Insights Into the Role of Copper in Neurodegenerative Diseases and the Therapeutic Potential of Natural Compounds
Curr Neuropharmacol. 2023 Nov 15. doi: 10.2174/1570159X22666231103085859. Online ahead of print.ABSTRACTNeurodegenerative diseases encompass a collection of neurological disorders originating from the progressive degeneration of neurons, resulting in the dysfunction of neurons. Unfortunately, effective therapeutic interventions for these diseases are presently lacking. Copper (Cu), a crucial trace element within the human body, assumes a pivotal role in various biological metabolic processes, including energy metabolism, antioxidant defense, and neurotransmission. These processes are vital for the sustenance, growth, and d...
Source: Current Neuropharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: Guangcheng Zhong Xinyue Wang Jiaqi Li Zhouyuan Xie Qiqing Wu Jiaxin Chen Yiyun Wang Ziying Chen Xinyue Cao Tianyao Li Jinman Liu Qi Wang Source Type: research
Insights Into the Role of Copper in Neurodegenerative Diseases and the Therapeutic Potential of Natural Compounds
Curr Neuropharmacol. 2023 Nov 15. doi: 10.2174/1570159X22666231103085859. Online ahead of print.ABSTRACTNeurodegenerative diseases encompass a collection of neurological disorders originating from the progressive degeneration of neurons, resulting in the dysfunction of neurons. Unfortunately, effective therapeutic interventions for these diseases are presently lacking. Copper (Cu), a crucial trace element within the human body, assumes a pivotal role in various biological metabolic processes, including energy metabolism, antioxidant defense, and neurotransmission. These processes are vital for the sustenance, growth, and d...
Source: Current Neuropharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: Guangcheng Zhong Xinyue Wang Jiaqi Li Zhouyuan Xie Qiqing Wu Jiaxin Chen Yiyun Wang Ziying Chen Xinyue Cao Tianyao Li Jinman Liu Qi Wang Source Type: research
Insights Into the Role of Copper in Neurodegenerative Diseases and the Therapeutic Potential of Natural Compounds
Curr Neuropharmacol. 2023 Nov 15. doi: 10.2174/1570159X22666231103085859. Online ahead of print.ABSTRACTNeurodegenerative diseases encompass a collection of neurological disorders originating from the progressive degeneration of neurons, resulting in the dysfunction of neurons. Unfortunately, effective therapeutic interventions for these diseases are presently lacking. Copper (Cu), a crucial trace element within the human body, assumes a pivotal role in various biological metabolic processes, including energy metabolism, antioxidant defense, and neurotransmission. These processes are vital for the sustenance, growth, and d...
Source: Current Neuropharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: Guangcheng Zhong Xinyue Wang Jiaqi Li Zhouyuan Xie Qiqing Wu Jiaxin Chen Yiyun Wang Ziying Chen Xinyue Cao Tianyao Li Jinman Liu Qi Wang Source Type: research
Insights Into the Role of Copper in Neurodegenerative Diseases and the Therapeutic Potential of Natural Compounds
Curr Neuropharmacol. 2023 Nov 15. doi: 10.2174/1570159X22666231103085859. Online ahead of print.ABSTRACTNeurodegenerative diseases encompass a collection of neurological disorders originating from the progressive degeneration of neurons, resulting in the dysfunction of neurons. Unfortunately, effective therapeutic interventions for these diseases are presently lacking. Copper (Cu), a crucial trace element within the human body, assumes a pivotal role in various biological metabolic processes, including energy metabolism, antioxidant defense, and neurotransmission. These processes are vital for the sustenance, growth, and d...
Source: Current Neuropharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: Guangcheng Zhong Xinyue Wang Jiaqi Li Zhouyuan Xie Qiqing Wu Jiaxin Chen Yiyun Wang Ziying Chen Xinyue Cao Tianyao Li Jinman Liu Qi Wang Source Type: research
Insights Into the Role of Copper in Neurodegenerative Diseases and the Therapeutic Potential of Natural Compounds
Curr Neuropharmacol. 2023 Nov 15. doi: 10.2174/1570159X22666231103085859. Online ahead of print.ABSTRACTNeurodegenerative diseases encompass a collection of neurological disorders originating from the progressive degeneration of neurons, resulting in the dysfunction of neurons. Unfortunately, effective therapeutic interventions for these diseases are presently lacking. Copper (Cu), a crucial trace element within the human body, assumes a pivotal role in various biological metabolic processes, including energy metabolism, antioxidant defense, and neurotransmission. These processes are vital for the sustenance, growth, and d...
Source: Current Neuropharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: Guangcheng Zhong Xinyue Wang Jiaqi Li Zhouyuan Xie Qiqing Wu Jiaxin Chen Yiyun Wang Ziying Chen Xinyue Cao Tianyao Li Jinman Liu Qi Wang Source Type: research
Insights Into the Role of Copper in Neurodegenerative Diseases and the Therapeutic Potential of Natural Compounds
Curr Neuropharmacol. 2023 Nov 15. doi: 10.2174/1570159X22666231103085859. Online ahead of print.ABSTRACTNeurodegenerative diseases encompass a collection of neurological disorders originating from the progressive degeneration of neurons, resulting in the dysfunction of neurons. Unfortunately, effective therapeutic interventions for these diseases are presently lacking. Copper (Cu), a crucial trace element within the human body, assumes a pivotal role in various biological metabolic processes, including energy metabolism, antioxidant defense, and neurotransmission. These processes are vital for the sustenance, growth, and d...
Source: Current Neuropharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: Guangcheng Zhong Xinyue Wang Jiaqi Li Zhouyuan Xie Qiqing Wu Jiaxin Chen Yiyun Wang Ziying Chen Xinyue Cao Tianyao Li Jinman Liu Qi Wang Source Type: research
Immunomodulatory Effects of Clozapine: More Than Just a Side Effect in Schizophrenia
Curr Neuropharmacol. 2023 Nov 28. doi: 10.2174/1570159X22666231128101725. Online ahead of print.ABSTRACTRecent evidence suggests a possible relationship between the immune system and schizophrenia spectrum disorders (SSDs), as neuroinflammation appears to play a role in major psychiatric conditions. Neuroinflammation is as a broad concept representing a physiological protective response to infection or injury, but in some cases, especially if chronic, it may represent an expression of maladaptive processes, potentially driving to clinical dysfunction and neurodegeneration. Several studies are concurrently highlighting the ...
Source: Current Neuropharmacology - November 30, 2023 Category: Drugs & Pharmacology Authors: Andrea Amerio Luca Magnani Gabriele Arduino Fabio Fesce Renato de Filippis Alberto Parise Alessandra Costanza Khoa D Nguyen Daniele Saverino Domenico De Berardis Andrea Aguglia Andrea Escelsio Gianluca Serafi Pasquale De Fazio Mario Amore Source Type: research
Immunomodulatory Effects of Clozapine: More Than Just a Side Effect in Schizophrenia
Curr Neuropharmacol. 2023 Nov 28. doi: 10.2174/1570159X22666231128101725. Online ahead of print.ABSTRACTRecent evidence suggests a possible relationship between the immune system and schizophrenia spectrum disorders (SSDs), as neuroinflammation appears to play a role in major psychiatric conditions. Neuroinflammation is as a broad concept representing a physiological protective response to infection or injury, but in some cases, especially if chronic, it may represent an expression of maladaptive processes, potentially driving to clinical dysfunction and neurodegeneration. Several studies are concurrently highlighting the ...
Source: Current Neuropharmacology - November 30, 2023 Category: Drugs & Pharmacology Authors: Andrea Amerio Luca Magnani Gabriele Arduino Fabio Fesce Renato de Filippis Alberto Parise Alessandra Costanza Khoa D Nguyen Daniele Saverino Domenico De Berardis Andrea Aguglia Andrea Escelsio Gianluca Serafi Pasquale De Fazio Mario Amore Source Type: research
Preface
Curr Neuropharmacol. 2024;22(1):1-2. doi: 10.2174/1570159X2201230921145316.NO ABSTRACTPMID:37990610 | DOI:10.2174/1570159X2201230921145316 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - November 22, 2023 Category: Drugs & Pharmacology Authors: Ferdinando Nicoletti Source Type: research
Preface
Curr Neuropharmacol. 2024;22(1):1-2. doi: 10.2174/1570159X2201230921145316.NO ABSTRACTPMID:37990610 | DOI:10.2174/1570159X2201230921145316 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - November 22, 2023 Category: Drugs & Pharmacology Authors: Ferdinando Nicoletti Source Type: research
Preface
Curr Neuropharmacol. 2024;22(1):1-2. doi: 10.2174/1570159X2201230921145316.NO ABSTRACTPMID:37990610 | DOI:10.2174/1570159X2201230921145316 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - November 22, 2023 Category: Drugs & Pharmacology Authors: Ferdinando Nicoletti Source Type: research
Preface
Curr Neuropharmacol. 2024;22(1):1-2. doi: 10.2174/1570159X2201230921145316.NO ABSTRACTPMID:37990610 | DOI:10.2174/1570159X2201230921145316 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - November 22, 2023 Category: Drugs & Pharmacology Authors: Ferdinando Nicoletti Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
