Diesel exhaust and respiratory dust exposure in miners and chronic obstructive pulmonary disease (COPD) mortality in DEMS II
CONCLUSIONS: Our findings, based on data from a cohort of nonmetal miners, are suggestive of an increased risk of COPD mortality associated with REC and RD, as well as evidence of survivor bias in this population leading to negative associations between cumulative exposures and COPD mortality in traditional regression analysis.PMID:38422874 | DOI:10.1016/j.envint.2024.108528 (Source: Environment International)
Source: Environment International - February 29, 2024 Category: Environmental Health Authors: Andreas M Neophytou Jacqueline M Ferguson Sadie Costello Sally Picciotto John R Balmes Stella Koutros Debra T Silverman Ellen A Eisen Source Type: research
Bacterial communities of planktonic bacteria and mature biofilm in service lines and premise plumbing of a Megacity: Composition, Diversity, and influencing factors
In this study, the bacterial communities of water and biofilm were explored, with a special focus on the lifetime development of biofilm communities and their key influencing factors. The 16S rRNA gene sequencing results showed that both the planktonic bacteria and biofilm were dominated by Proteobacteria. Among the 15,084 observed amplicon sequence variants (ASVs), the 33 core ASVs covered 72.8 %, while the 12 shared core ASVs accounted for 62.2 % of the total sequences. Remarkably, it was found that the species richness and diversity of biofilm communities correlated with pipe age. The relative abundance of ASV2 (f_Sphin...
Source: Environment International - February 29, 2024 Category: Environmental Health Authors: Anran Ren Mingchen Yao Jiaxing Fang Zihan Dai Xiaoming Li Walter van der Meer Gertjan Medema Joan B Rose Gang Liu Source Type: research
The size-dependence and reversibility of polystyrene nanoplastics-induced lipid accumulation in mice: Possible roles of lysosomes
In this study, the effects of long-term exposure to environmentally relevant doses of polystyrene nanoplastics (PS-NPs) on lipid accumulation were investigated in terms of autophagy and lysosomal mechanisms. The findings indicated that hepatic lipid accumulation was more pronounced in mice exposed to 100 nm PS-NPs compared to 500 nm PS-NPs. This effect was effectively alleviated after 50 days of self-recovery for 100 nm and 500 nm PS-NPs exposure. Mechanistically, although PS-NPs exposure activated autophagosome formation through ERK (mitogen-activated protein kinase 1)/mTOR (mechanistic target of rapamycin kinase) signali...
Source: Environment International - February 29, 2024 Category: Environmental Health Authors: Yan-Yang Lu Lu Lu Hong-Yun Ren Weizhen Hua Nengxing Zheng Fu-Yi Huang Jiani Wang Meiping Tian Qingyu Huang Source Type: research
Who is more vulnerable to effects of long-term exposure to air pollution on COVID-19 hospitalisation?
CONCLUSIONS: Long-term exposure to air pollution had a larger synergistic effect on COVID-19 hospitalisation for males and those with lower individual- and area-level socioeconomic status.PMID:38422877 | DOI:10.1016/j.envint.2024.108530 (Source: Environment International)
Source: Environment International - February 29, 2024 Category: Environmental Health Authors: Otavio Ranzani Anna Alari Sergio Olmos Carles Mil à Alex Rico Xavier Basaga ña Payam Dadvand Talita Duarte-Salles Francesco Forastiere Mark Nieuwenhuijsen Rosa M Vivanco-Hidalgo Cathryn Tonne Source Type: research
Quantifying source contributions to ambient NH < sub > 3 < /sub > using Geo-AI with time lag and parcel tracking functions
This study represents a pioneering effort in the application of a novel geospatial-artificial intelligence (Geo-AI) base model with parcel tracking functions. This innovative approach seamlessly integrates various machine learning algorithms and geographic predictor variables to estimate NH3 concentrations, marking the first instance of such a comprehensive methodology. The Shapley additive explanation (SHAP) was used to further analyze source contribution of NH3 with domain knowledge. From 2016 to 2018, Taichung's hourly average NH3 values were predicted with total variance up to 96%. SHAP values revealed that waterbody, ...
Source: Environment International - February 27, 2024 Category: Environmental Health Authors: Chih-Da Wu Jun-Jie Zhu Chin-Yu Hsu Ruei-Hao Shie Source Type: research
Neurodegenerative effects of air pollutant Particles: Biological mechanisms implicated for Early-Onset Alzheimer's disease
CONCLUSIONS: This study provides insights into the mechanistic links between inflammation and oxidative stress to pollutant particle-induced AD pathologies, with magnetite apparently inducing the most pathological effects. No exacerbation of the effects was observed in the AD-predisposed model when compared to the wild-type, indicating a particle-induced neurodegeneration that is independent of disease state.PMID:38412566 | DOI:10.1016/j.envint.2024.108512 (Source: Environment International)
Source: Environment International - February 27, 2024 Category: Environmental Health Authors: Cindy Gunawan Charlotte Fleming Peter J Irga Roong Jien Wong Rose Amal Fraser R Torpy S Mojtaba Golzan Kristine C McGrath Source Type: research
Quantifying source contributions to ambient NH < sub > 3 < /sub > using Geo-AI with time lag and parcel tracking functions
This study represents a pioneering effort in the application of a novel geospatial-artificial intelligence (Geo-AI) base model with parcel tracking functions. This innovative approach seamlessly integrates various machine learning algorithms and geographic predictor variables to estimate NH3 concentrations, marking the first instance of such a comprehensive methodology. The Shapley additive explanation (SHAP) was used to further analyze source contribution of NH3 with domain knowledge. From 2016 to 2018, Taichung's hourly average NH3 values were predicted with total variance up to 96%. SHAP values revealed that waterbody, ...
Source: Environment International - February 27, 2024 Category: Environmental Health Authors: Chih-Da Wu Jun-Jie Zhu Chin-Yu Hsu Ruei-Hao Shie Source Type: research
Neurodegenerative effects of air pollutant Particles: Biological mechanisms implicated for Early-Onset Alzheimer's disease
CONCLUSIONS: This study provides insights into the mechanistic links between inflammation and oxidative stress to pollutant particle-induced AD pathologies, with magnetite apparently inducing the most pathological effects. No exacerbation of the effects was observed in the AD-predisposed model when compared to the wild-type, indicating a particle-induced neurodegeneration that is independent of disease state.PMID:38412566 | DOI:10.1016/j.envint.2024.108512 (Source: Environment International)
Source: Environment International - February 27, 2024 Category: Environmental Health Authors: Cindy Gunawan Charlotte Fleming Peter J Irga Roong Jien Wong Rose Amal Fraser R Torpy S Mojtaba Golzan Kristine C McGrath Source Type: research
Novel mechanism by which extracellular vesicles derived from Lactobacillus murinus alleviates deoxynivalenol-induced intestinal barrier disruption
This study was aim to explore whether gut microbiota is involved in DON-induced intestinal toxicity as well as to reveal effect of probiotics derived from gut microbiota in protecting intestinal barrier and to elucidate mechanism. We found that DON caused disturbed gut microbiota, particularly Lactobacillus murinus (L. murinus) deficiency. DON enhanced M1 macrophage polarization and decreased tight junction protein expression. Microbiota transplantation experiments showed that transfer of DON-disrupted microbiota to healthy mice resulted in delivery of DON-induced intestinal toxicity. Besides, DON lost its damaging effect ...
Source: Environment International - February 26, 2024 Category: Environmental Health Authors: Jinping Fan Yuhan Zhang Minyu Zuo Shixuan Ding Jingjing Li Shengkai Feng Yingping Xiao Shiyu Tao Source Type: research
Novel mechanism by which extracellular vesicles derived from Lactobacillus murinus alleviates deoxynivalenol-induced intestinal barrier disruption
This study was aim to explore whether gut microbiota is involved in DON-induced intestinal toxicity as well as to reveal effect of probiotics derived from gut microbiota in protecting intestinal barrier and to elucidate mechanism. We found that DON caused disturbed gut microbiota, particularly Lactobacillus murinus (L. murinus) deficiency. DON enhanced M1 macrophage polarization and decreased tight junction protein expression. Microbiota transplantation experiments showed that transfer of DON-disrupted microbiota to healthy mice resulted in delivery of DON-induced intestinal toxicity. Besides, DON lost its damaging effect ...
Source: Environment International - February 26, 2024 Category: Environmental Health Authors: Jinping Fan Yuhan Zhang Minyu Zuo Shixuan Ding Jingjing Li Shengkai Feng Yingping Xiao Shiyu Tao Source Type: research
Combined magnetic biochar and ryegrass enhanced the remediation effect of soils contaminated with multiple heavy metals
Environ Int. 2024 Feb 13;185:108498. doi: 10.1016/j.envint.2024.108498. Online ahead of print.ABSTRACTBiochar is a very promising material for soil remediation. However, most studies mainly focus on the adsorption ability of biochar on one heavy metal, which is difficult to evaluate the actual remediation effect since soils were contaminated with multiple heavy metals. In order to improve the soil remediation efficiency, we used the joint remediation method of magnetically modified biochar and ryegrass to remediate the soil polluted by compound heavy metals (chromium, nickel, copper, zinc, arsenic and cadmium), and evaluat...
Source: Environment International - February 25, 2024 Category: Environmental Health Authors: Xuening Li Ruipu Li Mengqi Zhan Qian Hou Haoyu Zhang Guangqi Wu Liqun Ding Xiaofei Lv Yan Xu Source Type: research
Combined magnetic biochar and ryegrass enhanced the remediation effect of soils contaminated with multiple heavy metals
Environ Int. 2024 Feb 13;185:108498. doi: 10.1016/j.envint.2024.108498. Online ahead of print.ABSTRACTBiochar is a very promising material for soil remediation. However, most studies mainly focus on the adsorption ability of biochar on one heavy metal, which is difficult to evaluate the actual remediation effect since soils were contaminated with multiple heavy metals. In order to improve the soil remediation efficiency, we used the joint remediation method of magnetically modified biochar and ryegrass to remediate the soil polluted by compound heavy metals (chromium, nickel, copper, zinc, arsenic and cadmium), and evaluat...
Source: Environment International - February 25, 2024 Category: Environmental Health Authors: Xuening Li Ruipu Li Mengqi Zhan Qian Hou Haoyu Zhang Guangqi Wu Liqun Ding Xiaofei Lv Yan Xu Source Type: research
Maternal nanoplastic ingestion induces an increase in offspring body weight through altered lipid species and microbiota
In this study, we examined whether environmental nanoplastic (NP) pollutants can act as environmental obesogens using mouse models exposed to NPs derived from polystyrene and polypropylene, which are abundant in the environment. We found abnormal weight gain in the progeny until 6 weeks of age following the oral administration of NPs to the mother during gestation and lactation. Through a series of experiments involving multi-omic analyses, we have demonstrated that NP-induced weight gain is caused by alterations in the lipid composition (lysophosphatidylcholine/phosphatidylcholine ratio) of maternal breast milk and he gut...
Source: Environment International - February 24, 2024 Category: Environmental Health Authors: Bohyeon Jeong Ji-Sun Kim A Ra Kwon Jangjae Lee Subin Park Jahong Koo Wang Sik Lee Jeong Yeob Baek Won-Ho Shin Jung-Sook Lee Jinyoung Jeong Won Kon Kim Cho-Rok Jung Nam-Soon Kim Sung-Hee Cho Da Yong Lee Source Type: research
Biotransformation of roxarsone by earthworms and subsequent risk of soil arsenic release: The role of gut bacteria
In this study, the changes in As speciation, bacterial ABGs, and communities were analyzed in a ROX-contaminated soil (50 mg/kg As in ROX form) containing the earthworm Eisenia feotida. (RE vs. R treatment). After 56 d, earthworms reduced the levels of both ROX and total As by 59 % and 17 %, respectively. The available As content was 10 % lower in the RE than in R treatment. Under ROX stress, the total ABG abundance was upregulated in both earthworm gut and soil, with synergistic effects observed following RE treatment. Besides, the enrichment of arsM and arsB genes in earthworm gut suggested that gut bacteria may facilita...
Source: Environment International - February 24, 2024 Category: Environmental Health Authors: Yizhao Wu Song-Ge Deng Yunxiang Xu Yifan Zhang Puguo Hao Qi Zhao Jibao Jiang Yinsheng Li Source Type: research
Evaluating the sensitivity of mortality attributable to pollution to modeling Choices: A case study for Colorado
Environ Int. 2024 Jan 3;185:108416. doi: 10.1016/j.envint.2024.108416. Online ahead of print.ABSTRACTWe evaluated the sensitivity of estimated PM2.5 and NO2 health impacts to varying key input parameters and assumptions including: 1) the spatial scale at which impacts are estimated, 2) using either a single concentration-response function (CRF) or using racial/ethnic group specific CRFs from the same epidemiologic study, 3) assigning exposure to residents based on home, instead of home and work locations for the state of Colorado. We found that the spatial scale of the analysis influences the magnitude of NO2, but not PM2....
Source: Environment International - February 23, 2024 Category: Environmental Health Authors: Priyanka N deSouza Susan Anenberg Neal Fann Lisa M McKenzie Elizabeth Chan Ananya Roy Jose L Jimenez William Raich Henry Roman Patrick L Kinney Source Type: research
