Revision Stapes Surgery
AbstractPurpose of ReviewThis review briefly covers the history of stapedectomy, discusses the indications and problems encountered with revision surgery, and provides case examples with solutions.Recent FindingsRevision surgery is challenging and successful outcome even in the most experienced specialists is 45 –71%, which is far less than that of primary surgery.SummaryCareful evaluation of the reasons for reoperation, anticipation of the common problems, and patient education on reasonable expectations are all very important for success. (Source: Current Otorhinolaryngology Reports)
Source: Current Otorhinolaryngology Reports - January 24, 2022 Category: ENT & OMF Source Type: research

The Nasal Vestibular Body and Its Role in Nasal Obstruction
AbstractPurpose of ReviewThe nasal vestibular body (NVB) is a recently reported, dynamic swell body present in the anterior nasal airway that may contribute to symptomatic nasal airway obstruction. This review aims to summarize what is currently known regarding the diagnosis and management of this newly identified, and readily treated, structure.Recent FindingsNVB can be a prominent finding in nasal airway pathway; its role as a component of nasal obstruction can be assessed by chemical decongestion of the NVB soft tissue alone. NVB soft tissue reduction can be surgically achieved using radiofrequency ablation. This modali...
Source: Current Otorhinolaryngology Reports - January 22, 2022 Category: ENT & OMF Source Type: research

Prosthesis Selection in Stapes Surgery
AbstractPurpose of the reviewThis review was undertaken to examine factors that enhance successful stapes surgery and minimize complications as they relate to prosthesis selection. By exploring the evolution of the current stapes prostheses with respect to biomaterials, mechanical and intra-operative considerations, the surgeon should be able to better determine which prosthesis is appropriate for his or her patient.Recent findingsCurrent stapes prostheses can be divided into those that require manual crimping and those that don ’t. Although the heat-activated nitinol prostheses circumvent the need for crimping, some of ...
Source: Current Otorhinolaryngology Reports - January 21, 2022 Category: ENT & OMF Source Type: research

Epidemiology and Prevention of HPV-Associated Squamous Cell Carcinoma
AbstractPurpose of ReviewThis review aims to provide an up-to-date overview of epidemiology and prevention in HPV-associated cancer focused in oropharyngeal cancer (OPC).Recent Findings:Current epidemiologic trends suggest that HPV-positive OPC remains a male epidemic; however, latest changes demonstrate an increase in incidence of the older population.Oral HPV infection precedes incidence of OPC; however, the time after infection at which carcinogenesis begins is still unknown. Persistent infection may lead to OPC.HPV vaccination decreases oral HPV prevalence. In addition, OPC was recently added as an indication for this ...
Source: Current Otorhinolaryngology Reports - January 20, 2022 Category: ENT & OMF Source Type: research

Risk Stratification of HPV-Associated Oropharyngeal Squamous Cell Carcinoma: Are All Tumors Created Equally?
AbstractPurpose of ReviewWe summarize recent knowledge on risk stratification of HPV-associated (HPV) oropharyngeal carcinoma (OPC).Recent FindingsThe 8th edition TNM (TNM-8) depicts prognosis using anatomic disease extent. However, heterogeneity exists, especially within stage I disease. Radiologic extranodal extension is a strong prognostic factor and has the potential to refine TNM-8 cN classification. Smoking modifies mortality risk, but underlying mechanisms and optimal smoking metrics for risk stratification remain unclear. HPV genotyping may affect prognosis where HPV-16 carries better prognosis vs. other HPV subtyp...
Source: Current Otorhinolaryngology Reports - January 8, 2022 Category: ENT & OMF Source Type: research

Cochlear Implantation in Advanced Otosclerosis: Pitfalls and Successes
AbstractPurpose of ReviewThis review will highlight recent outcome-based evidence guiding decision making for cochlear implantation in advanced otosclerosis, related complications, and technical surgical considerations in otosclerosis and the obstructed cochlea.Recent FindingsCochlear implantation in advanced otosclerosis results in consistent, excellent auditory outcomes with improvement in both objective speech recognition scores and subjective quality of life measures. Facial nerve stimulation may occur at higher rates in otosclerosis cochlear implant recipients. Cochlear implantation in the setting of luminal obstructi...
Source: Current Otorhinolaryngology Reports - January 7, 2022 Category: ENT & OMF Source Type: research

Endoscopic and Robotic Stapes Surgery: Review with Emphasis on Recent Surgical Refinements
This article reviews the use of endoscopes and robotical assistance for stapes surgery.Recent FindingsWhile different robotic models have been developed, 2 models for stapes surgery have been used in the clinical setting. These can be used concomitant to an endoscope or microscope. Endoscopes are used on a regular base regarding stapes surgery with similar outcomes as microscopes. Endoscopic stapes surgery shows similar audiological results to microscopic technique with an advantage of less postoperative dysgeusia and pain. Its utility in cases of revision surgery or malformation is emphasized.SummaryEndoscopic stapes surg...
Source: Current Otorhinolaryngology Reports - January 6, 2022 Category: ENT & OMF Source Type: research

Immune Landscape and Role of Immunotherapy in Treatment of HPV-Associated Head and Neck Squamous Cell Carcinoma (HNSCC)
AbstractPurpose of ReviewTo review and summarize recent findings on the immune system constituents relevant to the development, proliferation, and treatment of human papillomavirus (HPV)-associated head and neck squamous cell carcinoma (HNSCC), focusing on experimental therapies currently in testing or development.Recent FindingsHPV-associated HNSCC exhibits an inflamed phenotype targeted at HPV-specific antigens that may contribute to improved survival over HPV-negative HNSCC. Combinations of immunotherapy such as immune checkpoint inhibition and therapeutic vaccination take advantage of the underlying potential for T cel...
Source: Current Otorhinolaryngology Reports - January 5, 2022 Category: ENT & OMF Source Type: research

Role of Radiologic Imaging in Otosclerosis
AbstractPurpose of ReviewTo review the role of imaging in otosclerosis with an emphasis on pre- and post-operative imaging evaluation.Recent FindingsPre-operative CT imaging can help define the extent of bone involvement in otosclerosis and may help avoid surgical complications due to variant anatomy or unsuspected alternative causes of conductive hearing loss. In patients with recurrent hearing loss after surgery, CT imaging can clarify prosthesis position and re-assess anatomy.SummaryCT imaging complements otologic exam and audiometry findings in patients with suspected otosclerosis, for pre-operative planning, and post-...
Source: Current Otorhinolaryngology Reports - January 4, 2022 Category: ENT & OMF Source Type: research

Biomarker-Based Evaluation of Treatment Response and Surveillance of HPV-Associated Squamous Cell Carcinoma
AbstractPurpose of ReviewTo summarize and critically review recent literature concerning plasma and oral rinse biomarker-based evaluation of treatment response and disease surveillance for HPV-associated head and neck squamous cell carcinoma.Recent FindingsQuantification of HPV in plasma and oral rinse samples holds promise for predicting response to treatment and surveying for disease recurrence. Detection of mutations and epigenetic changes in circulating tumor DNA may be similarly impactful for both HPV-associated and non-HPV-associated head and neck squamous cell carcinomas (HNSCC).SummaryQuantification of HPV DNA copy...
Source: Current Otorhinolaryngology Reports - January 4, 2022 Category: ENT & OMF Source Type: research

Understanding the Cost-Effectiveness of Hearing Aids and Surgery for the Treatment of Otosclerosis
AbstractPurpose of ReviewTo summarize and critically review recent literature on the relative cost-effectiveness of hearing augmentation versus stapes surgery for the treatment of otosclerosis.Recent FindingsOtosclerosis leads to reduced patient quality of life, which can be ameliorated by either stapes surgery, or hearing aid usage. The success of stapes surgery is high, and the risks of serious postoperative complications are low. Hearing aids don ’t have the complications of surgery but are associated with long-term costs. Cost-effectiveness models have shown that stapes surgery is a cost-effective method for treating...
Source: Current Otorhinolaryngology Reports - January 4, 2022 Category: ENT & OMF Source Type: research

Brow Lifting and Upper Facial Esthetics: Current Techniques and Considerations
AbstractPurpose of ReviewTo review contemporary considerations regarding upper facial esthetics and modern brow lifting techniques, including their selection criteria and efficacy.Recent FindingsMitek suture anchor and K-wire fixation were found to be viable endoscopic fixation techniques with various advantages over other methods. There has been a significant focus on developing minimally invasive lateral brow lifts. These often vary in degrees of lift and durability, with techniques such as browpexy/transblepharoplasty lifts having questionable efficacy, to subcutaneous temporal and combination lifts which appear to prod...
Source: Current Otorhinolaryngology Reports - November 24, 2021 Category: ENT & OMF Source Type: research

Neonatal Nasal Obstruction
AbstractPurpose of ReviewNeonates are obligate nasal breathers. As a result, they are uniquely suspectable to nasal obstruction, particularly when bilateral, and can present with life-threatening respiratory distress, feeding concerns, or noisy breathing. The differential diagnosis for pediatric nasal obstruction is broad; nasal obstruction in the post-natal period can manifest in different levels of the nasal passageway and vary in laterality and severity.Recent FindingClinicians must be able to quickly identify signs and symptoms, develop an appropriate differential diagnosis, and plan treatment to manage neonatal nasal ...
Source: Current Otorhinolaryngology Reports - November 12, 2021 Category: ENT & OMF Source Type: research

Advances in Hair Restoration
AbstractPurpose of ReviewTreatment for alopecia remains limited in terms of medication side effect profile, patient adherence to treatment, and clinical response. We sought to review the literature for burgeoning therapies affecting hair growth through regulation of paracrine signaling and its effect on dermal papilla cells.Recent FindingsNewly proposed treatments for alopecia, including stem cell therapy derived from adipose tissue, hair follicles, umbilical cord blood, or bone marrow, and extracellular vesicles, such as exosomes, are tied to hair follicle regulation and regeneration through paracrine factor signaling, sp...
Source: Current Otorhinolaryngology Reports - November 12, 2021 Category: ENT & OMF Source Type: research

Analysis and Assessment of Facial Aging
AbstractPurpose of ReviewThe goal of this review is to highlight the important clinical considerations that impact the facial aging process and discuss current assessment tools that are available to help guide the clinician on appropriate facial rejuvenation modalities.Recent FindingsExtrinsic and intrinsic factors and their effects on facial aging continue to be studied. Ethnic and racial backgrounds play a critical role in the facial aging process. Gender ’s impact on facial aging is explored. Several assessment tools have been developed to examine various subunits of the face, and other assessments have been created t...
Source: Current Otorhinolaryngology Reports - November 12, 2021 Category: ENT & OMF Source Type: research