Implications of Concurrent Vestibular Dysfunction in Pediatric Hearing Loss
AbstractPurpose of the ReviewIt is known that the prevalence of vestibular impairment in children with sensorineural hearing loss (SNHL) is high and can lead to balance deficits. In this review, we look beyond balance and consider the impact of this multisensory deficit on neurocognitive function and navigation with the aim of explaining some of the variability in outcomes seen in cochlear implant populations, considering how to ameliorate these outcomes with targeted rehabilitative strategies.Recent FindingsCongenital or early acquired vestibular impairment associated with SNHL impacts multiple cognitive domains including...
Source: Current Otorhinolaryngology Reports - June 8, 2020 Category: ENT & OMF Source Type: research

Unilateral Hearing Loss and Single-Sided Deafness in Children: an Update on Diagnosis and Management
AbstractPurpose of ReviewThis review highlights our current understanding of the impact of unilateral hearing loss and single-sided deafness in children, offering insight into diagnosis and management.Recent FindingsChildren with unilateral hearing loss develop an aural preference toward their better hearing ear, leading to difficulties with spatial navigation, balance, speech/language skills, and quality of life when compared with typical hearing peers. Cochlear nerve aplasia and cytomegalovirus are among the most common etiologies for unilateral hearing loss, which has important implications for treatment. Hearing rehabi...
Source: Current Otorhinolaryngology Reports - June 7, 2020 Category: ENT & OMF Source Type: research

Vocal Fold Paresis 2020
AbstractPurpose of ReviewAlthough the clinical significance of vocal fold paresis is generally acknowledged among specialists, details of evaluation and diagnosis remain highly debated.Recent FindingsMany studies evaluating vocal fold paresis have been performed in the last two decades; most are retrospective and fraught with methodological concerns. Diagnosis and management of paresis remain founded primarily on experience and opinion with little high-quality evidence to support clinical practice.SummaryUniversally agreed-upon standards for diagnosis remain elusive. Most laryngologists diagnose paresis by laryngoscopic or...
Source: Current Otorhinolaryngology Reports - June 3, 2020 Category: ENT & OMF Source Type: research

Surgical Considerations for Laryngeal Reinnervation and Future Research Directions
AbstractPurpose of ReviewThis paper examines the history, current use, and future directions of laryngeal reinnervation surgery.Recent FindingsNonselective laryngeal reinnervation has been refined as a surgical technique for use in unilateral vocal fold paralysis.Selective laryngeal reinnervation is a viable surgical option for bilateral vocal fold paralysis. The use of laryngeal pacing devices, nimodipine, stem cells, and manipulation of the cellular and chemical microenvironment are future areas of study for laryngeal reinnervation.SummaryWhile both thyroplasty and injection laryngoplasty are highly effective and remain ...
Source: Current Otorhinolaryngology Reports - June 3, 2020 Category: ENT & OMF Source Type: research

Laryngeal Electromyography: Present and Future
The objective of this review is to present recent advances in LEMG.Recent FindingsThe addition of quantitative analysis and adductor synkinesis testing to the traditional qualitative analysis has improved the accuracy of LEMG and provide opportunities for future research.SummaryEstablishing a team as well as having a standardized testing and reporting protocol will contribute greatly to the clinical value and research utility of LEMG. (Source: Current Otorhinolaryngology Reports)
Source: Current Otorhinolaryngology Reports - June 2, 2020 Category: ENT & OMF Source Type: research

Update on Auditory Neuropathy/Dyssynchrony in Children
This article is meant to update clinicians on best practices for diagnosis and management of AN/AD.Recent FindingsExciting advances in genetics present opportunities for additional evidence to classify AN/AD based on site of lesion, and may lead to additional understanding of the pathophysiology as well as prognosis. Cochlear implantation continues to be a highly effective intervention for managing AN/AD in pediatric patients.SummaryAN/AD can be a challenging condition to manage given the heterogeneity of its presentation and variety of options for management. Ultimately, clinicians must tailor treatment to the individual ...
Source: Current Otorhinolaryngology Reports - June 2, 2020 Category: ENT & OMF Source Type: research

Management of Congenital Cytomegalovirus-Related Hearing Loss
AbstractPurpose of ReviewThe aim of this report is to review the current literature regarding the diagnosis, treatment, management, and rehabilitation of congenital cytomegalovirus (cCMV) –associated sensorineural hearing loss (SNHL).Recent FindingsHearing-targeted CMV screening is successful in identifying cases of cCMV-related hearing loss. However, a significant number of children who develop cCMV-related SNHL may not be detected on newborn hearing screening, and it may be cost-effective to implement a universal CMV screening program. We also broadly review the management and audiologic rehabilitation of cCMV-associat...
Source: Current Otorhinolaryngology Reports - May 28, 2020 Category: ENT & OMF Source Type: research

A Practical Approach to Genetic Testing for Pediatric Hearing Loss
We present the most recent research in the field followed by our recommended diagnostic algorithm incorporating genetic testing. We then provide case examples of commonly encountered patient presentations as further guidance.Recent FindingsGenetic testing has the highest diagnostic yield of any single test in the evaluation of children with congenital bilateral severe-to-profound hearing loss. For unilateral or asymmetric hearing loss, imaging is typically more informative initially than genetic testing. Recent data show that syndromic forms of hearing loss are more common than previously appreciated.SummaryA thorough and ...
Source: Current Otorhinolaryngology Reports - May 25, 2020 Category: ENT & OMF Source Type: research

Classification of Salivary Gland Disorders
AbstractPurpose of ReviewTo offer a fresh perspective on the evolving management of salivary gland disease by introducing a sequence of articles organized by a classification system grouping disorders by etiology.Recent FindingsSialendoscopy has been successful in improving the management of salivary gland disease. This endoscopic approach to imaging and instrumentation of the salivary duct system has been a focal point of recent discussion. The overall management of salivary pain and swelling as well as xerostomia and sialorrhea has improved through additional treatment options including increased application non-surgical...
Source: Current Otorhinolaryngology Reports - May 25, 2020 Category: ENT & OMF Source Type: research

Updates to the Current Understanding of the Relationship Between Allergy and Chronic Sinusitis
AbstractPurpose of ReviewTo examine the relationship of chronic rhinosinusitis (CRS) and atopic disease.Recent FindingsCRS with nasal polyps (CRSwNP) has been shown to be associated with high aeroallergen sensitivity and local allergic response, but with no difference in imaging, symptomatic severity, or disease recurrence rates in atopic vs. non-atopic individuals. There is conflicting evidence for CRS without nasal polyps (CRSsNP) with regard to the relationship with atopic disease. There may, however, be differential molecular profiles between atopic and non-atopic patients with CRSsNP.SummaryThere is no consensus as to...
Source: Current Otorhinolaryngology Reports - April 13, 2020 Category: ENT & OMF Source Type: research

Biologic Therapeutics and Their Role in Allergic Disease of the Unified Airway
AbstractPurpose of ReviewRecent advances have been made in the use of biologic therapies for chronic inflammatory diseases of the unified airway. The purpose of this review is to summarize the current state of knowledge for biologic therapies in chronic airway disease, including indications for use, mechanisms of action, and future needs for research.Recent FindingsThere are currently four classes of FDA-approved biologic therapies for treatment of inflammatory airway diseases: Dupilumab (anti-IL-4R α) is approved for both moderate to severe allergic asthma and chronic rhinosinusitis with nasal polyps, including aspirin-e...
Source: Current Otorhinolaryngology Reports - April 7, 2020 Category: ENT & OMF Source Type: research

Setting up an Office Allergy Practice: Current Recommendations for Sterility and Supervision
AbstractPurpose of ReviewDiscuss optimal conditions for the office delivery of allergy immunotherapy with regard to medical personnel supervision and techniques for sterility of antigen vial preparation and delivery.Recent FindingsThe revised USP 797 pharmaceutical compounding guidelines, combined with allergen extract preparation directions provide clear instructions for the general supervision and oversight of allergen preparation for immunotherapy.SummarySterility of antigen vial preparation and supervision of office personnel delivering and preparing allergy immunotherapy are critical points of competency allowing for ...
Source: Current Otorhinolaryngology Reports - April 2, 2020 Category: ENT & OMF Source Type: research

Sinonasal Squamous Cell Carcinoma: Etiology, Pathogenesis, and the Role of Human Papilloma Virus
AbstractPurpose of ReviewSinonasal squamous cell carcinoma (SNSCC) is a rare disease with considerable histologic diversity. Currently, there is a poor understanding of the etiology and pathogenesis of SNSCC. Here, we review recent literature to summarize what is known regarding (1) the etiology of SNSCC, (2) the role of Human Papilloma Virus (HPV) in SNSCC, and (2) the molecular underpinnings of SNSCC.Recent Findings1. High risk HPV appears to play a role in the pathogenesis of a subset of SNSCCs. SNSCCs with high risk HPV have improved survival compared with those without HPV and occur in patients who are younger, simila...
Source: Current Otorhinolaryngology Reports - March 23, 2020 Category: ENT & OMF Source Type: research

Controversies in Skin Testing for Allergic Rhinitis
This article will review different methods of skin testing available for allergic rhinitis, emphasizing controversies and challenges associated with these techniques.Recent FindingsThe utility of quantitative skin testing has been debated in current literature, as has the accuracy of skin versus in vitro testing. Single- and pauci-allergen immunotherapy (AIT) have also shown good outcomes, thus questioning the use of large testing panels. Recent studies further support the use of standardized and recombinant antigens.SummarySkin testing remains a safe and dependable tool in the diagnosis and management of allergic rhinitis...
Source: Current Otorhinolaryngology Reports - March 22, 2020 Category: ENT & OMF Source Type: research

Perioperative Considerations in Endoscopic Skull Base Surgery
AbstractPurpose of the ReviewPresent an overview of perioperative considerations specific to endoscopic skull base surgery necessary to maximize successful outcomes.Recent FindingsThe majority of perioperative considerations for endoscopic skull base surgery lack strong supporting evidence and frequently have varied use or implementation amongst institutions. A notable exception comes from a recent randomized controlled trial demonstrating the benefit of lumbar drainage in high-risk cerebrospinal fluid leaks.SummarySkull base surgeons must consider a multitude of perioperative factors. While many components of perioperativ...
Source: Current Otorhinolaryngology Reports - March 18, 2020 Category: ENT & OMF Source Type: research