Transcriptional regulation of the alternative sex hormone-binding globulin promoter by KLF4
Gene Expr Patterns. 2024 Mar 7:119357. doi: 10.1016/j.gep.2024.119357. Online ahead of print.ABSTRACTIn most mammals the major site of sex hormone-binding globulin (SHBG) synthesis is the liver wherefrom it is secreted into the bloodstream and is the primary determinant of sex steroid access to target tissues. The minor site of SHBG synthesis is the testis and in lower mammals testicular SHBG has long been known to be synthesized and secreted by Sertoli cells. However, human testicular SHBG is expressed in developing germ cells from an upstream alternative promoter (altP-SHBG). Transcripts arising from this region comprise...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Warren M Meyers Source Type: research
Ontogeny and tissue specific expression profiles of recombination activating genes (RAGs) during development in Nile tilapia, Oreochromisniloticus
Gene Expr Patterns. 2024 Mar 7;52:119358. doi: 10.1016/j.gep.2024.119358. Online ahead of print.ABSTRACTRecombination activating genes (RAGs) mediates the process of rearrangement and somatic recombination (V(D)J) to generate different antibody repertoire. Studies on the expression pattern of adaptive immune genes during ontogenic development are crucial for the formulation of fish immunization strategy. In the present study, Nile tilapia was taken to explore the relative expression profile of RAG genes during their developmental stages. The developmental stages of Nile tilapia, i.e., unfertilized egg, 0, 2, 4, 6, 8, 10, 1...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Ravikumar M Chovatia Arpit Acharya Kiran D Rasal Megha Kadam Bedekar Kezhedath Jeena R Bharathi Rathinam Chandana Dinakaran Gayatri Tripathi Source Type: research
Transcriptional regulation of the alternative sex hormone-binding globulin promoter by KLF4
Gene Expr Patterns. 2024 Mar 7:119357. doi: 10.1016/j.gep.2024.119357. Online ahead of print.ABSTRACTIn most mammals the major site of sex hormone-binding globulin (SHBG) synthesis is the liver wherefrom it is secreted into the bloodstream and is the primary determinant of sex steroid access to target tissues. The minor site of SHBG synthesis is the testis and in lower mammals testicular SHBG has long been known to be synthesized and secreted by Sertoli cells. However, human testicular SHBG is expressed in developing germ cells from an upstream alternative promoter (altP-SHBG). Transcripts arising from this region comprise...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Warren M Meyers Source Type: research
Ontogeny and tissue specific expression profiles of recombination activating genes (RAGs) during development in Nile tilapia, Oreochromisniloticus
Gene Expr Patterns. 2024 Mar 7;52:119358. doi: 10.1016/j.gep.2024.119358. Online ahead of print.ABSTRACTRecombination activating genes (RAGs) mediates the process of rearrangement and somatic recombination (V(D)J) to generate different antibody repertoire. Studies on the expression pattern of adaptive immune genes during ontogenic development are crucial for the formulation of fish immunization strategy. In the present study, Nile tilapia was taken to explore the relative expression profile of RAG genes during their developmental stages. The developmental stages of Nile tilapia, i.e., unfertilized egg, 0, 2, 4, 6, 8, 10, 1...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Ravikumar M Chovatia Arpit Acharya Kiran D Rasal Megha Kadam Bedekar Kezhedath Jeena R Bharathi Rathinam Chandana Dinakaran Gayatri Tripathi Source Type: research
Gene expression analysis of oxidative stress-related genes in the apical, middle, and basal turns of the cochlea
This study summarized the data for the gradient of expression of oxidative stress-related genes in the cochlea and found potential candidate targets for prevention of ototoxic deafness, which may provide new insights for cochlear pathology.PMID:38432189 | DOI:10.1016/j.gep.2024.119356 (Source: Gene Expression Patterns : GEP)
Source: Gene Expression Patterns : GEP - March 3, 2024 Category: Genetics & Stem Cells Authors: Yang Yang Xin Chen Chaoyong Tian Bei Fan Xiaogang An Zhenzhen Liu Qiong Li Wenjuan Mi Ying Lin Dingjun Zha Source Type: research
Gene expression analysis of oxidative stress-related genes in the apical, middle, and basal turns of the cochlea
This study summarized the data for the gradient of expression of oxidative stress-related genes in the cochlea and found potential candidate targets for prevention of ototoxic deafness, which may provide new insights for cochlear pathology.PMID:38432189 | DOI:10.1016/j.gep.2024.119356 (Source: Gene Expression Patterns : GEP)
Source: Gene Expression Patterns : GEP - March 3, 2024 Category: Genetics & Stem Cells Authors: Yang Yang Xin Chen Chaoyong Tian Bei Fan Xiaogang An Zhenzhen Liu Qiong Li Wenjuan Mi Ying Lin Dingjun Zha Source Type: research
Gene expression analysis of oxidative stress-related genes in the apical, middle, and basal turns of the cochlea
This study summarized the data for the gradient of expression of oxidative stress-related genes in the cochlea and found potential candidate targets for prevention of ototoxic deafness, which may provide new insights for cochlear pathology.PMID:38432189 | DOI:10.1016/j.gep.2024.119356 (Source: Gene Expression Patterns : GEP)
Source: Gene Expression Patterns : GEP - March 3, 2024 Category: Genetics & Stem Cells Authors: Yang Yang Xin Chen Chaoyong Tian Bei Fan Xiaogang An Zhenzhen Liu Qiong Li Wenjuan Mi Ying Lin Dingjun Zha Source Type: research
Gene expression analysis of oxidative stress-related genes in the apical, middle, and basal turns of the cochlea
This study summarized the data for the gradient of expression of oxidative stress-related genes in the cochlea and found potential candidate targets for prevention of ototoxic deafness, which may provide new insights for cochlear pathology.PMID:38432189 | DOI:10.1016/j.gep.2024.119356 (Source: Gene Expression Patterns : GEP)
Source: Gene Expression Patterns : GEP - March 3, 2024 Category: Genetics & Stem Cells Authors: Yang Yang Xin Chen Chaoyong Tian Bei Fan Xiaogang An Zhenzhen Liu Qiong Li Wenjuan Mi Ying Lin Dingjun Zha Source Type: research
Gene expression analysis of oxidative stress-related genes in the apical, middle, and basal turns of the cochlea
This study summarized the data for the gradient of expression of oxidative stress-related genes in the cochlea and found potential candidate targets for prevention of ototoxic deafness, which may provide new insights for cochlear pathology.PMID:38432189 | DOI:10.1016/j.gep.2024.119356 (Source: Gene Expression Patterns : GEP)
Source: Gene Expression Patterns : GEP - March 3, 2024 Category: Genetics & Stem Cells Authors: Yang Yang Xin Chen Chaoyong Tian Bei Fan Xiaogang An Zhenzhen Liu Qiong Li Wenjuan Mi Ying Lin Dingjun Zha Source Type: research
Gene expression analysis of oxidative stress-related genes in the apical, middle, and basal turns of the cochlea
This study summarized the data for the gradient of expression of oxidative stress-related genes in the cochlea and found potential candidate targets for prevention of ototoxic deafness, which may provide new insights for cochlear pathology.PMID:38432189 | DOI:10.1016/j.gep.2024.119356 (Source: Gene Expression Patterns : GEP)
Source: Gene Expression Patterns : GEP - March 3, 2024 Category: Genetics & Stem Cells Authors: Yang Yang Xin Chen Chaoyong Tian Bei Fan Xiaogang An Zhenzhen Liu Qiong Li Wenjuan Mi Ying Lin Dingjun Zha Source Type: research
Embryonic expression patterns of TBL1 family in zebrafish
Gene Expr Patterns. 2024 Jan 23;51:119355. doi: 10.1016/j.gep.2024.119355. Online ahead of print.ABSTRACTExcept the addition of TBL1Y in human, transducing beta like 1 (TBL1) family mainly consists of two members TBL1X and TBL1XR1, taking part in multiple intracellular signaling pathways such as Wnt/β-catenin and NF-κB in cancer progression. However, the gene expression patterns of this family during embryonic development remain largely unknown. Here we took advantage of zebrafish model to characterize the spatial and temporal expression patterns of TBL1 family genes including tbl1x, tbl1xr1a and tbl1xr1b. The in situ hy...
Source: Gene Expression Patterns : GEP - January 25, 2024 Category: Genetics & Stem Cells Authors: Yuanqi Jia Qiu Jiang Shuna Sun Source Type: research
Embryonic expression patterns of TBL1 family in zebrafish
Gene Expr Patterns. 2024 Jan 23;51:119355. doi: 10.1016/j.gep.2024.119355. Online ahead of print.ABSTRACTExcept the addition of TBL1Y in human, transducing beta like 1 (TBL1) family mainly consists of two members TBL1X and TBL1XR1, taking part in multiple intracellular signaling pathways such as Wnt/β-catenin and NF-κB in cancer progression. However, the gene expression patterns of this family during embryonic development remain largely unknown. Here we took advantage of zebrafish model to characterize the spatial and temporal expression patterns of TBL1 family genes including tbl1x, tbl1xr1a and tbl1xr1b. The in situ hy...
Source: Gene Expression Patterns : GEP - January 25, 2024 Category: Genetics & Stem Cells Authors: Yuanqi Jia Qiu Jiang Shuna Sun Source Type: research
Embryonic expression patterns of TBL1 family in zebrafish
Gene Expr Patterns. 2024 Jan 23;51:119355. doi: 10.1016/j.gep.2024.119355. Online ahead of print.ABSTRACTExcept the addition of TBL1Y in human, transducing beta like 1 (TBL1) family mainly consists of two members TBL1X and TBL1XR1, taking part in multiple intracellular signaling pathways such as Wnt/β-catenin and NF-κB in cancer progression. However, the gene expression patterns of this family during embryonic development remain largely unknown. Here we took advantage of zebrafish model to characterize the spatial and temporal expression patterns of TBL1 family genes including tbl1x, tbl1xr1a and tbl1xr1b. The in situ hy...
Source: Gene Expression Patterns : GEP - January 25, 2024 Category: Genetics & Stem Cells Authors: Yuanqi Jia Qiu Jiang Shuna Sun Source Type: research
Embryonic expression patterns of TBL1 family in zebrafish
Gene Expr Patterns. 2024 Jan 23;51:119355. doi: 10.1016/j.gep.2024.119355. Online ahead of print.ABSTRACTExcept the addition of TBL1Y in human, transducing beta like 1 (TBL1) family mainly consists of two members TBL1X and TBL1XR1, taking part in multiple intracellular signaling pathways such as Wnt/β-catenin and NF-κB in cancer progression. However, the gene expression patterns of this family during embryonic development remain largely unknown. Here we took advantage of zebrafish model to characterize the spatial and temporal expression patterns of TBL1 family genes including tbl1x, tbl1xr1a and tbl1xr1b. The in situ hy...
Source: Gene Expression Patterns : GEP - January 25, 2024 Category: Genetics & Stem Cells Authors: Yuanqi Jia Qiu Jiang Shuna Sun Source Type: research
Embryonic expression patterns of TBL1 family in zebrafish
Gene Expr Patterns. 2024 Jan 23;51:119355. doi: 10.1016/j.gep.2024.119355. Online ahead of print.ABSTRACTExcept the addition of TBL1Y in human, transducing beta like 1 (TBL1) family mainly consists of two members TBL1X and TBL1XR1, taking part in multiple intracellular signaling pathways such as Wnt/β-catenin and NF-κB in cancer progression. However, the gene expression patterns of this family during embryonic development remain largely unknown. Here we took advantage of zebrafish model to characterize the spatial and temporal expression patterns of TBL1 family genes including tbl1x, tbl1xr1a and tbl1xr1b. The in situ hy...
Source: Gene Expression Patterns : GEP - January 25, 2024 Category: Genetics & Stem Cells Authors: Yuanqi Jia Qiu Jiang Shuna Sun Source Type: research
