Map3Ks playing an essential role in target selection. The thousand and one amino ...
Source: Gene Expression Patterns : GEP - April 3, 2023 Category: Genetics & Stem Cells Authors: Michael D Yoder Steven Van Osten Gregory F Weber Source Type: research
Expression analysis of the Tao kinase family of Ste20p-like map kinase kinase kinases during early embryonic development in Xenopus laevis
Gene Expr Patterns. 2023 Apr 1:119318. doi: 10.1016/j.gep.2023.119318. Online ahead of print.ABSTRACTDevelopment of the vertebrate embryo requires strict coordination of a highly complex series of signaling cascades, that drive cell proliferation, differentiation, migration, and the general morphogenetic program. Members of the Map kinase signaling pathway are repeatedly required throughout development to activate the downstream effectors, ERK, p38, and JNK. Regulation of these pathways occurs at many levels in the signaling cascade, with the Map3Ks playing an essential role in target selection. The thousand and one amino ...
Source: Gene Expression Patterns : GEP - April 3, 2023 Category: Genetics & Stem Cells Authors: Michael D Yoder Steven Van Osten Gregory F Weber Source Type: research
Expression analysis of the Tao kinase family of Ste20p-like map kinase kinase kinases during early embryonic development in Xenopus laevis
Gene Expr Patterns. 2023 Apr 1:119318. doi: 10.1016/j.gep.2023.119318. Online ahead of print.ABSTRACTDevelopment of the vertebrate embryo requires strict coordination of a highly complex series of signaling cascades, that drive cell proliferation, differentiation, migration, and the general morphogenetic program. Members of the Map kinase signaling pathway are repeatedly required throughout development to activate the downstream effectors, ERK, p38, and JNK. Regulation of these pathways occurs at many levels in the signaling cascade, with the Map3Ks playing an essential role in target selection. The thousand and one amino ...
Source: Gene Expression Patterns : GEP - April 3, 2023 Category: Genetics & Stem Cells Authors: Michael D Yoder Steven Van Osten Gregory F Weber Source Type: research
