Utility of Urodynamics in Children with Dysfunctional Voiding
AbstractPurpose of ReviewThis review will allow the reader to understand the rationale for urodynamic testing in a child who is neurologically intact and is suspected of having dysfunctional voiding. We will look to define criteria that will prevent the overuse and unnecessary use of this invasive test in children.Recent findingsThe literature does not support the routine use of invasive urodynamics for children with urge syndrome but does support its use for elucidation of dysfunctional voiding abnormalities in neurologically intact children.SummaryThe child with functional voiding issues presents itself with factors that...
Source: Current Bladder Dysfunction Reports - September 1, 2018 Category: Urology & Nephrology Source Type: research

Prevalence and Cost of Catheters to Manage Neurogenic Bladder
AbstractPurpose of ReviewIn this review, we examine the current literature to address the epidemiology of catheters for managing neurogenic bladder. We will address the epidemiology of conditions associated with neurogenic bladder, including multiple sclerosis, spinal cord injury, Parkinson ’s disease, stroke, and spina bifida. Rates of utilization of various catheter strategies, including indwelling urethral catheter, suprapubic catheter, and intermittent catheterization rates will be reviewed. Lastly, we examine the cost considerations between and within each type of strategy.Recent FindingsManagement strategies for ne...
Source: Current Bladder Dysfunction Reports - August 25, 2018 Category: Urology & Nephrology Source Type: research

Contemporary Treatment of Detrusor Sphincter Dyssynergia: a Systematic Review
AbstractPurpose of ReviewTo systematically review the literature to determine outcomes of detrusor sphincter dyssynergia (DSD) treatments. DSD can present in patients with neurogenic bladder due to a variety of conditions, but no treatment guidelines currently exist. Ovid Medline, Embase, PubMed, and Web of Science were searched within the last 10  years for “detrusor sphincter dyssynergia.” Results were independently reviewed by two coauthors for inclusion using the Preferred Reporting Items for Systematic Reviews and Meta-analysis Protocols (PRISMA) guidelines. Exclusion criteria were pediatric populations, reviews,...
Source: Current Bladder Dysfunction Reports - August 15, 2018 Category: Urology & Nephrology Source Type: research

Safely Avoiding Surgery in Adult Neurogenic Bladder
AbstractPurposeTo evaluate the literature regarding non-surgical management of adult patients with high-pressure neurogenic bladder.Recent FindingsEstablished therapies that facilitate bladder storage and emptying include anticholinergic medications, intradetrusor onabotulinum toxin injection, and intermittent catheterization. Application of these strategies to patients with elevated detrusor leak point pressures has shown improvement in bladder compliance and preservation of renal function. New interventions in the algorithm of management of patients with poor bladder compliance, such as beta-3 agonists and sacral neuromo...
Source: Current Bladder Dysfunction Reports - August 14, 2018 Category: Urology & Nephrology Source Type: research

Does Urodynamics Impact the Outcomes of Third-line Therapy of Refractory OAB (or Refractory Urgency Urinary Incontinence)?
AbstractPurpose of ReviewOveractive bladder (OAB) is highly prevalent with increasing age. Conservative management including lifestyle adaptation, controlled fluid intake, and bladder training are considered first-line therapeutic options. Second-line options are medication such as antimuscarinics or beta-3 adrenergic receptor agonists. Therapy refractory patients should be referred to a specialist for further evaluation.Recent FindingsIt currently remains unclear if patients should undergo routine urodynamic investigation (UDI) before offering third-line therapies like sacral neuromodulation (SNM) or intradetrusor injecti...
Source: Current Bladder Dysfunction Reports - August 10, 2018 Category: Urology & Nephrology Source Type: research

Neurogenic Bladder: Recurrent Urinary Tract Infections —Beyond Antibiotics
AbstractPurpose of ReviewOur goal was to identify evidenced-based strategies to prevent and treat patients with neurogenic bladder who suffer from recurrent urinary tract infections. We focused on therapy beyond standard antibiotics to address a multitude of factors implicated in these complex infections.Recent FindingsAnatomic and functional components specific to neurogenic bladder contribute to the risk of infection and require close clinical monitoring. The host-pathogen interaction is one that allows for colonization of bacteria in the bladder. We recognize that bacteriuria in the neurogenic bladder population does no...
Source: Current Bladder Dysfunction Reports - August 9, 2018 Category: Urology & Nephrology Source Type: research

The Role of Chemical Sphincterotomy with Urethral Botulinum Toxin Injection in Patients with Neurogenic and Non-neurogenic Failure to Empty
AbstractPurpose of ReviewThis review focuses on the evidence for injection of botulinum A toxin (BTX) to the external urinary sphincter for management of impaired bladder emptying secondary to neurogenic conditions such as detrusor sphincter dyssynergia (DSD) and non-neurogenic conditions such as dysfunctional voiding (DV). The application of urethral BTX for patients with impaired emptying secondary to detrusor underactivity will also be discussed. The goal of the review is to comprehensively analyze the evidence surrounding urethral BTX in this context and help guide decision-making.Recent FindingsA robust body of litera...
Source: Current Bladder Dysfunction Reports - July 18, 2018 Category: Urology & Nephrology Source Type: research

Stress Urinary Incontinence Management in the Patient With Overactive Bladder
AbstractPurpose of the ReviewMixed urinary incontinence is a common diagnosis that has significant impact on patient quality of life and can be more bothersome to patients compared to pure stress incontinence. Given the complexity of concomitant stress incontinence and overactive bladder symptoms, mixed urinary incontinence can often present as a clinically challenging scenario for treating physicians across different subspecialties and primary care medicine. In this review, we discuss the importance of a judicious evaluation and the utility of deciphering stress-predominant versus urge-predominant urinary incontinence in ...
Source: Current Bladder Dysfunction Reports - July 7, 2018 Category: Urology & Nephrology Source Type: research

Management of Recurrent Stress Urinary Incontinence After Failed Mid-Urethral Sling Placement
AbstractPurpose of ReviewOur objective is to review the current literature on recurrent stress urinary incontinence after mid-urethral sling placement, focusing on evidence-based management considerations for this complex clinical problem.Recent FindingsConservative, minimally invasive surgical therapies are currently available for management of persistent or recurrent SUI after a previous mid-urethral sling (MUS).SummaryOur review of the literature does not show a clear benefit of one approach over others and emphasizes that the ideal management for these complex patients should be determined using an individualized appro...
Source: Current Bladder Dysfunction Reports - July 7, 2018 Category: Urology & Nephrology Source Type: research

Utility of Urodynamics in Children with Dysfunctional Voiding
AbstractPurpose of ReviewThis review will allow the reader to understand the rationale for urodynamic testing in a child who is neurologically intact and is suspected of having dysfunctional voiding. We will look to define criteria that will prevent the overuse and unnecessary use of this invasive test in children.Recent findingsThe literature does not support the routine use of invasive urodynamics for children with urge syndrome but does support its use for elucidation of dysfunctional voiding abnormalities in neurologically intact children.SummaryThe child with functional voiding issues presents itself with factors that...
Source: Current Bladder Dysfunction Reports - June 27, 2018 Category: Urology & Nephrology Source Type: research

Cost-Effectiveness of Third-Line Therapies for Overactive Bladder
AbstractPurpose of ReviewWhile third-line therapies for overactive bladder and urgency urinary incontinence are well-described in guideline statements, there is little offered in guidance when it comes to selecting a particular intervention amongst these therapies for patients. Data regarding efficacy has a body of literature that takes sides on all fronts, making efficacy of these interventions a topic of continued debate. An ever-present factor for consideration also remains —cost of therapy. This review examines current data available for cost of third-line therapies.Recent FindingsIn this body of literature regarding...
Source: Current Bladder Dysfunction Reports - June 22, 2018 Category: Urology & Nephrology Source Type: research

Apical Prolapse: Is There a Best Approach?
We present some of the latest literature to help guide surgeons in clinical decision-making with respect to approach and type of suspension procedure.Recent FindingsMore hysterectomies for prolapse are being done with special attention to the apex as this is now an endorsed quality measure by NQF. The OPTIMAL Trial showed no difference in outcomes for uterosacral ligament suspension and sacrospinous ligament fixation. Sacrocolpopexy with mesh remains the most durable repair available but represents a more invasive approach than vaginal procedures.SummaryVaginal approaches continue to play a role in apical suspension especi...
Source: Current Bladder Dysfunction Reports - June 21, 2018 Category: Urology & Nephrology Source Type: research

AUA Guidelines on Stress Urinary Incontinence: What Is New in the Guidelines?
AbstractPurpose of the ReviewStress urinary incontinence is a prevalent condition that can have a detrimental impact on the quality of life of affected individuals. Once judicious assessment of degree of bother the symptoms are causing a patient is performed, it is crucial to incorporate appropriate counseling and patient education as part of symptom management. Treatment modalities have evolved over the last several decades, and both nonsurgical and surgical treatment options should be discussed. This review highlights the recently published guidelines update from the American Urological Association (AUA) and the Society ...
Source: Current Bladder Dysfunction Reports - June 15, 2018 Category: Urology & Nephrology Source Type: research

Managing of Lower Urinary Tract Dysfunction Following Stroke
AbstractPurpose of ReviewThis comprehensive up-to-date review will synthesise relevant available literature on the topic of post-stroke lower urinary tract dysfunction (LUTD). Topics include epidemiology of LUTD, LUTD as a prognostic indicator for stroke recovery, urinary incontinence and retention, correlations between brain lesion localisation and LUTD, causes of LUTD, medical complications due to LUTD, diagnostics and contemporary management of LUTD in stroke patients.Recent FindingsLUTD frequently occurs after a stroke and is associated with poor overall functional outcome, increased institutionalisation and mortality ...
Source: Current Bladder Dysfunction Reports - June 11, 2018 Category: Urology & Nephrology Source Type: research

Post-Implant Management of Sacral Neuromodulation
AbstractPurpose of ReviewPost-implant management of sacral neuromodulation is crucial in ensuring the success of therapy. Common management dilemmas include various follow-up schedules, circumstances related to pregnancy, and the possible need for magnetic resonance imaging. Moreover, complications such as lack of or declining efficacy over time, painful stimulation, pain at the implantable pulse generator site, and wound complications need to properly be handled.Recent FindingsIn this chapter, each of these above-mentioned scenarios is explored, and the literature concerning them is reviewed. Tips regarding dealing with m...
Source: Current Bladder Dysfunction Reports - June 7, 2018 Category: Urology & Nephrology Source Type: research