The Integration of Top-down and Bottom-up Inputs to the Striatal Cholinergic Interneurons
CONCLUSION: This study provides in vivo evidence that the multiphasic ChI response may require both top-down and bottom-up inputs. The findings suggest that the firing pattern of ChIs correlated to the iLFP might be a useful tool for estimating the degree of contribution of top-down and bottom-up inputs in regulating the firing activity of ChIs.PMID:38420787 | DOI:10.2174/1570159X22666231115151403 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - February 29, 2024 Category: Drugs & Pharmacology Authors: Yan-Feng Zhang John N J Reynolds Source Type: research

The Integration of Top-down and Bottom-up Inputs to the Striatal Cholinergic Interneurons
CONCLUSION: This study provides in vivo evidence that the multiphasic ChI response may require both top-down and bottom-up inputs. The findings suggest that the firing pattern of ChIs correlated to the iLFP might be a useful tool for estimating the degree of contribution of top-down and bottom-up inputs in regulating the firing activity of ChIs.PMID:38420787 | DOI:10.2174/1570159X22666231115151403 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - February 29, 2024 Category: Drugs & Pharmacology Authors: Yan-Feng Zhang John N J Reynolds Source Type: research

The Integration of Top-down and Bottom-up Inputs to the Striatal Cholinergic Interneurons
CONCLUSION: This study provides in vivo evidence that the multiphasic ChI response may require both top-down and bottom-up inputs. The findings suggest that the firing pattern of ChIs correlated to the iLFP might be a useful tool for estimating the degree of contribution of top-down and bottom-up inputs in regulating the firing activity of ChIs.PMID:38420787 | DOI:10.2174/1570159X22666231115151403 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - February 29, 2024 Category: Drugs & Pharmacology Authors: Yan-Feng Zhang John N J Reynolds Source Type: research

The Integration of Top-down and Bottom-up Inputs to the Striatal Cholinergic Interneurons
CONCLUSION: This study provides in vivo evidence that the multiphasic ChI response may require both top-down and bottom-up inputs. The findings suggest that the firing pattern of ChIs correlated to the iLFP might be a useful tool for estimating the degree of contribution of top-down and bottom-up inputs in regulating the firing activity of ChIs.PMID:38420787 | DOI:10.2174/1570159X22666231115151403 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - February 29, 2024 Category: Drugs & Pharmacology Authors: Yan-Feng Zhang John N J Reynolds Source Type: research

The Integration of Top-down and Bottom-up Inputs to the Striatal Cholinergic Interneurons
CONCLUSION: This study provides in vivo evidence that the multiphasic ChI response may require both top-down and bottom-up inputs. The findings suggest that the firing pattern of ChIs correlated to the iLFP might be a useful tool for estimating the degree of contribution of top-down and bottom-up inputs in regulating the firing activity of ChIs.PMID:38420787 | DOI:10.2174/1570159X22666231115151403 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - February 29, 2024 Category: Drugs & Pharmacology Authors: Yan-Feng Zhang John N J Reynolds Source Type: research

The Integration of Top-down and Bottom-up Inputs to the Striatal Cholinergic Interneurons
CONCLUSION: This study provides in vivo evidence that the multiphasic ChI response may require both top-down and bottom-up inputs. The findings suggest that the firing pattern of ChIs correlated to the iLFP might be a useful tool for estimating the degree of contribution of top-down and bottom-up inputs in regulating the firing activity of ChIs.PMID:38420787 | DOI:10.2174/1570159X22666231115151403 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - February 29, 2024 Category: Drugs & Pharmacology Authors: Yan-Feng Zhang John N J Reynolds Source Type: research

The Integration of Top-down and Bottom-up Inputs to the Striatal Cholinergic Interneurons
CONCLUSION: This study provides in vivo evidence that the multiphasic ChI response may require both top-down and bottom-up inputs. The findings suggest that the firing pattern of ChIs correlated to the iLFP might be a useful tool for estimating the degree of contribution of top-down and bottom-up inputs in regulating the firing activity of ChIs.PMID:38420787 | DOI:10.2174/1570159X22666231115151403 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - February 29, 2024 Category: Drugs & Pharmacology Authors: Yan-Feng Zhang John N J Reynolds Source Type: research

The Integration of Top-down and Bottom-up Inputs to the Striatal Cholinergic Interneurons
CONCLUSION: This study provides in vivo evidence that the multiphasic ChI response may require both top-down and bottom-up inputs. The findings suggest that the firing pattern of ChIs correlated to the iLFP might be a useful tool for estimating the degree of contribution of top-down and bottom-up inputs in regulating the firing activity of ChIs.PMID:38420787 | DOI:10.2174/1570159X22666231115151403 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - February 29, 2024 Category: Drugs & Pharmacology Authors: Yan-Feng Zhang John N J Reynolds Source Type: research

The Integration of Top-down and Bottom-up Inputs to the Striatal Cholinergic Interneurons
CONCLUSION: This study provides in vivo evidence that the multiphasic ChI response may require both top-down and bottom-up inputs. The findings suggest that the firing pattern of ChIs correlated to the iLFP might be a useful tool for estimating the degree of contribution of top-down and bottom-up inputs in regulating the firing activity of ChIs.PMID:38420787 | DOI:10.2174/1570159X22666231115151403 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - February 29, 2024 Category: Drugs & Pharmacology Authors: Yan-Feng Zhang John N J Reynolds Source Type: research

Protective Role of Electroacupuncture Against Cognitive Impairment in Neurological Diseases
Curr Neuropharmacol. 2024 Feb 12. doi: 10.2174/1570159X22999240209102116. Online ahead of print.ABSTRACTMany neurological diseases can lead to cognitive impairment in patients, which includes dementia and mild cognitive impairment and thus create a heavy burden both to their families and public health. Due to the limited effectiveness of medications in treating cognitive impairment, it is imperative to develop alternative treatments. Electroacupuncture (EA), a required method for Traditional Chinese Medicine, has the potential treatment of cognitive impairment. However, the molecular mechanisms involved have not been fully...
Source: Current Neuropharmacology - February 21, 2024 Category: Drugs & Pharmacology Authors: Yueyang Xin Siqi Zhou Tiantian Chu Yaqun Zhou Aijun Xu Source Type: research

Protective Role of Electroacupuncture Against Cognitive Impairment in Neurological Diseases
Curr Neuropharmacol. 2024 Feb 12. doi: 10.2174/1570159X22999240209102116. Online ahead of print.ABSTRACTMany neurological diseases can lead to cognitive impairment in patients, which includes dementia and mild cognitive impairment and thus create a heavy burden both to their families and public health. Due to the limited effectiveness of medications in treating cognitive impairment, it is imperative to develop alternative treatments. Electroacupuncture (EA), a required method for Traditional Chinese Medicine, has the potential treatment of cognitive impairment. However, the molecular mechanisms involved have not been fully...
Source: Current Neuropharmacology - February 21, 2024 Category: Drugs & Pharmacology Authors: Yueyang Xin Siqi Zhou Tiantian Chu Yaqun Zhou Aijun Xu Source Type: research

Protective Role of Electroacupuncture Against Cognitive Impairment in Neurological Diseases
Curr Neuropharmacol. 2024 Feb 12. doi: 10.2174/1570159X22999240209102116. Online ahead of print.ABSTRACTMany neurological diseases can lead to cognitive impairment in patients, which includes dementia and mild cognitive impairment and thus create a heavy burden both to their families and public health. Due to the limited effectiveness of medications in treating cognitive impairment, it is imperative to develop alternative treatments. Electroacupuncture (EA), a required method for Traditional Chinese Medicine, has the potential treatment of cognitive impairment. However, the molecular mechanisms involved have not been fully...
Source: Current Neuropharmacology - February 21, 2024 Category: Drugs & Pharmacology Authors: Yueyang Xin Siqi Zhou Tiantian Chu Yaqun Zhou Aijun Xu Source Type: research

Protective Role of Electroacupuncture Against Cognitive Impairment in Neurological Diseases
Curr Neuropharmacol. 2024 Feb 12. doi: 10.2174/1570159X22999240209102116. Online ahead of print.ABSTRACTMany neurological diseases can lead to cognitive impairment in patients, which includes dementia and mild cognitive impairment and thus create a heavy burden both to their families and public health. Due to the limited effectiveness of medications in treating cognitive impairment, it is imperative to develop alternative treatments. Electroacupuncture (EA), a required method for Traditional Chinese Medicine, has the potential treatment of cognitive impairment. However, the molecular mechanisms involved have not been fully...
Source: Current Neuropharmacology - February 21, 2024 Category: Drugs & Pharmacology Authors: Yueyang Xin Siqi Zhou Tiantian Chu Yaqun Zhou Aijun Xu Source Type: research

Protective Role of Electroacupuncture Against Cognitive Impairment in Neurological Diseases
Curr Neuropharmacol. 2024 Feb 12. doi: 10.2174/1570159X22999240209102116. Online ahead of print.ABSTRACTMany neurological diseases can lead to cognitive impairment in patients, which includes dementia and mild cognitive impairment and thus create a heavy burden both to their families and public health. Due to the limited effectiveness of medications in treating cognitive impairment, it is imperative to develop alternative treatments. Electroacupuncture (EA), a required method for Traditional Chinese Medicine, has the potential treatment of cognitive impairment. However, the molecular mechanisms involved have not been fully...
Source: Current Neuropharmacology - February 21, 2024 Category: Drugs & Pharmacology Authors: Yueyang Xin Siqi Zhou Tiantian Chu Yaqun Zhou Aijun Xu Source Type: research

Protective Role of Electroacupuncture Against Cognitive Impairment in Neurological Diseases
Curr Neuropharmacol. 2024 Feb 12. doi: 10.2174/1570159X22999240209102116. Online ahead of print.ABSTRACTMany neurological diseases can lead to cognitive impairment in patients, which includes dementia and mild cognitive impairment and thus create a heavy burden both to their families and public health. Due to the limited effectiveness of medications in treating cognitive impairment, it is imperative to develop alternative treatments. Electroacupuncture (EA), a required method for Traditional Chinese Medicine, has the potential treatment of cognitive impairment. However, the molecular mechanisms involved have not been fully...
Source: Current Neuropharmacology - February 21, 2024 Category: Drugs & Pharmacology Authors: Yueyang Xin Siqi Zhou Tiantian Chu Yaqun Zhou Aijun Xu Source Type: research