Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain
Curr Neuropharmacol. 2023 Oct 25. doi: 10.2174/1570159X22999231024140544. Online ahead of print.ABSTRACTHumans have long been combating chronic pain. In clinical practice, opioids are first- choice analgesics, but long-term use of these drugs can lead to serious adverse reactions. Finding new, safe and effective pain relievers that are useful treatments for chronic pain is an urgent medical need. Based on accumulating evidence from numerous studies, excess reactive oxygen species (ROS) contribute to the development and maintenance of chronic pain. Some antioxidants are potentially beneficial analgesics in the clinic, but R...
Source: Current Neuropharmacology - November 3, 2023 Category: Drugs & Pharmacology Authors: Peng-Fei Cheng None Yuan-He Meng-Meng Ge Da-Wei Ye Jian-Ping Chen Jin-Xi Wang Source Type: research
Inflammation, Autoimmunity and Neurodegenerative Diseases, Therapeutics and Beyond
Curr Neuropharmacol. 2023 Oct 17. doi: 10.2174/1570159X22666231017141636. Online ahead of print.ABSTRACTNeurodegenerative disease (ND) incidence has recently increased due to improved life expectancy. Alzheimer's (AD) or Parkinson's disease (PD) are the most prevalent NDs. Both diseases are poly genetic, multifactorial and heterogenous. Preventive medicine, a healthy diet, exercise, and controlling comorbidities may delay the onset. After the diseases are diagnosed, therapy is needed to slow progression. Recent studies show that local, peripheral and age-related inflammation accelerates NDs' onset and progression. Patients...
Source: Current Neuropharmacology - October 29, 2023 Category: Drugs & Pharmacology Authors: Jenny Valentina Garmendia Claudia Valentina De Sanctis Viswanath Das Narendran Annadurai Mari án Hajduch Juan Bautista De Sanctis Source Type: research
Inflammation, Autoimmunity and Neurodegenerative Diseases, Therapeutics and Beyond
Curr Neuropharmacol. 2023 Oct 17. doi: 10.2174/1570159X22666231017141636. Online ahead of print.ABSTRACTNeurodegenerative disease (ND) incidence has recently increased due to improved life expectancy. Alzheimer's (AD) or Parkinson's disease (PD) are the most prevalent NDs. Both diseases are poly genetic, multifactorial and heterogenous. Preventive medicine, a healthy diet, exercise, and controlling comorbidities may delay the onset. After the diseases are diagnosed, therapy is needed to slow progression. Recent studies show that local, peripheral and age-related inflammation accelerates NDs' onset and progression. Patients...
Source: Current Neuropharmacology - October 29, 2023 Category: Drugs & Pharmacology Authors: Jenny Valentina Garmendia Claudia Valentina De Sanctis Viswanath Das Narendran Annadurai Mari án Hajduch Juan Bautista De Sanctis Source Type: research
Inflammation, Autoimmunity and Neurodegenerative Diseases, Therapeutics and Beyond
Curr Neuropharmacol. 2023 Oct 17. doi: 10.2174/1570159X22666231017141636. Online ahead of print.ABSTRACTNeurodegenerative disease (ND) incidence has recently increased due to improved life expectancy. Alzheimer's (AD) or Parkinson's disease (PD) are the most prevalent NDs. Both diseases are poly genetic, multifactorial and heterogenous. Preventive medicine, a healthy diet, exercise, and controlling comorbidities may delay the onset. After the diseases are diagnosed, therapy is needed to slow progression. Recent studies show that local, peripheral and age-related inflammation accelerates NDs' onset and progression. Patients...
Source: Current Neuropharmacology - October 29, 2023 Category: Drugs & Pharmacology Authors: Jenny Valentina Garmendia Claudia Valentina De Sanctis Viswanath Das Narendran Annadurai Mari án Hajduch Juan Bautista De Sanctis Source Type: research
Inflammation, Autoimmunity and Neurodegenerative Diseases, Therapeutics and Beyond
Curr Neuropharmacol. 2023 Oct 17. doi: 10.2174/1570159X22666231017141636. Online ahead of print.ABSTRACTNeurodegenerative disease (ND) incidence has recently increased due to improved life expectancy. Alzheimer's (AD) or Parkinson's disease (PD) are the most prevalent NDs. Both diseases are poly genetic, multifactorial and heterogenous. Preventive medicine, a healthy diet, exercise, and controlling comorbidities may delay the onset. After the diseases are diagnosed, therapy is needed to slow progression. Recent studies show that local, peripheral and age-related inflammation accelerates NDs' onset and progression. Patients...
Source: Current Neuropharmacology - October 29, 2023 Category: Drugs & Pharmacology Authors: Jenny Valentina Garmendia Claudia Valentina De Sanctis Viswanath Das Narendran Annadurai Mari án Hajduch Juan Bautista De Sanctis Source Type: research
