Nanocarrier Mediated Intranasal Drug Delivery Systems for the Management of Parkinsonism: A Review
Curr Drug Deliv. 2023 Jun 16. doi: 10.2174/1567201820666230523114259. Online ahead of print.ABSTRACTThe transport of drugs to the brain becomes a key concern when treating disorders of the central nervous system. Parkinsonism is one of the major concerns across the world populations, which causes difficulty in coordination and balance. However, the blood-brain barrier is a significant barrier to achieving optimal brain concentration through oral, transdermal, and intravenous routes of administration. The intranasal route with nanocarrier-based formulations has shown potential for managing Parkinsonism disorder (PD). Direct...
Source: Current Drug Delivery - June 27, 2023 Category: Drugs & Pharmacology Authors: Archita Kapoor Abdul Hafeez Poonam Kushwaha Source Type: research

Nanocarrier Mediated Intranasal Drug Delivery Systems for the Management of Parkinsonism: A Review
Curr Drug Deliv. 2023 Jun 16. doi: 10.2174/1567201820666230523114259. Online ahead of print.ABSTRACTThe transport of drugs to the brain becomes a key concern when treating disorders of the central nervous system. Parkinsonism is one of the major concerns across the world populations, which causes difficulty in coordination and balance. However, the blood-brain barrier is a significant barrier to achieving optimal brain concentration through oral, transdermal, and intravenous routes of administration. The intranasal route with nanocarrier-based formulations has shown potential for managing Parkinsonism disorder (PD). Direct...
Source: Current Drug Delivery - June 27, 2023 Category: Drugs & Pharmacology Authors: Archita Kapoor Abdul Hafeez Poonam Kushwaha Source Type: research

Current Landscape of Therapeutics for the Management of Hypertension - A Review
Curr Drug Deliv. 2023 Jun 23. doi: 10.2174/1567201820666230623121433. Online ahead of print.ABSTRACTHypertension is a critical health problem. It is also the primary cause of coronary heart disease, stroke, and renal vascular disease. The use of herbal drugs in the management of any disease is increasing. They are considered the best immune booster to fight against several types of diseases. To date, the demand for herbal drugs has been increasing because of their excellent properties. This review highlights antihypertensive drugs, polyphenols, and synbiotics for managing hypertension. Evidence is mounting in favour of mor...
Source: Current Drug Delivery - June 26, 2023 Category: Drugs & Pharmacology Authors: Neda Fatima Sumel Ashique Aakash Upadhyay Shubneesh Kumar Himanshu Kumar Nitish Kumar Prashant Kumar Source Type: research

Current Landscape of Therapeutics for the Management of Hypertension - A Review
Curr Drug Deliv. 2023 Jun 23. doi: 10.2174/1567201820666230623121433. Online ahead of print.ABSTRACTHypertension is a critical health problem. It is also the primary cause of coronary heart disease, stroke, and renal vascular disease. The use of herbal drugs in the management of any disease is increasing. They are considered the best immune booster to fight against several types of diseases. To date, the demand for herbal drugs has been increasing because of their excellent properties. This review highlights antihypertensive drugs, polyphenols, and synbiotics for managing hypertension. Evidence is mounting in favour of mor...
Source: Current Drug Delivery - June 26, 2023 Category: Drugs & Pharmacology Authors: Neda Fatima Sumel Ashique Aakash Upadhyay Shubneesh Kumar Himanshu Kumar Nitish Kumar Prashant Kumar Source Type: research

Improved Antitumor Efficacy of a Dextran-based Docetaxel-Coupled Conjugate Against Triple-Negative Breast Cancer
CONCLUSION: This dual-drug C-DDD has the potential to become a candidate for clinical application through the optimization of the linker.PMID:37349996 | DOI:10.2174/1567201820666230622105503 (Source: Current Drug Delivery)
Source: Current Drug Delivery - June 23, 2023 Category: Drugs & Pharmacology Authors: Hongshuai Lv Weiping Jia Peng Dong Jiaojiao Liu Si Wang Xiaohai Li Jinghua Hu Ling Zhao Yikang Shi Source Type: research