Disrupted gut microecology after high-dose 131I therapy and radioprotective effects of arachidonic acid supplementation
ConclusionThese findings highlight that ARA, as a key metabolite, substantially contributes to radioprotection. Our study provides novel insights into the pivotal role that the microbiota-metabolite axis plays in radionuclide protection and offers effective biological targets for treating radiation-induced adverse effects. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

The effect of prednisolone and a short-term prednisolone discontinuation for the diagnostic accuracy of FDG-PET/CT in polymyalgia rheumatica —a prospective study of 101 patients
ConclusionFDG-PET/CT has limited diagnostic accuracy for differentiating PMR from other inflammatory diseases. If FDG-PET/CT is intended for diagnostic purposes, prednisolone should be discontinued to enhance diagnostic accuracy.Trial registrationClinicalTrials.gov (NCT04519580). Registered 17th of August 2020. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

The status of nuclear medicine in China: the first official national survey
ConclusionThese results of the first official survey towards current status of nuclear medicine in China are the foundation for the establishment of the quality control management system. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Clinical translation of a novel FAPI dimer [68Ga]Ga-LNC1013
ConclusionDimerization is an effective strategy to produce FAPI derivatives with favorable tumor uptake, long tumor retention, and imaging contrast over its monomeric counterpart. We demonstrated that [68Ga]Ga-LNC1013, the lead compound without any piperazine moiety, had superior diagnostic potential over [68Ga]Ga-FAPI-46 and18F-FDG, suggesting the future potential of LNC1013 for radioligand therapy of FAP-positive cancers. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Initial [18F]DCFPyL PET/CT in treatment-na ïve prostate cancer: correlation with post-ADT PSA outcomes and recurrence
ConclusionOur study revealed that pretreatment [18F]DCFPyL uptake in primary or metastatic tumor sites is prognostically relevant in high-risk PCa patients undergoing ADT.Further research is needed to develop robust predictive models in this multifaceted landscape of PCa management. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Targeted interleukin-2 enhances the in vivo anti-cancer activity of Pluvicto ™
ConclusionThe therapeutic efficacy of Pluvicto ™ at low radioactive doses can be effectively enhanced by the combination with L19-IL2. Our findings warrant further clinical exploration of this novel combination modality. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Disrupted gut microecology after high-dose 131I therapy and radioprotective effects of arachidonic acid supplementation
ConclusionThese findings highlight that ARA, as a key metabolite, substantially contributes to radioprotection. Our study provides novel insights into the pivotal role that the microbiota-metabolite axis plays in radionuclide protection and offers effective biological targets for treating radiation-induced adverse effects. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Letter to the Editor: FDG Liver Biodistribution
(Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - March 30, 2024 Category: Nuclear Medicine Source Type: research

The EANM Focus 5 consensus on ‘molecular imaging and theranostics in prostate cancer’: the future begins today
(Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - March 30, 2024 Category: Nuclear Medicine Source Type: research

Advances in targeted alpha therapy of cancer
(Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - March 30, 2024 Category: Nuclear Medicine Source Type: research

After one year of ChatGPT ’s launch: reflections on artificial intelligence in scientific writing
(Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - March 30, 2024 Category: Nuclear Medicine Source Type: research

Letter to the Editor: FDG Liver Biodistribution
(Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - March 21, 2024 Category: Nuclear Medicine Source Type: research

The EANM Focus 5 consensus on ‘molecular imaging and theranostics in prostate cancer’: the future begins today
(Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - March 21, 2024 Category: Nuclear Medicine Source Type: research

After one year of ChatGPT ’s launch: reflections on artificial intelligence in scientific writing
(Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - March 21, 2024 Category: Nuclear Medicine Source Type: research

“Metabolic fingerprints” of cachexia in lung cancer patients
(Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - March 20, 2024 Category: Nuclear Medicine Source Type: research