Nano-platform Strategies of Herbal Components for the management of Rheumatoid Arthritis: A Review on the Battle for Next-Generation Formulations
CONCLUSION: In conclusion, there are many anti-arthritic herbal and synthetic medicine available in the market that are currently used in the treatment of RA. However, chronic use of these medications may result in a variety of side effects. Because therapy for RA is frequently necessary for the rest of ones life. The use of natural products may be a better option for RA management. These phytoconstituents, however, have several disadvantages, including limited bioavailability, low stability, and the need for a greater dosage. These problems can be rectified by using nano-technology.PMID:37622715 | DOI:10.2174/156720182166...
Source: Current Drug Delivery - August 25, 2023 Category: Drugs & Pharmacology Authors: Jyoti Prabha Mohit Kumar Devesh Kumar Shruti Chopra Amit Bhatia Source Type: research
Nano-platform Strategies of Herbal Components for the management of Rheumatoid Arthritis: A Review on the Battle for Next-Generation Formulations
CONCLUSION: In conclusion, there are many anti-arthritic herbal and synthetic medicine available in the market that are currently used in the treatment of RA. However, chronic use of these medications may result in a variety of side effects. Because therapy for RA is frequently necessary for the rest of ones life. The use of natural products may be a better option for RA management. These phytoconstituents, however, have several disadvantages, including limited bioavailability, low stability, and the need for a greater dosage. These problems can be rectified by using nano-technology.PMID:37622715 | DOI:10.2174/156720182166...
Source: Current Drug Delivery - August 25, 2023 Category: Drugs & Pharmacology Authors: Jyoti Prabha Mohit Kumar Devesh Kumar Shruti Chopra Amit Bhatia Source Type: research
Nano-platform Strategies of Herbal Components for the management of Rheumatoid Arthritis: A Review on the Battle for Next-Generation Formulations
CONCLUSION: In conclusion, there are many anti-arthritic herbal and synthetic medicine available in the market that are currently used in the treatment of RA. However, chronic use of these medications may result in a variety of side effects. Because therapy for RA is frequently necessary for the rest of ones life. The use of natural products may be a better option for RA management. These phytoconstituents, however, have several disadvantages, including limited bioavailability, low stability, and the need for a greater dosage. These problems can be rectified by using nano-technology.PMID:37622715 | DOI:10.2174/156720182166...
Source: Current Drug Delivery - August 25, 2023 Category: Drugs & Pharmacology Authors: Jyoti Prabha Mohit Kumar Devesh Kumar Shruti Chopra Amit Bhatia Source Type: research
Nano-platform Strategies of Herbal Components for the management of Rheumatoid Arthritis: A Review on the Battle for Next-Generation Formulations
CONCLUSION: In conclusion, there are many anti-arthritic herbal and synthetic medicine available in the market that are currently used in the treatment of RA. However, chronic use of these medications may result in a variety of side effects. Because therapy for RA is frequently necessary for the rest of ones life. The use of natural products may be a better option for RA management. These phytoconstituents, however, have several disadvantages, including limited bioavailability, low stability, and the need for a greater dosage. These problems can be rectified by using nano-technology.PMID:37622715 | DOI:10.2174/156720182166...
Source: Current Drug Delivery - August 25, 2023 Category: Drugs & Pharmacology Authors: Jyoti Prabha Mohit Kumar Devesh Kumar Shruti Chopra Amit Bhatia Source Type: research
Nano-platform Strategies of Herbal Components for the management of Rheumatoid Arthritis: A Review on the Battle for Next-Generation Formulations
CONCLUSION: In conclusion, there are many anti-arthritic herbal and synthetic medicine available in the market that are currently used in the treatment of RA. However, chronic use of these medications may result in a variety of side effects. Because therapy for RA is frequently necessary for the rest of ones life. The use of natural products may be a better option for RA management. These phytoconstituents, however, have several disadvantages, including limited bioavailability, low stability, and the need for a greater dosage. These problems can be rectified by using nano-technology.PMID:37622715 | DOI:10.2174/156720182166...
Source: Current Drug Delivery - August 25, 2023 Category: Drugs & Pharmacology Authors: Jyoti Prabha Mohit Kumar Devesh Kumar Shruti Chopra Amit Bhatia Source Type: research
Dysprosium-containing cobalt sulfide nanoparticles as anticancer drug carriers
CONCLUSION: The ultrasmall nanoparticles possess a size suitable for drug delivery and are dispersed well in the aqueous medium. The release of the loaded 5-fluorouracil is slow and sustained. The anticancer activity of the drug-loaded nanocarrier shows an increase in efficacy, and the cytotoxicity is appreciable due to the controlled release. The nanocarriers show multi-functional characteristics, i.e., magnetic and NIR-absorbing, and are promising drug delivery agents.PMID:37592787 | DOI:10.2174/1567201821666230817122011 (Source: Current Drug Delivery)
Source: Current Drug Delivery - August 18, 2023 Category: Drugs & Pharmacology Authors: Govindaraj Sri Varalakshmi Charan Singh Pawar Varnitha Manikantan Archana Sumohan Pillai Aleyamma Alexander Bose Allben Akash N Rajendra Prasad Israel V M V Enoch Source Type: research
Dysprosium-containing cobalt sulfide nanoparticles as anticancer drug carriers
CONCLUSION: The ultrasmall nanoparticles possess a size suitable for drug delivery and are dispersed well in the aqueous medium. The release of the loaded 5-fluorouracil is slow and sustained. The anticancer activity of the drug-loaded nanocarrier shows an increase in efficacy, and the cytotoxicity is appreciable due to the controlled release. The nanocarriers show multi-functional characteristics, i.e., magnetic and NIR-absorbing, and are promising drug delivery agents.PMID:37592787 | DOI:10.2174/1567201821666230817122011 (Source: Current Drug Delivery)
Source: Current Drug Delivery - August 18, 2023 Category: Drugs & Pharmacology Authors: Govindaraj Sri Varalakshmi Charan Singh Pawar Varnitha Manikantan Archana Sumohan Pillai Aleyamma Alexander Bose Allben Akash N Rajendra Prasad Israel V M V Enoch Source Type: research
Dysprosium-containing cobalt sulfide nanoparticles as anticancer drug carriers
CONCLUSION: The ultrasmall nanoparticles possess a size suitable for drug delivery and are dispersed well in the aqueous medium. The release of the loaded 5-fluorouracil is slow and sustained. The anticancer activity of the drug-loaded nanocarrier shows an increase in efficacy, and the cytotoxicity is appreciable due to the controlled release. The nanocarriers show multi-functional characteristics, i.e., magnetic and NIR-absorbing, and are promising drug delivery agents.PMID:37592787 | DOI:10.2174/1567201821666230817122011 (Source: Current Drug Delivery)
Source: Current Drug Delivery - August 18, 2023 Category: Drugs & Pharmacology Authors: Govindaraj Sri Varalakshmi Charan Singh Pawar Varnitha Manikantan Archana Sumohan Pillai Aleyamma Alexander Bose Allben Akash N Rajendra Prasad Israel V M V Enoch Source Type: research
Dysprosium-containing cobalt sulfide nanoparticles as anticancer drug carriers
CONCLUSION: The ultrasmall nanoparticles possess a size suitable for drug delivery and are dispersed well in the aqueous medium. The release of the loaded 5-fluorouracil is slow and sustained. The anticancer activity of the drug-loaded nanocarrier shows an increase in efficacy, and the cytotoxicity is appreciable due to the controlled release. The nanocarriers show multi-functional characteristics, i.e., magnetic and NIR-absorbing, and are promising drug delivery agents.PMID:37592787 | DOI:10.2174/1567201821666230817122011 (Source: Current Drug Delivery)
Source: Current Drug Delivery - August 18, 2023 Category: Drugs & Pharmacology Authors: Govindaraj Sri Varalakshmi Charan Singh Pawar Varnitha Manikantan Archana Sumohan Pillai Aleyamma Alexander Bose Allben Akash N Rajendra Prasad Israel V M V Enoch Source Type: research
Dysprosium-containing cobalt sulfide nanoparticles as anticancer drug carriers
CONCLUSION: The ultrasmall nanoparticles possess a size suitable for drug delivery and are dispersed well in the aqueous medium. The release of the loaded 5-fluorouracil is slow and sustained. The anticancer activity of the drug-loaded nanocarrier shows an increase in efficacy, and the cytotoxicity is appreciable due to the controlled release. The nanocarriers show multi-functional characteristics, i.e., magnetic and NIR-absorbing, and are promising drug delivery agents.PMID:37592787 | DOI:10.2174/1567201821666230817122011 (Source: Current Drug Delivery)
Source: Current Drug Delivery - August 18, 2023 Category: Drugs & Pharmacology Authors: Govindaraj Sri Varalakshmi Charan Singh Pawar Varnitha Manikantan Archana Sumohan Pillai Aleyamma Alexander Bose Allben Akash N Rajendra Prasad Israel V M V Enoch Source Type: research
Dysprosium-containing cobalt sulfide nanoparticles as anticancer drug carriers
CONCLUSION: The ultrasmall nanoparticles possess a size suitable for drug delivery and are dispersed well in the aqueous medium. The release of the loaded 5-fluorouracil is slow and sustained. The anticancer activity of the drug-loaded nanocarrier shows an increase in efficacy, and the cytotoxicity is appreciable due to the controlled release. The nanocarriers show multi-functional characteristics, i.e., magnetic and NIR-absorbing, and are promising drug delivery agents.PMID:37592787 | DOI:10.2174/1567201821666230817122011 (Source: Current Drug Delivery)
Source: Current Drug Delivery - August 18, 2023 Category: Drugs & Pharmacology Authors: Govindaraj Sri Varalakshmi Charan Singh Pawar Varnitha Manikantan Archana Sumohan Pillai Aleyamma Alexander Bose Allben Akash N Rajendra Prasad Israel V M V Enoch Source Type: research
Integrated animal experiments and network pharmacology for investigating therapeutic effect of celastrol-loaded liposomes on NAFLD
CONCLUSION: Celastrol has the potential to treat NAFLD, and its possible targets have been identified through network pharmacological screening, which provides a certain basis for the follow-up researches.PMID:37565560 | DOI:10.2174/1567201821666230810094643 (Source: Current Drug Delivery)
Source: Current Drug Delivery - August 11, 2023 Category: Drugs & Pharmacology Authors: Jingbin Shi Ninghui Ma Ningchao Luo Jingyi Huang Shujun Xu Yang Xiong Source Type: research
A Novel Etanercept-Loaded Nano-emulsion for Targeted Treatment of Inflammatory Arthritis via Draining Lymph Node
CONCLUSION: NEs/EN effectively improve the effectiveness of EN in the treatment of RA. Our work provides an experimental foundation for expanding the clinical application of EN.PMID:37565561 | DOI:10.2174/1567201821666230810115230 (Source: Current Drug Delivery)
Source: Current Drug Delivery - August 11, 2023 Category: Drugs & Pharmacology Authors: Chenglong Li Guanting Lu Yue Jiang Huaiyu Su Chen Li Source Type: research
Integrated animal experiments and network pharmacology for investigating therapeutic effect of celastrol-loaded liposomes on NAFLD
CONCLUSION: Celastrol has the potential to treat NAFLD, and its possible targets have been identified through network pharmacological screening, which provides a certain basis for the follow-up researches.PMID:37565560 | DOI:10.2174/1567201821666230810094643 (Source: Current Drug Delivery)
Source: Current Drug Delivery - August 11, 2023 Category: Drugs & Pharmacology Authors: Jingbin Shi Ninghui Ma Ningchao Luo Jingyi Huang Shujun Xu Yang Xiong Source Type: research
A Novel Etanercept-Loaded Nano-emulsion for Targeted Treatment of Inflammatory Arthritis via Draining Lymph Node
CONCLUSION: NEs/EN effectively improve the effectiveness of EN in the treatment of RA. Our work provides an experimental foundation for expanding the clinical application of EN.PMID:37565561 | DOI:10.2174/1567201821666230810115230 (Source: Current Drug Delivery)
Source: Current Drug Delivery - August 11, 2023 Category: Drugs & Pharmacology Authors: Chenglong Li Guanting Lu Yue Jiang Huaiyu Su Chen Li Source Type: research