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Moderate and Severe Traumatic Brain Injury
This article reviews TBI in neurocritical care, hence focusing on moderate and severe TBI, and includes an up-to-date review of the many variables to be considered in clinical care. RECENT FINDINGS With advances in medicine and biotechnology, understanding of the impact of TBI has substantially elucidated the distinction between primary and secondary brain injury. Consequently, care of TBI is evolving, with intervention-based modalities targeting multiple physiologic variables. Multimodality monitoring to assess intracranial pressure, cerebral oxygenation, cerebral metabolism, cerebral blood flow, and autoregulation...
Source: CONTINUUM: Lifelong Learning in Neurology - October 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Intracerebral Hemorrhage
This article summarizes the basic pathophysiology, classification, and management of ICH and discusses the available evidence on therapy for hematoma, hematoma expansion, and perihematomal edema. RECENT FINDINGS Current available data on potential therapeutic options for ICH are promising, although none of the trials have shown improvement in mortality rate. The literature available on reversal of anticoagulation and antiplatelet agents after an ICH and resumption of these medications is also increasing. SUMMARY ICH continues to have high morbidity and mortality. Advances in therapeutic options to target seco...
Source: CONTINUUM: Lifelong Learning in Neurology - October 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Subarachnoid Hemorrhage
This article uses a case-based approach to guide readers through the fundamental epidemiology and pathogenesis of SAH, the approach to diagnosis and management, the results of clinical trials and evidence to date, prognostic considerations, controversies, recent developments, and future directions in SAH. RECENT FINDINGS Historically, management of SAH focused on prevention and treatment of subsequent cerebral vasospasm, which was thought to be the primary cause of delayed cerebral ischemia. Clinical and translational studies over the past decade, including several therapeutic phase 3 randomized clinical trials, sug...
Source: CONTINUUM: Lifelong Learning in Neurology - October 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Management of Cerebral Edema, Brain Compression, and Intracranial Pressure
This article reviews the pathophysiology and management of cerebral edema, brain compression, and elevated intracranial pressure (ICP). It also provides a brief introduction to the concept of the glymphatic system and select cellular contributors to cerebral edema. RECENT FINDINGS Cerebral edema and brain compression should be treated in a tiered approach after the patient demonstrates a symptomatic indication to start treatment. All patients with acute brain injury should be treated with standard measures to optimize intracranial compliance and minimize risk of ICP elevation. When ICP monitors are used, therapies s...
Source: CONTINUUM: Lifelong Learning in Neurology - October 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Critical Conversations
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Source: CONTINUUM: Lifelong Learning in Neurology - October 1, 2021 Category: Neurology Tags: EDITOR’S PREFACE Source Type: research

Contributors
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Source: CONTINUUM: Lifelong Learning in Neurology - October 1, 2021 Category: Neurology Tags: CONTRIBUTORS Source Type: research

Table of Contents
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Source: CONTINUUM: Lifelong Learning in Neurology - October 1, 2021 Category: Neurology Tags: Table of Contents Source Type: research

Issue Overview
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Source: CONTINUUM: Lifelong Learning in Neurology - August 1, 2021 Category: Neurology Tags: ISSUE OVERVIEW Source Type: research

Key Points for Issue
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Source: CONTINUUM: Lifelong Learning in Neurology - August 1, 2021 Category: Neurology Tags: KEY POINTS FOR ISSUE Source Type: research

List of Abbreviations
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Source: CONTINUUM: Lifelong Learning in Neurology - August 1, 2021 Category: Neurology Tags: LIST OF ABBREVIATIONS Source Type: research

Learning Objectives and Core Competencies
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Source: CONTINUUM: Lifelong Learning in Neurology - August 1, 2021 Category: Neurology Tags: LEARNING OBJECTIVES AND CORE COMPETENCIES Source Type: research

Errata
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Source: CONTINUUM: Lifelong Learning in Neurology - August 1, 2021 Category: Neurology Tags: Errata Source Type: research

Postreading Self-Assessment and CME Test—Preferred Responses
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Source: CONTINUUM: Lifelong Learning in Neurology - August 1, 2021 Category: Neurology Tags: SELF-ASSESSMENT AND CME Source Type: research

Postreading Self-Assessment and CME Test
No abstract available (Source: CONTINUUM: Lifelong Learning in Neurology)
Source: CONTINUUM: Lifelong Learning in Neurology - August 1, 2021 Category: Neurology Tags: SELF-ASSESSMENT AND CME Source Type: research

Self-assessment and cme
No abstract available (Source: CONTINUUM: Lifelong Learning in Neurology)
Source: CONTINUUM: Lifelong Learning in Neurology - August 1, 2021 Category: Neurology Tags: SELF-ASSESSMENT AND CME Source Type: research