Biotransformation of roxarsone by earthworms and subsequent risk of soil arsenic release: The role of gut bacteria
In this study, the changes in As speciation, bacterial ABGs, and communities were analyzed in a ROX-contaminated soil (50 mg/kg As in ROX form) containing the earthworm Eisenia feotida. (RE vs. R treatment). After 56 d, earthworms reduced the levels of both ROX and total As by 59 % and 17 %, respectively. The available As content was 10 % lower in the RE than in R treatment. Under ROX stress, the total ABG abundance was upregulated in both earthworm gut and soil, with synergistic effects observed following RE treatment. Besides, the enrichment of arsM and arsB genes in earthworm gut suggested that gut bacteria may facilita...
Source: Environment International - February 24, 2024 Category: Environmental Health Authors: Yizhao Wu Song-Ge Deng Yunxiang Xu Yifan Zhang Puguo Hao Qi Zhao Jibao Jiang Yinsheng Li Source Type: research
Evaluating the sensitivity of mortality attributable to pollution to modeling Choices: A case study for Colorado
Environ Int. 2024 Jan 3;185:108416. doi: 10.1016/j.envint.2024.108416. Online ahead of print.ABSTRACTWe evaluated the sensitivity of estimated PM2.5 and NO2 health impacts to varying key input parameters and assumptions including: 1) the spatial scale at which impacts are estimated, 2) using either a single concentration-response function (CRF) or using racial/ethnic group specific CRFs from the same epidemiologic study, 3) assigning exposure to residents based on home, instead of home and work locations for the state of Colorado. We found that the spatial scale of the analysis influences the magnitude of NO2, but not PM2....
Source: Environment International - February 23, 2024 Category: Environmental Health Authors: Priyanka N deSouza Susan Anenberg Neal Fann Lisa M McKenzie Elizabeth Chan Ananya Roy Jose L Jimenez William Raich Henry Roman Patrick L Kinney Source Type: research
Circ_0008657 regulates lung DNA damage induced by hexavalent chromium through the miR-203a-3p/ATM axis
Environ Int. 2024 Feb 19;185:108515. doi: 10.1016/j.envint.2024.108515. Online ahead of print.ABSTRACTHexavalent chromium [Cr (VI)] is an important environmental pollutant and may cause lung injury when inhaled into the human body. Cr (VI) is genotoxic and can cause DNA damage, although the underlying epigenetic mechanisms remain unclear. To simulate the real-life workplace exposure to Cr (VI), we used a novel exposure dose calculation method. We evaluated the effect of Cr (VI) on DNA damage in human bronchial epithelial cells (16HBE and BEAS-2B) by calculating the equivalent real-time exposure dose of Cr (VI) (0 to 10 μM...
Source: Environment International - February 23, 2024 Category: Environmental Health Authors: Wei Chen Zehao Chen Yangyang Jia Yaozheng Guo Liting Zheng Shuwei Yao Yueting Shao Meizhen Li Rulin Mao Yiguo Jiang Source Type: research
Proteome changes in larval zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) exposed to ( ±) anatoxin-a
Environ Int. 2024 Feb 18;185:108514. doi: 10.1016/j.envint.2024.108514. Online ahead of print.ABSTRACTAnatoxin-a and its analogues are potent neurotoxins produced by several genera of cyanobacteria. Due in part to its high toxicity and potential presence in drinking water, these toxins pose threats to public health, companion animals and the environment. It primarily exerts toxicity as a cholinergic agonist, with high affinity at neuromuscular junctions, but molecular mechanisms by which it elicits toxicological responses are not fully understood. To advance understanding of this cyanobacteria, proteomic characterization (...
Source: Environment International - February 23, 2024 Category: Environmental Health Authors: Laura M Langan Lea M Lovin Raegyn B Taylor Kendall R Scarlett C Kevin Chambliss Saurabh Chatterjee J Thad Scott Bryan W Brooks Source Type: research
An integrated meta-omics approach reveals the different response mechanisms of two anammox bacteria towards fluoroquinolone antibiotics
This study investigated the effects of ciprofloxacin, ofloxacin and their mixture at concentrations detected in livestock wastewater on two key anammox species in membrane bioreactors. It was found 20 μg/L FQs promoted nitrogen removal efficiency and community stability, and42-51 % of FQs were removed simultaneously. Integrated meta-omics analysis revealed varied gene expression patterns between the two dominant AnAOB, Candidatus Brocadia sapporoensis (B AnAOB) and Candidatus Kuenenia stuttgartiensis (K AnAOB). The nitrogen metabolic processes were bolstered in B AnAOB, while those involved in anammox pathway of K AnAOB w...
Source: Environment International - February 23, 2024 Category: Environmental Health Authors: Xuejiao Qiao Lingyun Ding Fang Fang Chenkun Fu Ruqian Wei Yizhen Chen Sihan Zheng Xisong Wang Yan Yan Kai Yang Nan Xu Huchun Tao Ke Yu Lijuan Zhang Source Type: research
Evaluating the sensitivity of mortality attributable to pollution to modeling Choices: A case study for Colorado
Environ Int. 2024 Jan 3;185:108416. doi: 10.1016/j.envint.2024.108416. Online ahead of print.ABSTRACTWe evaluated the sensitivity of estimated PM2.5 and NO2 health impacts to varying key input parameters and assumptions including: 1) the spatial scale at which impacts are estimated, 2) using either a single concentration-response function (CRF) or using racial/ethnic group specific CRFs from the same epidemiologic study, 3) assigning exposure to residents based on home, instead of home and work locations for the state of Colorado. We found that the spatial scale of the analysis influences the magnitude of NO2, but not PM2....
Source: Environment International - February 23, 2024 Category: Environmental Health Authors: Priyanka N deSouza Susan Anenberg Neal Fann Lisa M McKenzie Elizabeth Chan Ananya Roy Jose L Jimenez William Raich Henry Roman Patrick L Kinney Source Type: research
Circ_0008657 regulates lung DNA damage induced by hexavalent chromium through the miR-203a-3p/ATM axis
Environ Int. 2024 Feb 19;185:108515. doi: 10.1016/j.envint.2024.108515. Online ahead of print.ABSTRACTHexavalent chromium [Cr (VI)] is an important environmental pollutant and may cause lung injury when inhaled into the human body. Cr (VI) is genotoxic and can cause DNA damage, although the underlying epigenetic mechanisms remain unclear. To simulate the real-life workplace exposure to Cr (VI), we used a novel exposure dose calculation method. We evaluated the effect of Cr (VI) on DNA damage in human bronchial epithelial cells (16HBE and BEAS-2B) by calculating the equivalent real-time exposure dose of Cr (VI) (0 to 10 μM...
Source: Environment International - February 23, 2024 Category: Environmental Health Authors: Wei Chen Zehao Chen Yangyang Jia Yaozheng Guo Liting Zheng Shuwei Yao Yueting Shao Meizhen Li Rulin Mao Yiguo Jiang Source Type: research
Proteome changes in larval zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) exposed to ( ±) anatoxin-a
Environ Int. 2024 Feb 18;185:108514. doi: 10.1016/j.envint.2024.108514. Online ahead of print.ABSTRACTAnatoxin-a and its analogues are potent neurotoxins produced by several genera of cyanobacteria. Due in part to its high toxicity and potential presence in drinking water, these toxins pose threats to public health, companion animals and the environment. It primarily exerts toxicity as a cholinergic agonist, with high affinity at neuromuscular junctions, but molecular mechanisms by which it elicits toxicological responses are not fully understood. To advance understanding of this cyanobacteria, proteomic characterization (...
Source: Environment International - February 23, 2024 Category: Environmental Health Authors: Laura M Langan Lea M Lovin Raegyn B Taylor Kendall R Scarlett C Kevin Chambliss Saurabh Chatterjee J Thad Scott Bryan W Brooks Source Type: research
An integrated meta-omics approach reveals the different response mechanisms of two anammox bacteria towards fluoroquinolone antibiotics
This study investigated the effects of ciprofloxacin, ofloxacin and their mixture at concentrations detected in livestock wastewater on two key anammox species in membrane bioreactors. It was found 20 μg/L FQs promoted nitrogen removal efficiency and community stability, and42-51 % of FQs were removed simultaneously. Integrated meta-omics analysis revealed varied gene expression patterns between the two dominant AnAOB, Candidatus Brocadia sapporoensis (B AnAOB) and Candidatus Kuenenia stuttgartiensis (K AnAOB). The nitrogen metabolic processes were bolstered in B AnAOB, while those involved in anammox pathway of K AnAOB w...
Source: Environment International - February 23, 2024 Category: Environmental Health Authors: Xuejiao Qiao Lingyun Ding Fang Fang Chenkun Fu Ruqian Wei Yizhen Chen Sihan Zheng Xisong Wang Yan Yan Kai Yang Nan Xu Huchun Tao Ke Yu Lijuan Zhang Source Type: research
Photoaging of biodegradable nanoplastics regulates their toxicity to aquatic insects (Chironomus kiinensis) by impairing gut and disrupting intestinal microbiota
This study provides insights into the effects of biodegradable NPs on aquatic insects and highlights the importance of considering biodegradable nanoplastic aging in risk assessments.PMID:38382402 | DOI:10.1016/j.envint.2024.108483 (Source: Environment International)
Source: Environment International - February 21, 2024 Category: Environmental Health Authors: Jie Zhang Xinghui Xia Wei Huang Yang Li Xiaohan Lin Yao Li Zhifeng Yang Source Type: research
Cadmium exposure causes transcriptomic dysregulation in adipose tissue and associated shifts in serum metabolites
In this study, we found that Cd accumulates in adipose tissues of mice subjected to Cd exposure. Intriguingly, Cd exposure in itself did not induce significant alterations in the adipose tissue under normal conditions. However, when subjected to cold stimulation, several notable changes were observed in the mice exposed to Cd, including a reduction in the drop of body temperature, a decrease in the size of inguinal white adipose tissue (WAT), and an increase in the expression of thermogenic genes UCP1 and PRDM16. These results indicate that Cd exposure might enhance the responsiveness of adipose tissue to external stimuli ...
Source: Environment International - February 21, 2024 Category: Environmental Health Authors: Yi Zhu Ping Cheng Junxuan Peng Sishuo Liu Jie Xiang Dandan Xu Yuan Chen Zhijian Chen Xiaofeng Wang Chi Luo Peiwei Xu Jinghao Sheng Source Type: research
National-scale investigation reveals the dominant role of phyllosphere fungal pathogens in sorghum yield loss
Environ Int. 2024 Feb 17;185:108511. doi: 10.1016/j.envint.2024.108511. Online ahead of print.ABSTRACTFungal plant pathogens threaten crop production and sustainable agricultural development. However, the environmental factors driving their diversity and nationwide biogeographic model remain elusive, impacting our capacity to predict their changes under future climate scenarios. Here, we analyzed potential fungal plant pathogens from 563 samples collected from 57 agricultural fields across China. Over 28.0% of fungal taxa in the phyllosphere were identified as potential plant pathogens, compared to 22.3% in the rhizosphere...
Source: Environment International - February 21, 2024 Category: Environmental Health Authors: Peixin Ren Anqi Sun Xiaoyan Jiao Qing-Lin Chen Fangfang Li Ji-Zheng He Hang-Wei Hu Source Type: research
Photoaging of biodegradable nanoplastics regulates their toxicity to aquatic insects (Chironomus kiinensis) by impairing gut and disrupting intestinal microbiota
This study provides insights into the effects of biodegradable NPs on aquatic insects and highlights the importance of considering biodegradable nanoplastic aging in risk assessments.PMID:38382402 | DOI:10.1016/j.envint.2024.108483 (Source: Environment International)
Source: Environment International - February 21, 2024 Category: Environmental Health Authors: Jie Zhang Xinghui Xia Wei Huang Yang Li Xiaohan Lin Yao Li Zhifeng Yang Source Type: research
Cadmium exposure causes transcriptomic dysregulation in adipose tissue and associated shifts in serum metabolites
In this study, we found that Cd accumulates in adipose tissues of mice subjected to Cd exposure. Intriguingly, Cd exposure in itself did not induce significant alterations in the adipose tissue under normal conditions. However, when subjected to cold stimulation, several notable changes were observed in the mice exposed to Cd, including a reduction in the drop of body temperature, a decrease in the size of inguinal white adipose tissue (WAT), and an increase in the expression of thermogenic genes UCP1 and PRDM16. These results indicate that Cd exposure might enhance the responsiveness of adipose tissue to external stimuli ...
Source: Environment International - February 21, 2024 Category: Environmental Health Authors: Yi Zhu Ping Cheng Junxuan Peng Sishuo Liu Jie Xiang Dandan Xu Yuan Chen Zhijian Chen Xiaofeng Wang Chi Luo Peiwei Xu Jinghao Sheng Source Type: research
National-scale investigation reveals the dominant role of phyllosphere fungal pathogens in sorghum yield loss
Environ Int. 2024 Feb 17;185:108511. doi: 10.1016/j.envint.2024.108511. Online ahead of print.ABSTRACTFungal plant pathogens threaten crop production and sustainable agricultural development. However, the environmental factors driving their diversity and nationwide biogeographic model remain elusive, impacting our capacity to predict their changes under future climate scenarios. Here, we analyzed potential fungal plant pathogens from 563 samples collected from 57 agricultural fields across China. Over 28.0% of fungal taxa in the phyllosphere were identified as potential plant pathogens, compared to 22.3% in the rhizosphere...
Source: Environment International - February 21, 2024 Category: Environmental Health Authors: Peixin Ren Anqi Sun Xiaoyan Jiao Qing-Lin Chen Fangfang Li Ji-Zheng He Hang-Wei Hu Source Type: research
