European Journal of Nuclear Medicine and Molecular Imaging This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Highlights of the 36th EANM Annual Congress 2023, from hometown Vienna, Austria: “A SYMPHONY OF SCIENCE”
(Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 4, 2024 Category: Nuclear Medicine Source Type: research

Optimizing the pharmacokinetics of an 211At-labeled RGD peptide with an albumin-binding moiety via the administration of an albumin-binding inhibitor
ConclusionIPBA administration (as an albumin-binding inhibitor) could modulate the pharmacokinetics and enhance the therapeutic effects of [211At]1. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 4, 2024 Category: Nuclear Medicine Source Type: research

Latent phosphaturic mesenchymal tumor in left planta detected by [18F]F-AlF-NOTA-octreotide PET/CT
(Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 3, 2024 Category: Nuclear Medicine Source Type: research

The effect of prednisolone and a short-term prednisolone discontinuation for the diagnostic accuracy of FDG-PET/CT in polymyalgia rheumatica —a prospective study of 101 patients
ConclusionFDG-PET/CT has limited diagnostic accuracy for differentiating PMR from other inflammatory diseases. If FDG-PET/CT is intended for diagnostic purposes, prednisolone should be discontinued to enhance diagnostic accuracy.Trial registrationClinicalTrials.gov (NCT04519580). Registered 17th of August 2020. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

The status of nuclear medicine in China: the first official national survey
ConclusionThese results of the first official survey towards current status of nuclear medicine in China are the foundation for the establishment of the quality control management system. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Clinical translation of a novel FAPI dimer [68Ga]Ga-LNC1013
ConclusionDimerization is an effective strategy to produce FAPI derivatives with favorable tumor uptake, long tumor retention, and imaging contrast over its monomeric counterpart. We demonstrated that [68Ga]Ga-LNC1013, the lead compound without any piperazine moiety, had superior diagnostic potential over [68Ga]Ga-FAPI-46 and18F-FDG, suggesting the future potential of LNC1013 for radioligand therapy of FAP-positive cancers. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Initial [18F]DCFPyL PET/CT in treatment-na ïve prostate cancer: correlation with post-ADT PSA outcomes and recurrence
ConclusionOur study revealed that pretreatment [18F]DCFPyL uptake in primary or metastatic tumor sites is prognostically relevant in high-risk PCa patients undergoing ADT.Further research is needed to develop robust predictive models in this multifaceted landscape of PCa management. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Targeted interleukin-2 enhances the in vivo anti-cancer activity of Pluvicto ™
ConclusionThe therapeutic efficacy of Pluvicto ™ at low radioactive doses can be effectively enhanced by the combination with L19-IL2. Our findings warrant further clinical exploration of this novel combination modality. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Disrupted gut microecology after high-dose 131I therapy and radioprotective effects of arachidonic acid supplementation
ConclusionThese findings highlight that ARA, as a key metabolite, substantially contributes to radioprotection. Our study provides novel insights into the pivotal role that the microbiota-metabolite axis plays in radionuclide protection and offers effective biological targets for treating radiation-induced adverse effects. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

The effect of prednisolone and a short-term prednisolone discontinuation for the diagnostic accuracy of FDG-PET/CT in polymyalgia rheumatica —a prospective study of 101 patients
ConclusionFDG-PET/CT has limited diagnostic accuracy for differentiating PMR from other inflammatory diseases. If FDG-PET/CT is intended for diagnostic purposes, prednisolone should be discontinued to enhance diagnostic accuracy.Trial registrationClinicalTrials.gov (NCT04519580). Registered 17th of August 2020. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

The status of nuclear medicine in China: the first official national survey
ConclusionThese results of the first official survey towards current status of nuclear medicine in China are the foundation for the establishment of the quality control management system. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Clinical translation of a novel FAPI dimer [68Ga]Ga-LNC1013
ConclusionDimerization is an effective strategy to produce FAPI derivatives with favorable tumor uptake, long tumor retention, and imaging contrast over its monomeric counterpart. We demonstrated that [68Ga]Ga-LNC1013, the lead compound without any piperazine moiety, had superior diagnostic potential over [68Ga]Ga-FAPI-46 and18F-FDG, suggesting the future potential of LNC1013 for radioligand therapy of FAP-positive cancers. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Initial [18F]DCFPyL PET/CT in treatment-na ïve prostate cancer: correlation with post-ADT PSA outcomes and recurrence
ConclusionOur study revealed that pretreatment [18F]DCFPyL uptake in primary or metastatic tumor sites is prognostically relevant in high-risk PCa patients undergoing ADT.Further research is needed to develop robust predictive models in this multifaceted landscape of PCa management. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Targeted interleukin-2 enhances the in vivo anti-cancer activity of Pluvicto ™
ConclusionThe therapeutic efficacy of Pluvicto ™ at low radioactive doses can be effectively enhanced by the combination with L19-IL2. Our findings warrant further clinical exploration of this novel combination modality. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research