Expert Review of Clinical Pharmacology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Treatment resistance in pancreatic and biliary tract cancer: molecular and clinical pharmacology perspectives
Expert Rev Clin Pharmacol. 2024 Feb 27. doi: 10.1080/17512433.2024.2319340. Online ahead of print.ABSTRACTINTRODUCTION: Treatment resistance poses a significant obstacle in oncology, especially in biliary tract cancer (BTC) and pancreatic cancer (PC). Current therapeutic options include chemotherapy, targeted therapy, and immunotherapy. Resistance to these treatments may arise due to diverse molecular mechanisms, such as genetic and epigenetic modifications, altered drug metabolism and efflux, and changes in the tumor microenvironment. Identifying and overcoming these mechanisms is a major focus of research: strategies bei...
Source: Expert Review of Clinical Pharmacology - February 27, 2024 Category: Drugs & Pharmacology Authors: Bel én Toledo Chiara Deiana Fabio Scian ò Giovanni Brandi Juan Antonio Marchal Macarena Per án Elisa Giovannetti Source Type: research

Antiretroviral therapy response: exploring the potential influence of SARS-CoV-2
Expert Rev Clin Pharmacol. 2024 Feb 28:1-4. doi: 10.1080/17512433.2024.2322984. Online ahead of print.NO ABSTRACTPMID:38390721 | DOI:10.1080/17512433.2024.2322984 (Source: Expert Review of Clinical Pharmacology)
Source: Expert Review of Clinical Pharmacology - February 23, 2024 Category: Drugs & Pharmacology Authors: Ahmad Z Al Meslamani Source Type: research

Antiretroviral therapy response: exploring the potential influence of SARS-CoV-2
Expert Rev Clin Pharmacol. 2024 Feb 23. doi: 10.1080/17512433.2024.2322984. Online ahead of print.NO ABSTRACTPMID:38390721 | DOI:10.1080/17512433.2024.2322984 (Source: Expert Review of Clinical Pharmacology)
Source: Expert Review of Clinical Pharmacology - February 23, 2024 Category: Drugs & Pharmacology Authors: Ahmad Z Al Meslamani Source Type: research

Therapeutic drug monitoring of antifungal therapies: do we really need it and what are the best practices?
Expert Rev Clin Pharmacol. 2024 Feb 21:1-13. doi: 10.1080/17512433.2024.2317293. Online ahead of print.ABSTRACTINTRODUCTION: Despite advancements, invasive fungal infections (IFI) still carry high mortality rates, often exceeding 30%. The challenges in diagnosis, coupled with limited effective antifungal options, make managing IFIs complex. Antifungal drugs are essential for IFI management, but their efficacy can be diminished by drug-drug interactions and pharmacokinetic variability. Therapeutic Drug Monitoring (TDM), especially in the context of triazole use, has emerged as a valuable strategy to optimize antifungal ther...
Source: Expert Review of Clinical Pharmacology - February 21, 2024 Category: Drugs & Pharmacology Authors: Johannes Boyer Martin Hoenigl Lisa Kriegl Source Type: research

Centering the patient in decisions about opioid tapering
Expert Rev Clin Pharmacol. 2024 Feb 13:1-3. doi: 10.1080/17512433.2024.2318470. Online ahead of print.NO ABSTRACTPMID:38349034 | DOI:10.1080/17512433.2024.2318470 (Source: Expert Review of Clinical Pharmacology)
Source: Expert Review of Clinical Pharmacology - February 13, 2024 Category: Drugs & Pharmacology Authors: J J Fenton Source Type: research

The effect of epilepsy and antiseizure medications on cardiac autonomic functions in children with epilepsy
CONCLUSIONS: Parasympathetic and sympathetic autonomic hypofunctions are common in children with epilepsy. This could be due to the depressant effect of sodium channel blocker ASMs on central and/or cardiac autonomic systems.PMID:38349326 | DOI:10.1080/17512433.2024.2318469 (Source: Expert Review of Clinical Pharmacology)
Source: Expert Review of Clinical Pharmacology - February 13, 2024 Category: Drugs & Pharmacology Authors: Sherifa Ahmed Hamed Ali Farrag El Hadad Mohammed Aboalwafa Aladawy Source Type: research