Mood Disorders
This article highlights the medications frequently used with newly identified mood disorders and the common side effects of these medications. A paradigm shift has moved toward newer treatment modalities, such as the use of ketamine, repetitive transcranial magnetic stimulation, and complementary and alternative medicine. The risks and benefits of such therapies, along with medications, are reviewed in this article. SUMMARY Mood disorders are extraordinarily complex disorders with significant association with many neurologic disorders. Early identification of these mood disorders can prevent significant morbidity an...
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Psychosis
This article reviews the definition of psychotic symptoms and the evaluation and management of psychosis in primary psychiatric and neurologic disorders frequently seen in neurologic practice. RECENT FINDINGS Emerging evidence supports significant connections between psychosis and structural and functional brain changes in both primary psychotic and neurologic disorders. In addition to antidopaminergic activity, the mechanism of new-generation antipsychotics shifts to act on serotonin receptors, which potentially contributes to their benefits in the treatment of negative symptoms of psychosis and a lesser frequency ...
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Cognitive Rehabilitation
This article provides a definition of and introduction to cognitive rehabilitation. It discusses different approaches to cognitive rehabilitation (ie, restorative, compensatory, and metacognitive). It also reviews types of memory impairment and how they can be distinguished to improve treatment design and implementation. RECENT FINDINGS Neural plasticity as a biological substrate for functional changes from cognitive rehabilitation is an exciting new area of research. SUMMARY This article provides a high-level review of cognitive rehabilitation and presents a complex case example. (Source: CONTINUUM: Lifelong...
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Behavioral and Cognitive Aspects of Concussion
PURPOSE OF REVIEW This review provides the reader with an overview of concussion and mild traumatic brain injury (TBI). Key aspects of the pathophysiology, signs, and symptoms, treatment and rehabilitation, and recovery from concussion/mild TBI are reviewed with an emphasis on the variety of factors that may contribute to cognitive concerns following injury. RECENT FINDINGS Concussion remains a clinical diagnosis based on symptoms that occur in the immediate aftermath of an applied force and in the hours, days, and weeks thereafter. Although advances have been made in advanced diagnostics, including neuroimaging...
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Spatial Neglect and Anosognosia After Right Brain Stroke
This article guides neurologists’ assessment of right brain cognitive disorders and describes how to efficiently assemble and direct a treatment team to address spatial neglect and unawareness of deficit. (Source: CONTINUUM: Lifelong Learning in Neurology)
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Upper Limb Apraxia
This article discusses the signs and symptoms of, means of testing for, the pathophysiology of, and possible management of upper limb apraxia. RECENT FINDINGS Upper limb apraxia has four major forms: ideomotor, limb-kinetic, conceptual, and ideational. Although recent findings are included in this article, a full understanding of these disorders, including the means of testing, their possible pathophysiology, and the diseases that may cause these disorders, requires that some older literature is also discussed. SUMMARY This article guides clinicians in testing for and diagnosing the different forms of upper l...
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Executive Dysfunction and the Prefrontal Cortex
This article summarizes the cognitive and behavioral functions of the prefrontal cortex with an emphasis on executive cognitive functions and the clinical consequences associated with executive dysfunction. The clinical manifestations of lesions to the lateral prefrontal, orbitofrontal, medial prefrontal, and frontopolar cortex are reviewed. RECENT FINDINGS Traditional lesion studies have emphasized the role of a brain region in controlling a cognitive function. With advances in neurology, neuropsychology, and neuroimaging, the participation of the prefrontal cortex in large-scale networks has been established with ...
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Memory Dysfunction
This article provides a practical overview of the diagnostic process for patients with memory dysfunction through exploration of the anatomic, physiologic, and psychological aspects of human memory. RECENT FINDINGS As updated methods become available to neurologists, the ability to accurately identify and treat patients with memory disorders evolves. An appreciation of current concepts in the anatomic, physiologic, and psychological aspects of memory, combined with a rational application of everyday tools (such as clinical examination, bedside testing, standardized cognitive screening, and formal neuropsychological ...
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Language and Aphasias
This article reveals how it is possible for a brain composed of 100 billion highly interconnected, lipid-encased, reticular electrochemical devices to support complex functions such as language and how language disorders can be understood as a reflection of degradation of one or more domains of knowledge. RECENT FINDINGS Ongoing research, building on landmark work regarding parallel distributed processing (PDP), provides the basis for understanding cognitive functions as a manifestation of the activity of populations of millions or billions of neurons in various highly interconnected networks. Population encoding ne...
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Clinical Approach to Cognitive and Neurobehavioral Symptoms
This article provides a framework for the approach to patients with cognitive or neurobehavioral concerns. RECENT FINDINGS Recent advances in structural neuroimaging, functional neuroimaging, and disease biomarkers have greatly expanded knowledge of brain-behavior relationships, neural networks and functional connectivity, and pathophysiologic processes leading to cognitive and neurobehavioral disorders. However, any one of these studies is subject to misinterpretation if not applied in the appropriate clinical context. SUMMARY A systematic approach to the history and examination in patients with cognitive an...
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Sentences for Good Behavior
No abstract available (Source: CONTINUUM: Lifelong Learning in Neurology)
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: EDITOR’S PREFACE Source Type: research

Contributors
No abstract available (Source: CONTINUUM: Lifelong Learning in Neurology)
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: CONTRIBUTORS Source Type: research

Table of Contents
No abstract available (Source: CONTINUUM: Lifelong Learning in Neurology)
Source: CONTINUUM: Lifelong Learning in Neurology - December 1, 2021 Category: Neurology Tags: Table of Contents Source Type: research

Issue Overview
No abstract available (Source: CONTINUUM: Lifelong Learning in Neurology)
Source: CONTINUUM: Lifelong Learning in Neurology - October 1, 2021 Category: Neurology Tags: ISSUE OVERVIEW Source Type: research

Key Points for Issue
No abstract available (Source: CONTINUUM: Lifelong Learning in Neurology)
Source: CONTINUUM: Lifelong Learning in Neurology - October 1, 2021 Category: Neurology Tags: KEY POINTS FOR ISSUE Source Type: research