Which biomarkers predict hard-to-heal diabetic foot ulcers? A scoping review
Drug Discov Ther. 2023 Dec 22. doi: 10.5582/ddt.2023.01086. Online ahead of print.ABSTRACTDiabetic foot ulcers (DFUs) often develop into hard-to-heal wounds due to complex factors. Several biomarkers capable of identifying those at risk of delayed wound healing have been reported. Controlling or targeting these biomarkers could prevent the progression of DFUs into hard-to-heal wounds. This scoping review aimed to identify the key biomarkers that can predict hard-to-heal DFUs. Studies that reported biomarkers related to hard-to-heal DFUs, from 1980 to 2023, were mapped. Studies were collected from the following databases: M...
Source: Drug Discoveries and Therapeutics - December 24, 2023 Category: Drugs & Pharmacology Authors: Qi Qin Daijiro Haba Gojiro Nakagami Source Type: research

Single intratracheal administration toxicity study on safety of vapor inhalation of electrolyzed reduced water in rats
This study confirmed the safety of intratracheal ERW infusion and demonstrated the low risk of acute toxicity for inhalation exposure to ERW aerosol or vapor. Therefore, ERW may be an effective air purifier against viruses or bacteria.PMID:38143076 | DOI:10.5582/ddt.2023.01080 (Source: Drug Discoveries and Therapeutics)
Source: Drug Discoveries and Therapeutics - December 24, 2023 Category: Drugs & Pharmacology Authors: Yuko Imanaka Wada Yoshinao Okajima Yutaka Oshima Ken-Ichi Shimokawa Masahiro Okajima Fumiyoshi Ishii Source Type: research

Which biomarkers predict hard-to-heal diabetic foot ulcers? A scoping review
Drug Discov Ther. 2023 Dec 22. doi: 10.5582/ddt.2023.01086. Online ahead of print.ABSTRACTDiabetic foot ulcers (DFUs) often develop into hard-to-heal wounds due to complex factors. Several biomarkers capable of identifying those at risk of delayed wound healing have been reported. Controlling or targeting these biomarkers could prevent the progression of DFUs into hard-to-heal wounds. This scoping review aimed to identify the key biomarkers that can predict hard-to-heal DFUs. Studies that reported biomarkers related to hard-to-heal DFUs, from 1980 to 2023, were mapped. Studies were collected from the following databases: M...
Source: Drug Discoveries and Therapeutics - December 24, 2023 Category: Drugs & Pharmacology Authors: Qi Qin Daijiro Haba Gojiro Nakagami Source Type: research

Single intratracheal administration toxicity study on safety of vapor inhalation of electrolyzed reduced water in rats
This study confirmed the safety of intratracheal ERW infusion and demonstrated the low risk of acute toxicity for inhalation exposure to ERW aerosol or vapor. Therefore, ERW may be an effective air purifier against viruses or bacteria.PMID:38143076 | DOI:10.5582/ddt.2023.01080 (Source: Drug Discoveries and Therapeutics)
Source: Drug Discoveries and Therapeutics - December 24, 2023 Category: Drugs & Pharmacology Authors: Yuko Imanaka Wada Yoshinao Okajima Yutaka Oshima Ken-Ichi Shimokawa Masahiro Okajima Fumiyoshi Ishii Source Type: research

Which biomarkers predict hard-to-heal diabetic foot ulcers? A scoping review
Drug Discov Ther. 2023 Dec 22. doi: 10.5582/ddt.2023.01086. Online ahead of print.ABSTRACTDiabetic foot ulcers (DFUs) often develop into hard-to-heal wounds due to complex factors. Several biomarkers capable of identifying those at risk of delayed wound healing have been reported. Controlling or targeting these biomarkers could prevent the progression of DFUs into hard-to-heal wounds. This scoping review aimed to identify the key biomarkers that can predict hard-to-heal DFUs. Studies that reported biomarkers related to hard-to-heal DFUs, from 1980 to 2023, were mapped. Studies were collected from the following databases: M...
Source: Drug Discoveries and Therapeutics - December 24, 2023 Category: Drugs & Pharmacology Authors: Qi Qin Daijiro Haba Gojiro Nakagami Source Type: research

Single intratracheal administration toxicity study on safety of vapor inhalation of electrolyzed reduced water in rats
This study confirmed the safety of intratracheal ERW infusion and demonstrated the low risk of acute toxicity for inhalation exposure to ERW aerosol or vapor. Therefore, ERW may be an effective air purifier against viruses or bacteria.PMID:38143076 | DOI:10.5582/ddt.2023.01080 (Source: Drug Discoveries and Therapeutics)
Source: Drug Discoveries and Therapeutics - December 24, 2023 Category: Drugs & Pharmacology Authors: Yuko Imanaka Wada Yoshinao Okajima Yutaka Oshima Ken-Ichi Shimokawa Masahiro Okajima Fumiyoshi Ishii Source Type: research

Lack of information on gender differences in the package inserts of prescription drugs in Japan
Drug Discov Ther. 2023 Dec 15. doi: 10.5582/ddt.2023.01093. Online ahead of print.ABSTRACTThe package inserts of prescription drugs provide essential information for the proper administration of pharmacotherapy. The incidence of adverse reactions for several drugs is known to be higher in women than in men. However, no studies have examined whether information on gender differences is included in Japanese package inserts. Therefore, this study investigated information on gender differences in the package inserts of Japanese prescription drugs, using the drug information database JAMES provided by the Medical Information Sy...
Source: Drug Discoveries and Therapeutics - December 17, 2023 Category: Drugs & Pharmacology Authors: Narumi Maida Shingo Kondo Masanori Ogawa Naoko Hayashi Hiroki Iwata Noriko Kobayashi Katsunori Yamaura Source Type: research