Inconsistencies in the EU regulatory risk assessment of PFAS call for readjustment
Environ Int. 2024 Mar 29;186:108614. doi: 10.1016/j.envint.2024.108614. Online ahead of print.ABSTRACTRecognition of per- and polyfluoroalkyl substances (PFAS) as widespread environmental pollutants and a consequent risk to human health, has recently made the European Union (EU) adopt several regulatory measures for their management. The coherence of these measures is challenged by the diversity and the ubiquitous occurrence of PFAS, which also complicates the EU's endeavor to advance justified, harmonized, and transparent approaches in the regulatory assessment of chemical risks. Our study critically reviews the European ...
Source: Environment International - April 7, 2024 Category: Environmental Health Authors: Jussi Reinikainen Elodie Bouhoulle Jaana Sorvari Source Type: research

Plastic footprint deteriorates dryland carbon footprint across soil-plant-atmosphere continuum
Environ Int. 2024 Apr 4;186:108632. doi: 10.1016/j.envint.2024.108632. Online ahead of print.ABSTRACTPlastic fragments are widely found in the soil profile of terrestrial ecosystems, forming plastic footprint and posing increasing threat to soil functionality and carbon (C) footprint. It is unclear how plastic footprint affects C cycling, and in particularly permanent C sequestration. Integrated field observations (including 13C labelling) were made using polyethylene and polylactic acid plastic fragments (low-, medium- and high-concentrations as intensifying footprint) landfilling in soil, to track C flow along soil-plant...
Source: Environment International - April 7, 2024 Category: Environmental Health Authors: Meng-Ying Li Wei Wang Yue Ma Yinglong Chen Hong-Yan Tao Ze-Ying Zhao Peng-Yang Wang Li Zhu Baoluo Ma Yun-Li Xiao Shi-Sheng Li Muhammad Ashraf Wen-Ying Wang Xiao-Bin Xiong Ying Zhu Jin-Lin Zhang Momena Irum Ya-Jie Song Levis Kavagi You-Cai Xiong Source Type: research

First trimester plasma PER- AND Polyfluoroalkyl Substances (PFAS) and blood pressure trajectories across the second and third trimesters of pregnanacy
CONCLUSION: Early pregnancy plasma PFOS concentrations were associated with altered BP trajectory in pregnancy, which may impact future cardiovascular health of the mother.PMID:38583297 | DOI:10.1016/j.envint.2024.108628 (Source: Environment International)
Source: Environment International - April 7, 2024 Category: Environmental Health Authors: Jordan A Burdeau Briana J K Stephenson Izzuddin M Aris Emma V Preston Marie-France Hivert Emily Oken Shruthi Mahalingaiah Jorge E Chavarro Antonia M Calafat Sheryl L Rifas-Shiman Ami R Zota Tamarra James-Todd Source Type: research

Photochemical evolution of the molecular composition of dissolved organic carbon and dissolved brown carbon from wood smoldering
Environ Int. 2024 Apr 3;186:108629. doi: 10.1016/j.envint.2024.108629. Online ahead of print.ABSTRACTRecently, extreme wildfires occur frequently around the world and emit substantial brown carbon (BrC) into the atmosphere, whereas the molecular compositions and photochemical evolution of BrC remain poorly understood. In this work, primary smoke aerosols were generated from wood smoldering, and secondary smoke aerosols were formed by the OH radical photooxidation in an oxidation flow reactor, where both primary and secondary smoke samples were collected on filters. After solvent extraction of filter samples, the molecular ...
Source: Environment International - April 6, 2024 Category: Environmental Health Authors: Ranran Zhao Weixiong Zhao Yong Dai Jiacheng Zhou Xuezhe Xu Feng Wang Qixing Zhang Yongming Zhang Weijun Zhang Source Type: research

Commercial compost amendments inhibit the bioavailability and plant uptake of per- and polyfluoroalkyl substances in soil-porewater-lettuce systems
This study examined how compost affects the bioavailability and uptake of eight PFAS (two ethers, three fluorotelomer sulfonates, and three perfluorosulfonates) by lettuce (Lactuca sativa) grown in commercial organic compost-amended, PFAS spiked soils. After 50 days of greenhouse experiment, PFAS uptake by lettuce decreased (by up to 90.5 %) with the increasing compost amendment ratios (0-20 %, w/w), consistent with their decreased porewater concentrations (by 30.7-86.3 %) in compost-amended soils. Decreased bioavailability of PFAS was evidenced by the increased in-situ soil-porewater distribution coefficients (Kd) (by fac...
Source: Environment International - April 6, 2024 Category: Environmental Health Authors: Yuanbo Li Yue Zhi Rebecca Weed Stephen W Broome Detlef R U Knappe Owen W Duckworth Source Type: research

Corrigendum to "Ultra-processed and fast food consumption, exposure to phthalates during pregnancy, and socioeconomic disparities in phthalate exposures" [Environ. Int. 183 (2024) 108427]
Environ Int. 2024 Apr 5:108623. doi: 10.1016/j.envint.2024.108623. Online ahead of print.NO ABSTRACTPMID:38582681 | DOI:10.1016/j.envint.2024.108623 (Source: Environment International)
Source: Environment International - April 6, 2024 Category: Environmental Health Authors: Brennan H Baker Melissa M Melough Alison G Paquette Emily S Barrett Drew B Day Kurunthachalam Kannan Ruby H N Nguyen Nicole R Bush Kaja Z LeWinn Kecia N Carroll Shanna H Swan Qi Zhao Sheela Sathyanarayana Source Type: research

Corrigendum to "A genome-wide association study of 24-hour urinary excretion of endocrine disrupting chemicals" [Environ. Int., A Genome-Wide Association Study of 24-Hour Urinary Excretion of Endocrine Disrupting Chemicals 183 (2024) 108396]
Environ Int. 2024 Apr 5:108622. doi: 10.1016/j.envint.2024.108622. Online ahead of print.NO ABSTRACTPMID:38582682 | DOI:10.1016/j.envint.2024.108622 (Source: Environment International)
Source: Environment International - April 6, 2024 Category: Environmental Health Authors: Xueling Lu Thomas P van der Meer Zoha Kamali Martijn van Faassen Ido P Kema Andr é P van Beek Xijin Xu Xia Huo Alireza Ani Lifelines Cohort Study Ilja M Nolte Bruce H R Wolffenbuttel Jana V van Vliet-Ostaptchouk Harold Snieder Source Type: research

Photochemical evolution of the molecular composition of dissolved organic carbon and dissolved brown carbon from wood smoldering
Environ Int. 2024 Apr 3;186:108629. doi: 10.1016/j.envint.2024.108629. Online ahead of print.ABSTRACTRecently, extreme wildfires occur frequently around the world and emit substantial brown carbon (BrC) into the atmosphere, whereas the molecular compositions and photochemical evolution of BrC remain poorly understood. In this work, primary smoke aerosols were generated from wood smoldering, and secondary smoke aerosols were formed by the OH radical photooxidation in an oxidation flow reactor, where both primary and secondary smoke samples were collected on filters. After solvent extraction of filter samples, the molecular ...
Source: Environment International - April 6, 2024 Category: Environmental Health Authors: Ranran Zhao Weixiong Zhao Yong Dai Jiacheng Zhou Xuezhe Xu Feng Wang Qixing Zhang Yongming Zhang Weijun Zhang Source Type: research

Commercial compost amendments inhibit the bioavailability and plant uptake of per- and polyfluoroalkyl substances in soil-porewater-lettuce systems
This study examined how compost affects the bioavailability and uptake of eight PFAS (two ethers, three fluorotelomer sulfonates, and three perfluorosulfonates) by lettuce (Lactuca sativa) grown in commercial organic compost-amended, PFAS spiked soils. After 50 days of greenhouse experiment, PFAS uptake by lettuce decreased (by up to 90.5 %) with the increasing compost amendment ratios (0-20 %, w/w), consistent with their decreased porewater concentrations (by 30.7-86.3 %) in compost-amended soils. Decreased bioavailability of PFAS was evidenced by the increased in-situ soil-porewater distribution coefficients (Kd) (by fac...
Source: Environment International - April 6, 2024 Category: Environmental Health Authors: Yuanbo Li Yue Zhi Rebecca Weed Stephen W Broome Detlef R U Knappe Owen W Duckworth Source Type: research

Corrigendum to "Ultra-processed and fast food consumption, exposure to phthalates during pregnancy, and socioeconomic disparities in phthalate exposures" [Environ. Int. 183 (2024) 108427]
Environ Int. 2024 Apr 5:108623. doi: 10.1016/j.envint.2024.108623. Online ahead of print.NO ABSTRACTPMID:38582681 | DOI:10.1016/j.envint.2024.108623 (Source: Environment International)
Source: Environment International - April 6, 2024 Category: Environmental Health Authors: Brennan H Baker Melissa M Melough Alison G Paquette Emily S Barrett Drew B Day Kurunthachalam Kannan Ruby H N Nguyen Nicole R Bush Kaja Z LeWinn Kecia N Carroll Shanna H Swan Qi Zhao Sheela Sathyanarayana Source Type: research

Corrigendum to "A genome-wide association study of 24-hour urinary excretion of endocrine disrupting chemicals" [Environ. Int., A Genome-Wide Association Study of 24-Hour Urinary Excretion of Endocrine Disrupting Chemicals 183 (2024) 108396]
Environ Int. 2024 Apr 5:108622. doi: 10.1016/j.envint.2024.108622. Online ahead of print.NO ABSTRACTPMID:38582682 | DOI:10.1016/j.envint.2024.108622 (Source: Environment International)
Source: Environment International - April 6, 2024 Category: Environmental Health Authors: Xueling Lu Thomas P van der Meer Zoha Kamali Martijn van Faassen Ido P Kema Andr é P van Beek Xijin Xu Xia Huo Alireza Ani Lifelines Cohort Study Ilja M Nolte Bruce H R Wolffenbuttel Jana V van Vliet-Ostaptchouk Harold Snieder Source Type: research

Global health impacts of ambient fine particulate pollution associated with climate variability
Environ Int. 2024 Mar 26;186:108587. doi: 10.1016/j.envint.2024.108587. Online ahead of print.ABSTRACTAir pollution is a key global environmental problem raising human health concern. It is essential to comprehensively assess the long-term characteristics of air pollution and the resultant health impacts. We first assessed the global trends of fine particulate matter (PM2.5) during 1980-2020 using a monthly global PM2.5 reanalysis dataset, and evaluated their association with three types of climate variability including El Niño-Southern Oscillation, Indian Ocean Dipole and North Atlantic Oscillation. We then estimated PM2...
Source: Environment International - April 5, 2024 Category: Environmental Health Authors: S H L Yim Y Li T Huang J T Lim H F Lee S H Chotirmall G H Dong J Abisheganaden J A Wedzicha S C Schuster B P Horton J J Y Sung Source Type: research

Understanding PFAS toxicity through cell culture metabolomics: Current applications and future perspectives
Environ Int. 2024 Apr 2;186:108620. doi: 10.1016/j.envint.2024.108620. Online ahead of print.ABSTRACTPer- and polyfluoroalkyl substances (PFAS), ubiquitous environmental contaminants, pose significant challenges to ecosystems and human health. While cell cultures have emerged as new approach methodologies (NAMs) in ecotoxicity research, metabolomics is an emerging technique used to characterize the small-molecule metabolites present in cells and to understand their role in various biological processes. Integration of metabolomics with cell cultures, known as cell culture metabolomics, provides a novel and robust tool to un...
Source: Environment International - April 5, 2024 Category: Environmental Health Authors: Thao V Nguyen Phan Nguyen Trang Anu Kumar Source Type: research

Aromatic amine antioxidants (AAs) and p-phenylenediamines-quinones (PPD-Qs) in e-waste recycling industry park: Occupational exposure and liver X receptors (LXRs) disruption potential
In this study, 115 dust and 42 hand wipe samples collected from an e-waste recycling industrial park in central China were analyzed for 19 AAs and 6 PPD-Qs. Notably, the median concentration of ∑6PPD-Qs (1,110 ng/g and 1,970 ng/m2) was significantly higher (p < 0.05, Mann-Whitney U test) than that of ∑6PPDs (147 ng/g and 34.0 ng/m2) in dust and hand wipes. Among the detected analytes, 4-phenylaminodiphenylamine quinone (DPPD-Q) (median: 781 ng/g) and 1,4-Bis(2-naphthylamino) benzene quinone (DNPD-Q) (median: 156 ng/g), were particularly prominent, which were first detected in the e-waste dismantling area. Occupation...
Source: Environment International - April 5, 2024 Category: Environmental Health Authors: Shaohan Zhang Zhipeng Cheng Yuhao Cao Feixiang He Leicheng Zhao Mujtaba Baqar Hongkai Zhu Tao Zhang Hongwen Sun Source Type: research

Differential impact of diesel exhaust particles on glutamatergic and dopaminergic neurons in Caenorhabditis elegans: A neurodegenerative perspective
Environ Int. 2024 Mar 22;186:108597. doi: 10.1016/j.envint.2024.108597. Online ahead of print.ABSTRACTThe growing body of evidence links exposure to particulate matter pollutants with an increased risk of neurodegenerative diseases. In the present study, we investigated whether diesel exhaust particles can induce neurobehavioral alterations associated with neurodegenerative effects on glutamatergic and dopaminergic neurons in Caenorhabditis elegans (C. elegans). Exposure to DEP at concentrations of 0.167 µg/cm2 and 1.67 µg/cm2 resulted in significant developmental delays and altered locomotion behaviour. These effects we...
Source: Environment International - April 5, 2024 Category: Environmental Health Authors: Nivedita Chatterjee Michael Gonz ález-Durruthy Marta Daniela Costa Ana R Ribeiro V ânia Vilas-Boas Daniela Vilasboas-Campos Patr ícia Maciel Ernesto Alfaro-Moreno Source Type: research