Pregnancy After Lower Urinary Tract Reconstruction: Considerations for Prenatal Management and Delivery
AbstractPurpose of reviewThe goal of this work is to review the existing evidence base regarding the prenatal and delivery care for pregnant patients with a history of lower urinary tract reconstruction (LUTR). The primary audience of this work is both urologists and obstetricians who will be involved in the management of patients with LUTR.Recent findingsThe literature surrounding this topic is limited due to the small patient population. However, given significant advancements in care for patients with spinal dysraphism and complex urogenital anatomy these patients are living longer and are having richer social lives wit...
Source: Current Bladder Dysfunction Reports - November 10, 2023 Category: Urology & Nephrology Source Type: research

Imaging in Pelvic Organ Prolapse — When Should It Be Routine?
AbstractPurpose of ReviewImaging for pelvic organ prolapse (POP) has only been included in the guidelines for complex cases but with no clear definition for what is considered a complex case. We reviewed literature from the last 5  years describing the use of various imaging modalities in the diagnosis and evaluation of POP to explore emerging recommendations and better define when imaging should be considered in the evaluation of POP. We discuss each of the imaging modalities in terms of cost, availability, specifics on pos itioning during image capture, and their measurement parameters.Recent FindingsCystograms and defe...
Source: Current Bladder Dysfunction Reports - November 3, 2023 Category: Urology & Nephrology Source Type: research

Management of Urgency Urinary Incontinence After Orthotopic Neobladder
AbstractPurpose of ReviewThe current literature available to providers on urgency urinary incontinence in orthotopic neobladder patients will be reviewed.Recent FindingsIn this review, we will examine the most recent studies evaluating potential therapies for urgency urinary incontinence in neobladder patients.SummaryUrgency urinary incontinence in patients with neobladders is a challenging symptom to manage for both patients and providers, both due to the pathophysiology as well as a lack of data on effective therapies. Given the similar symptom profile to patients with overactive bladder as well as comparable functional ...
Source: Current Bladder Dysfunction Reports - November 1, 2023 Category: Urology & Nephrology Source Type: research

Navigating the Diagnostic Maze: Unraveling the Non-invasive Evaluation of Bladder Outlet Obstruction in Men —a Comprehensive Systematic Review
This study aimed to comprehensively review non-invasive methods for diagnosing BOO, primarily in cases related to benign prostatic hyperplasia.Recent FindingsA systematic literature review was conducted on PubMed from January 2016 to November 2022, focusing on non-invasive tests and lower urinary tract symptoms (LUTS) or bladder outlet obstruction (BOO) in men. A total of 2520 results were included, resulting in 1620 unique findings after removing duplicates. From these, 263 abstracts were thoroughly evaluated, leading to a detailed review of 80 full-text articles and their references. The review identified numerous cuttin...
Source: Current Bladder Dysfunction Reports - October 28, 2023 Category: Urology & Nephrology Source Type: research

Botulinumtoxin Injection Versus Augmentation Cystoplasty for Neurogenic Bladder: Where Do We Stand?
AbstractPurpose of ReviewPatients with neurogenic bladder often present with overactive, low capacity, and poorly compliant bladders with discoordination of their internal and external urethral sphincters. As a result of poor compliance, high detrusor pressures can cause reflux into the upper tracts. This constellation of findings can also cause bothersome lower urinary tract symptoms. There are various modes of management for patients with neurogenic bladder ranging from conservative methods to major reconstructive surgery in efforts to prevent upper tract deterioration and to treat voiding dysfunction. This paper aims to...
Source: Current Bladder Dysfunction Reports - October 26, 2023 Category: Urology & Nephrology Source Type: research

Interstitial Cystitis/Bladder Pain Syndrome: Role of Bladder Inflammation in Bladder Function
AbstractPurpose of ReviewWe performed recent literature review with the aim to address the updates in diagnosis and management of interstitial cystitis/bladder pain syndrome (IC/BPS).Recent FindingsThere are multiple recently published studies that collectively lead to an organized stepwise plan for diagnosis and management of IC/BPS.SummaryIC/BPS is a common health condition that can be managed efficiently if the appropriate steps are taken in diagnosis and management. (Source: Current Bladder Dysfunction Reports)
Source: Current Bladder Dysfunction Reports - October 25, 2023 Category: Urology & Nephrology Source Type: research

Bladder Pain Syndrome Associated with Interstitial Cystitis: Recent Research and Treatment Options
This article reports recently published research in diagnosis and treatment of IC/BPS.Recent FindingsCurrent research shows that the syndrome is likely heterogeneous, with different pathogeneses, clinical characteristics, cystoscopic findings, and characteristics of urine biomarkers. Chronic bladder inflammation results in deficits in the bladder urothelial barrier in addition to increased apoptosis and impaired regeneration of urothelial cells, causing bladder pain symptoms and urinary frequency and urgency. The initial therapeutic approach is conservative treatment with lifestyle modification, anti-inflammatory drugs, an...
Source: Current Bladder Dysfunction Reports - October 25, 2023 Category: Urology & Nephrology Source Type: research

Management of Patients with Detrusor Hyperactivity with Impaired Contractility
AbstractPurpose of ReviewDetrusor hyperactivity and impaired contractility (DHIC) is a common condition seen in elderly patients who suffered from lower urinary tract symptoms. Hypothetical pathogenesis and debatable definition of diagnosis may have caused difficulties in developing effective treatments through the past decades. In this review, we aim to discuss currently available treatments of DHIC.Recent FindingsMirabegron was an effective treatment option with subjective symptom improvement and reduced post-void residual volume at 6 months. Intravesical injection of onabotulinumtoxinA improved overactive bladder (OAB) ...
Source: Current Bladder Dysfunction Reports - October 23, 2023 Category: Urology & Nephrology Source Type: research

Role of Intravesical Ozone in the Management of BPS/Interstitial Cystitis
AbstractPurpose of ReviewIn this review, studies and mechanisms of action relative to intravesical ozone in Bladder Pain Syndrome/Interstitial Cystitis (IC/BPS) will be summarized and correlated with pathologies of chronic pelvic pain in animal models and clinical trials.Recent FindingsSome studies have investigated intravesical ozone therapy in view of the disadvantages of conventional interventions and the extensive popularization of ozone in healthcare.SummaryDespite the small number of specific studies, many recent, results postulate ozone as a promising alternative for the management of IC/BPS given its antioxidant, a...
Source: Current Bladder Dysfunction Reports - October 13, 2023 Category: Urology & Nephrology Source Type: research

Evaluation and Revision of Artificial Urinary Sphincter Failure for Male Stress Urinary Incontinence
AbstractPurpose of ReviewTo examine preoperative diagnostic tools for evaluating artificial urinary sphincter failure and operative techniques for device revision. We focus our discussion of device revision on stepwise approaches for the replacement of individual components versus the replacement of the entire device.Recent FindingsAlthough the AUS has not changed significantly since its inception nearly 50 years ago, there have been a variety of proposed approaches to the assessment and management of failed devices, particularly in how each component is treated at the time of revision surgery.SummaryNeed for revision surg...
Source: Current Bladder Dysfunction Reports - October 6, 2023 Category: Urology & Nephrology Source Type: research

Role of Onabotulinum Toxin-A Injection in the Management of Pain and Sexual Dysfunction in Women with BPS/IC
AbstractPurpose of ReviewIn this review, we aimed to summarize the effects of BoNT-A injections on pain and sexual dysfunction in women with BPS/IC in the light of current literature.Recent FindingsIn recent years, randomized controlled studies have provided evidence for the positive effects of intravesical BoNT-A treatment on pain and quality of life scores in patients with BPS/IC. Trigonal injections have demonstrated similar efficacy and safety to those administered to the bladder body. Furthermore, noninvasive alternatives such as low-energy shock wave plus intravesical instillation, hydrogel-based instillation, and li...
Source: Current Bladder Dysfunction Reports - October 2, 2023 Category: Urology & Nephrology Source Type: research

Bladder Stones in Pediatric Patients with Bladder Dysfunction: a Review of Pathophysiology and Management
AbstractPurpose of ReviewBladder stones are a prevalent problem in children with neurogenic bladder that impact quality of life and subject patients to multiple procedures. The physiology of bladder dysfunction as well as medical interventions employed to efficiently empty the bladder and lower bladder pressures contribute to the formation of stones. In this paper, we aim to review the literature concerning bladder stone pathophysiology, prevention, surveillance, and surgical management for pediatric patients suffering from neurogenic bladder.Recent FindingsHistorical data has provided the basis of our understanding of pat...
Source: Current Bladder Dysfunction Reports - September 30, 2023 Category: Urology & Nephrology Source Type: research

The Role of Viral Infection in the Pathogenesis of Interstitial Cystitis/Bladder Pain Syndrome
AbstractPurpose of ReviewThe pathogenesis of interstitial cystitis/bladder pain syndrome (IC/BPS) is still unclear. The diagnosis of IC/BPS is made after ruling out bacterial cystitis. However, viral infection in the bladder might be a pathogenic factor for IC/BPS. The purpose of this review is to demonstrate the association between viral infection and IC/BPS.Recent FindingsThe presence of urinary tract viruses in patients with IC/BPS has been sporadically investigated since the 1970s. Early studies used viral culture to investigate urine and bladder tissue samples from patients with IC/BPS, but viruses were rarely detecte...
Source: Current Bladder Dysfunction Reports - September 30, 2023 Category: Urology & Nephrology Source Type: research

Outcomes of Current Bladder Outlet Techniques for Neurogenic Bladder Dysfunction
This article evaluates the literature published from 2016 to 2023 regarding bladder outlet techniques for neurogenic bladder dysfunction in children.Recent FindingsContinence rates following open bladder neck reconstruction remain highly variable, ranging from 17 to 96% in recent series. Augmentation cystoplasty at the time of bladder neck reconstruction appears to improve both postoperative continence and bladder compliance in longer-term follow-up, with a large percentage of children undergoing isolated bladder neck procedures progressing to augmentation cystoplasty within a few years of reconstruction. Artificial urinar...
Source: Current Bladder Dysfunction Reports - September 14, 2023 Category: Urology & Nephrology Source Type: research

Management of Elevated Post-Void Residual Volume
AbstractPurpose of ReviewElevated post-void residual volume (ePVR) also known as chronic urinary retention (CUR) is a chronic condition of incomplete bladder emptying in the absence of pain or discomfort. ePVR may be secondary to several etiologies: obstructive, neurogenic, vascular, myogenic, or a combination of these. It can be further divided into symptomatic (e.g., accompanied with lower urinary tract symptoms), or asymptomatic. In this article, we sought to review the literature regarding definition of ePVR, etiology, clinical significance, initial assessment, treatment, and follow-up.Recent FindingsWe performed a sys...
Source: Current Bladder Dysfunction Reports - September 9, 2023 Category: Urology & Nephrology Source Type: research