Fluoride Binding to Dental Biofilm Bacteria: Synergistic Effect with Calcium Questioned
It has been suggested that fluoride binding to dental biofilm is enhanced when more bacterial calcium binding sites are available. However, this was only observed at high calcium and fluoride concentrations (i.e., when CaF2 precipitation may have occurred). We assessed fluoride binding toStreptococcus mutans pellets treated with calcium and fluoride at concentrations allowing CaF2 precipitation or not. Increasing calcium concentration resulted in a linear increase (p #x3c; 0.01) in fluoride concentration only in the pellets in which CaF2 precipitated. The results suggest that CaF2 precipitation, rather than bacterially bou...
Source: Caries Research - June 6, 2018 Category: Dentistry Source Type: research
Fluoride Penetration and Clearance Are Higher in Exopolysaccharide-Containing Bacterial Pellets
Extracellular polysaccharides (EPS) could increase the penetration of fluoride through dental biofilm, reducing its cariogenicity. We measured the concentration of fluoride in EPS-containing (EPS+) or not-containing (EPS–)Streptococcus mutans bacterial pellets resembling test biofilms, before and up to 60 min after a 0.05% NaF rinse in situ. Fluoride penetration and clearance were higher in EPS+ bacterial pellets. The data suggest that EPS enhances fluoride penetration, but also accelerates fluoride clearance from dental biofilms.Caries Res 2019;53:16 –23 (Source: Caries Research)
Source: Caries Research - June 6, 2018 Category: Dentistry Source Type: research
The Effect of Silver Diamine Fluoride in Preventing Caries in the Primary Dentition: A Systematic Review and Meta-Analysis
Conclusion: When applied to caries lesions in primary teeth, SDF compared to no treatment, placebo or FV appears to effectively prevent dental caries in the entire dentition. However, trials specifically designed to assess this outcome are needed.Caries Res 2019;53:24 –32 (Source: Caries Research)
Source: Caries Research - June 6, 2018 Category: Dentistry Source Type: research
Validation of a Real-Time ISE Methodology to Quantify the Influence of Inhibitors of Demineralization Kinetics in vitro Using a Hydroxyapatite Model System
In conclusion, real-time Ca2+ ISE systems can be used to measure the cariostatic efficacies of demineralization inhibitors.Caries Res 2018;52:598 –603 (Source: Caries Research)
Source: Caries Research - May 29, 2018 Category: Dentistry Source Type: research
In situ Effect of Arginine-Containing Dentifrice on Plaque Composition and on Enamel Demineralization under Distinct Cariogenic Conditions
This study aimed to assess the effect of AFD on enamel demineralization and on the microbial and biochemical compositions of biofilm formed under different frequencies of sucrose exposure. It consisted of an in situ split-mouth design, where 12 adult volunteers who used FD for at least 2 months prior to the beginning of this study wore acrylic palatal appliances containing 4 bovine enamel specimens (1 pair at each side of the appliance) during 2 phases of 14 days each. FD slurry (3 ×/day) and 20% sucrose solution (4× and 8×/day) were dripped on the specimens during the first experimental phase. The same volunteers then ...
Source: Caries Research - May 4, 2018 Category: Dentistry Source Type: research
