Transfersomes: Recent Advances, Mechanisms, Exhaustive Applications, Clinical Trials, and Patents
Curr Drug Deliv. 2024 Feb 21. doi: 10.2174/0115672018295038240209055444. Online ahead of print.ABSTRACTA feasible nano transdermal delivery system generally intends to have specific ideal and distinct characteristics primarily for safety, clinical efficacy, and boosted therapeutic index. The delivery of drugs, particularly macromolecules, across the skin is one of the most strenuous obstacles in front of pharmaceutical scientists. Technology advancement has provided some opportunities to overcome this difficulty by utilising microneedle arrays, ablation, laser methods etc. However, associated uneasiness, painful sensation,...
Source: Current Drug Delivery - February 22, 2024 Category: Drugs & Pharmacology Authors: Deeksha Manchanda Manish Makhija Parijat Pandey Manu Sharma Source Type: research
Transfersomes: Recent Advances, Mechanisms, Exhaustive Applications, Clinical Trials, and Patents
Curr Drug Deliv. 2024 Feb 21. doi: 10.2174/0115672018295038240209055444. Online ahead of print.ABSTRACTA feasible nano transdermal delivery system generally intends to have specific ideal and distinct characteristics primarily for safety, clinical efficacy, and boosted therapeutic index. The delivery of drugs, particularly macromolecules, across the skin is one of the most strenuous obstacles in front of pharmaceutical scientists. Technology advancement has provided some opportunities to overcome this difficulty by utilising microneedle arrays, ablation, laser methods etc. However, associated uneasiness, painful sensation,...
Source: Current Drug Delivery - February 22, 2024 Category: Drugs & Pharmacology Authors: Deeksha Manchanda Manish Makhija Parijat Pandey Manu Sharma Source Type: research
Transfersomes: Recent Advances, Mechanisms, Exhaustive Applications, Clinical Trials, and Patents
Curr Drug Deliv. 2024 Feb 21. doi: 10.2174/0115672018295038240209055444. Online ahead of print.ABSTRACTA feasible nano transdermal delivery system generally intends to have specific ideal and distinct characteristics primarily for safety, clinical efficacy, and boosted therapeutic index. The delivery of drugs, particularly macromolecules, across the skin is one of the most strenuous obstacles in front of pharmaceutical scientists. Technology advancement has provided some opportunities to overcome this difficulty by utilising microneedle arrays, ablation, laser methods etc. However, associated uneasiness, painful sensation,...
Source: Current Drug Delivery - February 22, 2024 Category: Drugs & Pharmacology Authors: Deeksha Manchanda Manish Makhija Parijat Pandey Manu Sharma Source Type: research
Transfersomes: Recent Advances, Mechanisms, Exhaustive Applications, Clinical Trials, and Patents
Curr Drug Deliv. 2024 Feb 21. doi: 10.2174/0115672018295038240209055444. Online ahead of print.ABSTRACTA feasible nano transdermal delivery system generally intends to have specific ideal and distinct characteristics primarily for safety, clinical efficacy, and boosted therapeutic index. The delivery of drugs, particularly macromolecules, across the skin is one of the most strenuous obstacles in front of pharmaceutical scientists. Technology advancement has provided some opportunities to overcome this difficulty by utilising microneedle arrays, ablation, laser methods etc. However, associated uneasiness, painful sensation,...
Source: Current Drug Delivery - February 22, 2024 Category: Drugs & Pharmacology Authors: Deeksha Manchanda Manish Makhija Parijat Pandey Manu Sharma Source Type: research
Designing, Optimising, and Assessing a Novel Emulgel Containing Minoxidil for Controlled Drug Release, Incorporating Marine-based Polymers
CONCLUSION: Owing to the wide range of biological activities of fucoidan, the loaded active substance can be protected, and at the same time, its potency can be improved, resulting in effective treatment. Because fucoidan has diverse properties and potential, it will be widely used in the biomedical and pharmaceutical industries in the future.PMID:38362691 | DOI:10.2174/0115672018271502231226113423 (Source: Current Drug Delivery)
Source: Current Drug Delivery - February 16, 2024 Category: Drugs & Pharmacology Authors: Flowerlet Mathew A Mary Saral Source Type: research
Designing, Optimising, and Assessing a Novel Emulgel Containing Minoxidil for Controlled Drug Release, Incorporating Marine-based Polymers
CONCLUSION: Owing to the wide range of biological activities of fucoidan, the loaded active substance can be protected, and at the same time, its potency can be improved, resulting in effective treatment. Because fucoidan has diverse properties and potential, it will be widely used in the biomedical and pharmaceutical industries in the future.PMID:38362691 | DOI:10.2174/0115672018271502231226113423 (Source: Current Drug Delivery)
Source: Current Drug Delivery - February 16, 2024 Category: Drugs & Pharmacology Authors: Flowerlet Mathew A Mary Saral Source Type: research
Designing, Optimising, and Assessing a Novel Emulgel Containing Minoxidil for Controlled Drug Release, Incorporating Marine-based Polymers
CONCLUSION: Owing to the wide range of biological activities of fucoidan, the loaded active substance can be protected, and at the same time, its potency can be improved, resulting in effective treatment. Because fucoidan has diverse properties and potential, it will be widely used in the biomedical and pharmaceutical industries in the future.PMID:38362691 | DOI:10.2174/0115672018271502231226113423 (Source: Current Drug Delivery)
Source: Current Drug Delivery - February 16, 2024 Category: Drugs & Pharmacology Authors: Flowerlet Mathew A Mary Saral Source Type: research
Designing, Optimising, and Assessing a Novel Emulgel Containing Minoxidil for Controlled Drug Release, Incorporating Marine-based Polymers
CONCLUSION: Owing to the wide range of biological activities of fucoidan, the loaded active substance can be protected, and at the same time, its potency can be improved, resulting in effective treatment. Because fucoidan has diverse properties and potential, it will be widely used in the biomedical and pharmaceutical industries in the future.PMID:38362691 | DOI:10.2174/0115672018271502231226113423 (Source: Current Drug Delivery)
Source: Current Drug Delivery - February 16, 2024 Category: Drugs & Pharmacology Authors: Flowerlet Mathew A Mary Saral Source Type: research
Designing, Optimising, and Assessing a Novel Emulgel Containing Minoxidil for Controlled Drug Release, Incorporating Marine-based Polymers
CONCLUSION: Owing to the wide range of biological activities of fucoidan, the loaded active substance can be protected, and at the same time, its potency can be improved, resulting in effective treatment. Because fucoidan has diverse properties and potential, it will be widely used in the biomedical and pharmaceutical industries in the future.PMID:38362691 | DOI:10.2174/0115672018271502231226113423 (Source: Current Drug Delivery)
Source: Current Drug Delivery - February 16, 2024 Category: Drugs & Pharmacology Authors: Flowerlet Mathew A Mary Saral Source Type: research
Preparation, Characterization, and Evaluation of Mesoporous Silica Nanoparticles in Enhancing Oral Bioavailability of Poorly Water-Soluble Drugs
CONCLUSION: MSNs have the potential to enhance the oral bioavailability of poorly water-soluble drugs by accelerating the drug dissolution rate.PMID:38310438 | DOI:10.2174/0115672018273792240101062603 (Source: Current Drug Delivery)
Source: Current Drug Delivery - February 4, 2024 Category: Drugs & Pharmacology Authors: Hong Zhang Fanjiao Zuo Boyao Wang Xilong Qiu Source Type: research
Intelligent Drug Delivery: Pioneering Stimuli-Responsive Systems to Revolutionize Disease Management- An In-depth Exploration
Curr Drug Deliv. 2024 Jan 26. doi: 10.2174/0115672018278641231221051359. Online ahead of print.ABSTRACTIn recent years, there has been an escalating interest in stimuli-responsive drug delivery systems (SRDDS) due to their ability to revolutionize the delivery of therapeutics. SRDDSs offer a multitude of benefits in comparison to conventional drug delivery systems (DDS), including spatiotemporal control of drug release, targeted delivery, and improved therapeutic efficacy. The development of various classes of stimuli-responsive DDS, such as pH-responsive, temperature-responsive, photo-responsive, redox responsive systems,...
Source: Current Drug Delivery - February 4, 2024 Category: Drugs & Pharmacology Authors: Badarinadh Kallepalli Unnati Garg Neha Jain Rohan Nagpal Sakshi Malhotra Triveni Tiwari Shreya Kaul Upendra Nagaich Source Type: research
Novel Biomaterials Based Strategies for Neurodegeneration: Recent Advancements and Future Prospects
Curr Drug Deliv. 2024 Jan 19. doi: 10.2174/0115672018275382231215063052. Online ahead of print.ABSTRACTNeurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease, pose significant challenges for effective treatment due to the complex nature of the central nervous system and the limited delivery of therapeutic agents to the brain. Biomaterial-based drug delivery systems offer promising strategies to overcome these challenges and improve therapeutic outcomes. These systems utilize various biomaterials, such as nanoparticles, hydrogels, and implants, to deliver drugs, genes, or ce...
Source: Current Drug Delivery - February 4, 2024 Category: Drugs & Pharmacology Authors: Dilpreet Singh Sanjay Nagdev Source Type: research
Effective Strategies in Designing Chitosan-hyaluronic Acid Nanocarriers: From Synthesis to Drug Delivery Towards Chemotherapy
This article aims to provide a comprehensive analysis of CSHANp, focusing on its characteristics, production techniques, applications, and future prospects.PMID:38310441 | DOI:10.2174/0115672018275983231207101222 (Source: Current Drug Delivery)
Source: Current Drug Delivery - February 4, 2024 Category: Drugs & Pharmacology Authors: Long-Quy Hong Thao N T Ho Son T Cu Lien Tuyet Ngan Tran Ngoc Quyen Tien T Dang Source Type: research
Mannose: A Promising Player in Clinical and Biomedical Applications
Curr Drug Deliv. 2024 Jan 15. doi: 10.2174/0115672018275954231220101637. Online ahead of print.ABSTRACTMannose, an isomer of glucose, exhibits a distinct molecular structure with the same formula but a different atom arrangement, contributing to its specific biological functions. Widely distributed in body fluids and tissues, particularly in the nervous system, skin, testes, and retinas, mannose plays a crucial role as a direct precursor for glycoprotein synthesis. Glycoproteins, essential for immune regulation and glycosylation processes, underscore the significance of mannose in these physiological activities. The clinic...
Source: Current Drug Delivery - February 4, 2024 Category: Drugs & Pharmacology Authors: Sijing Chen Kana Wang Qiao Wang Source Type: research
Preparation, Characterization, and Evaluation of Mesoporous Silica Nanoparticles in Enhancing Oral Bioavailability of Poorly Water-Soluble Drugs
CONCLUSION: MSNs have the potential to enhance the oral bioavailability of poorly water-soluble drugs by accelerating the drug dissolution rate.PMID:38310438 | DOI:10.2174/0115672018273792240101062603 (Source: Current Drug Delivery)
Source: Current Drug Delivery - February 4, 2024 Category: Drugs & Pharmacology Authors: Hong Zhang Fanjiao Zuo Boyao Wang Xilong Qiu Source Type: research
