Exceptionally high levels of total mercury in deep-sea sharks of the Southeastern Mediterranean sea over the last ∼ 40 years
Environ Int. 2024 Apr 15;187:108661. doi: 10.1016/j.envint.2024.108661. Online ahead of print.ABSTRACTDeep-sea habitats are currently recognized as a hot spot for mercury (Hg) accumulation from anthropogenic sources, resulting in elevated concentrations of total mercury (THg) in deep-sea megafauna. Among them, deep-sea sharks (Class Chondrichthyes) are characterized by high trophic position and extended longevity and are, therefore, at high risk for mercury contamination. Despite this, sharks are overexploited by fishing activity in increasingly deeper water, worldwide, imposing health risks to human consumption. While it ...
Source: Environment International - April 30, 2024 Category: Environmental Health Authors: Guy Sisma-Ventura Jacob Silverman Yael Segal Hagar Hauzer Maria Abu Khadra Nir Stern Tamar Guy-Haim Barak Herut Source Type: research
Urban indoor gardening enhances immune regulation and diversifies skin microbiota - A placebo-controlled double-blinded intervention study
Environ Int. 2024 Apr 26;187:108705. doi: 10.1016/j.envint.2024.108705. Online ahead of print.ABSTRACTAccording to the hygiene and biodiversity hypotheses, frequent exposure to environmental microbiota, especially through soil contact, diversifies commensal microbiota, enhances immune modulation, and ultimately lowers the risk of immune-mediated diseases. Here we test the underlying assumption of the hygiene and biodiversity hypotheses by instructing volunteers to grow edible plants indoors during the winter season when natural exposure to environmental microbiota is low. The one-month randomized, placebo-controlled double...
Source: Environment International - April 30, 2024 Category: Environmental Health Authors: Mika Saarenp ää Marja I Roslund Noora Nurminen Riikka Puhakka Laura Kummola Olli H Laitinen Heikki Hy öty Aki Sinkkonen Source Type: research
Thermal stress and hospital admissions for cardiorespiratory disease in Brazil
In this study, we explored the association between thermal indices and hospital admissions for circulatory and respiratory diseases in Brazil. We used an extensive dataset spanning 11 years (2008-2018) from the Brazilian Ministry of Health, encompassing a total of 23,791,093 hospitalizations for circulatory and respiratory diseases. We considered four distinct thermal indices-Discomfort Index (DI), Net Effective Temperature (NET), Humidex (H), and Heat Index (HI). We used an extension of the two-stage design with a case time series to assess this relationship. In the first stage, we applied a distributed lag non-linear mod...
Source: Environment International - April 30, 2024 Category: Environmental Health Authors: Weeberb J Requia Francisco Jablinski Castelhano Julia Moore Reizane Maria Damasceno da Silva Mariana Andreotti Dias Source Type: research
Paternal exposures to endocrine-disrupting chemicals induce intergenerational epigenetic influences on offspring: A review
Environ Int. 2024 Apr 24;187:108689. doi: 10.1016/j.envint.2024.108689. Online ahead of print.ABSTRACTEndocrine-disrupting chemicals (EDCs) are ubiquitous in ecological environments and have become a great issue of public health concern since the 1990 s. There is a deep scientific understanding of the toxicity of EDCs. However, recent studies have found that the abnormal physiological functions of the parents caused by EDCs could be transmitted to their unexposed offspring, leading to intergenerational toxicity. We questioned whether sustained epigenetic changes occur through the male germline. In this review, we (1) syste...
Source: Environment International - April 30, 2024 Category: Environmental Health Authors: Yinan Zhang Bingyi Wang Wenhui Sun Guanghui Wang Zhiquan Liu Xiaofang Zhang Jiafeng Ding Yu Han Hangjun Zhang Source Type: research
Mechanism of circRNA_SMG6 mediating lung macrophage ECM degradation via miR-570-3p in microplastics-induced emphysema
Environ Int. 2024 Apr 25;187:108701. doi: 10.1016/j.envint.2024.108701. Online ahead of print.ABSTRACTMicroplastics (MPs) are plastic particles < 5 mm in diameter, of which polystyrene microplastics (PS-MPs) are representative type. The extracellular matrix (ECM) degradation of macrophages is associated with the development of emphysema. Additionally, circular RNAs (circRNAs) have a regulatory role in epigenetic mechanisms related to lung disease. However, the mechanisms of the ECM degradation and circRNAs in MPs-induced emphysema are still unclear. In our study, Sprague-Dawley (SD) rats were treated with 0, 0.5, 1.0 an...
Source: Environment International - April 30, 2024 Category: Environmental Health Authors: Xiaoxue Sun Tian Xiao Junjie Qin Yan Song Kuikui Lu Ruoheng Ding Weiqing Shi Qian Bian Source Type: research
Multi-omics approach characterizes the role of Bisphenol F in disrupting hepatic lipid metabolism
Environ Int. 2024 Apr 24;187:108690. doi: 10.1016/j.envint.2024.108690. Online ahead of print.ABSTRACTBisphenol F (BPF), a substitute for bisphenol A (BPA), is ubiquitous existed in various environmental media. Exposure to BPF may promote non-alcoholic fatty liver disease (NAFLD), while the potential mechanism is still unknown. In current study, we used in vitro and in vivo model to evaluate its hepatotoxicity and molecular mechanism. Using multi-omics approach, we found that BPF exposure led to changes in hepatic transcriptome, metabolome and chromatin accessible regions that were enriched for binding sites of transcripti...
Source: Environment International - April 30, 2024 Category: Environmental Health Authors: Yun Fan Shiqi Li Xiancheng Yang Shengjun Bai Min Tang Xueer Zhang Chuncheng Lu Chenbo Ji Guizhen Du Yufeng Qin Source Type: research
Assembly and succession of the phyllosphere microbiome and nutrient-cycling genes during plant community development in a glacier foreland
In this study, considering core and satellite microbial taxa, we characterized the phyllosphere microbiome and functional genes in various microhabitats (i.e., leaf litter, moss and plant leaves) across the succession of a plant community in a low-altitude glacier foreland. Our findings indicate that phyllosphere microbiomes and associated ecosystem stability increase during the succession of the plant community. The abundance of core taxa increased with plant community succession and was primarily governed by deterministic processes. In contrast, satellite taxa abundance decreased during plant community succession and was...
Source: Environment International - April 30, 2024 Category: Environmental Health Authors: Jian Li Ming-Kang Jin Lijie Huang Zhan-Feng Liu Tao Wang Rui-Ying Chang Michiel Op de Beeck Hans Lambers Dafeng Hui Ke-Qing Xiao Qing-Lin Chen Jordi Sardans Josep Pe ñuelas Xiao-Ru Yang Yong-Guan Zhu Source Type: research
Exceptionally high levels of total mercury in deep-sea sharks of the Southeastern Mediterranean sea over the last ∼ 40 years
Environ Int. 2024 Apr 15;187:108661. doi: 10.1016/j.envint.2024.108661. Online ahead of print.ABSTRACTDeep-sea habitats are currently recognized as a hot spot for mercury (Hg) accumulation from anthropogenic sources, resulting in elevated concentrations of total mercury (THg) in deep-sea megafauna. Among them, deep-sea sharks (Class Chondrichthyes) are characterized by high trophic position and extended longevity and are, therefore, at high risk for mercury contamination. Despite this, sharks are overexploited by fishing activity in increasingly deeper water, worldwide, imposing health risks to human consumption. While it ...
Source: Environment International - April 30, 2024 Category: Environmental Health Authors: Guy Sisma-Ventura Jacob Silverman Yael Segal Hagar Hauzer Maria Abu Khadra Nir Stern Tamar Guy-Haim Barak Herut Source Type: research
Urban indoor gardening enhances immune regulation and diversifies skin microbiota - A placebo-controlled double-blinded intervention study
Environ Int. 2024 Apr 26;187:108705. doi: 10.1016/j.envint.2024.108705. Online ahead of print.ABSTRACTAccording to the hygiene and biodiversity hypotheses, frequent exposure to environmental microbiota, especially through soil contact, diversifies commensal microbiota, enhances immune modulation, and ultimately lowers the risk of immune-mediated diseases. Here we test the underlying assumption of the hygiene and biodiversity hypotheses by instructing volunteers to grow edible plants indoors during the winter season when natural exposure to environmental microbiota is low. The one-month randomized, placebo-controlled double...
Source: Environment International - April 30, 2024 Category: Environmental Health Authors: Mika Saarenp ää Marja I Roslund Noora Nurminen Riikka Puhakka Laura Kummola Olli H Laitinen Heikki Hy öty Aki Sinkkonen Source Type: research
Thermal stress and hospital admissions for cardiorespiratory disease in Brazil
In this study, we explored the association between thermal indices and hospital admissions for circulatory and respiratory diseases in Brazil. We used an extensive dataset spanning 11 years (2008-2018) from the Brazilian Ministry of Health, encompassing a total of 23,791,093 hospitalizations for circulatory and respiratory diseases. We considered four distinct thermal indices-Discomfort Index (DI), Net Effective Temperature (NET), Humidex (H), and Heat Index (HI). We used an extension of the two-stage design with a case time series to assess this relationship. In the first stage, we applied a distributed lag non-linear mod...
Source: Environment International - April 30, 2024 Category: Environmental Health Authors: Weeberb J Requia Francisco Jablinski Castelhano Julia Moore Reizane Maria Damasceno da Silva Mariana Andreotti Dias Source Type: research
Paternal exposures to endocrine-disrupting chemicals induce intergenerational epigenetic influences on offspring: A review
Environ Int. 2024 Apr 24;187:108689. doi: 10.1016/j.envint.2024.108689. Online ahead of print.ABSTRACTEndocrine-disrupting chemicals (EDCs) are ubiquitous in ecological environments and have become a great issue of public health concern since the 1990 s. There is a deep scientific understanding of the toxicity of EDCs. However, recent studies have found that the abnormal physiological functions of the parents caused by EDCs could be transmitted to their unexposed offspring, leading to intergenerational toxicity. We questioned whether sustained epigenetic changes occur through the male germline. In this review, we (1) syste...
Source: Environment International - April 30, 2024 Category: Environmental Health Authors: Yinan Zhang Bingyi Wang Wenhui Sun Guanghui Wang Zhiquan Liu Xiaofang Zhang Jiafeng Ding Yu Han Hangjun Zhang Source Type: research
Quorum sensing bacteria improve microbial networks stability and complexity in wastewater treatment plants
Environ Int. 2024 Apr 24;187:108659. doi: 10.1016/j.envint.2024.108659. Online ahead of print.ABSTRACTQuorum-sensing bacteria (QSB) are crucial factors for microbial communication, yet their ecological role in wastewater treatment plants (WWTPs) remains unclear. Here, we developed a method to identify QSB by comparing 16S rRNA gene sequences. QSB in 388 activated sludge samples collected from 130 WWTPs across China primarily were identified as rare taxa and conditionally rare taxa. A co-occurrence network shared by all sludge communities revealed that QSB exhibited higher average clustering coefficient (0.46) than non-QSB ...
Source: Environment International - April 28, 2024 Category: Environmental Health Authors: Qiuju Liu Deyuan Dong Ying Jin Qian Wang Fuzheng Zhao Linwei Wu Jinfeng Wang Hongqiang Ren Source Type: research
Particle number size distributions and concentrations in transportation environments: a review
Environ Int. 2024 Apr 25;187:108696. doi: 10.1016/j.envint.2024.108696. Online ahead of print.ABSTRACTAmbient air ultrafine particles (UFP, particles with a diameter <100 nm) have gained significant attention in World Health Organization (WHO) air quality guidelines and European legislation. This review explores UFP concentrations and particle number size distributions (PNC-PNSD) in various transportation hotspots, including road traffic, airports, harbors, trains, and urban commuting modes (walking, cycling, bus, tram, and subway). The results highlight the lack of information on personal exposure at harbors and railwa...
Source: Environment International - April 28, 2024 Category: Environmental Health Authors: S Ridolfo F Amato X Querol Source Type: research
Estetrol/drospirenone versus 17 α-ethinylestradiol/drospirenone: An extended one generation test to evaluate the endocrine disruption potential on zebrafish (Danio rerio)
In this study, the endocrine disruptive potential of two mixtures, 17α-ethinylestradiol (EE2), a synthetic oestrogen, or estetrol (E4), a natural oestrogen, with the progestin drospirenone (DRSP) have been characterised in three generations of zebrafish, according to an adapted Medaka Extended One Generation Reproduction Test. Zebrafish (Danio rerio) were exposed to a range of concentrations of EE2/DRSP and E4/DRSP (∼1×, ∼3×, ∼10× and ∼30× predicted environmental concentration, PEC). Survival, growth, hatching success, fecundity, fertilisation success, vitellogenin (VTG), gonad histopathology, sex differentiat...
Source: Environment International - April 28, 2024 Category: Environmental Health Authors: S ébastien Baekelandt Antoine Bouchat Nathalie Leroux Jean-Baptiste Robert Laura Burattin Emmanuel Cishibanji J érôme Lambert C éline Gérard C éline Delierneux Patrick Kestemont Source Type: research
Low-level PM < sub > 2.5 < /sub > induces the occurrence of early pulmonary injury by regulating circ_0092363
Environ Int. 2024 Apr 25;187:108700. doi: 10.1016/j.envint.2024.108700. Online ahead of print.ABSTRACTThe significant correlation between particulate matter with aerodynamic diameters of ≤ 2.5 µm (PM2.5) and the high morbidity and mortality of respiratory diseases has become the consensus of the research. Epidemiological studies have clearly pointed out that there is no safe concentration of PM2.5, and mechanism studies have also shown that exposure to PM2.5 will first cause pulmonary inflammation. Therefore, the purpose of this study is to explore the mechanism of early lung injury induced by low-level PM2.5 from the p...
Source: Environment International - April 28, 2024 Category: Environmental Health Authors: Jie Xu Mengyao Ni Jing Wang Jiahao Zhu Guolei Niu Jiajing Cui Xiaobo Li Qingtao Meng Rui Chen Source Type: research
