Phosphatidylinositol 3 kinase inhibitor-related pneumonitis: a systematic review and meta-analysis
CONCLUSION: PI3K inhibitors significantly increased the risk of pneumonitis compared with controls, and most cases are severe or even life-threatening.PROSPERO REGISTRATION NUMBER: CRD42022318878.PMID:37489925 | DOI:10.1080/17512433.2023.2238602 (Source: Expert Review of Clinical Pharmacology)
Source: Expert Review of Clinical Pharmacology - July 25, 2023 Category: Drugs & Pharmacology Authors: Yi Zhang Zhuo Ma Yushu Wang Xin Feng Zhuoling An Source Type: research

Is ranitidine necessary as premedication for regimens containing paclitaxel? A non-inferiority study
CONCLUSIONS: This study demonstrates that the elimination of ranitidine from paclitaxel premedication schedules is non-inferior in the development of HRs of any grade compared to the administration of H2-antagonists.PMID:37477611 | DOI:10.1080/17512433.2023.2238596 (Source: Expert Review of Clinical Pharmacology)
Source: Expert Review of Clinical Pharmacology - July 21, 2023 Category: Drugs & Pharmacology Authors: Olalla Montero P érez Javier Martinez Benavides Tania Gonz ález Fernandez Silvia Guerra Prio Roc ío Romero Domínguez Ricard Mes ía Nin Ana Clop és Estela Source Type: research