Fluoride Dentifrice Overcomes the Lower Resistance of Fluorotic Enamel to Demineralization
We evaluated if the low resistance of fluorotic enamel to demineralization could be overcome by fluoride dentifrice (FD) treatment. Paired enamel slabs of sound and fluorotic enamel (n = 20/group) from human teeth presenting Thylstrup and Fejerskov index (TF) scores from 0 to 4 were obtained. Half of the anatomic surface of the enamel slabs was isolated and used as a control (baseline) regarding enamel mineralization and fluoride concentration. The slabs were submitted to a pH-cycling model simulating a high cariogenic challenge, and 2 ×/day they were treated with placebo dentifrice (PD) or FD (1,100 µg F/g, as NaF). Aft...
Source: Caries Research - May 21, 2019 Category: Dentistry Source Type: research

Effect of Different Liners on Pulpal Outcome after Partial Caries Removal: A Preliminary 12 Months Randomised Controlled Trial
Conclusion: Partial caries excavation has a high success rate to treat deep carious lesions in permanent teeth after 12 months of follow-up, indicating that the retention of carious dentin does not interfere with pulp vitality or restoration survival. Also, the success of the treatment is independent of the lining material used over the demineralized dentin.Caries Res (Source: Caries Research)
Source: Caries Research - May 17, 2019 Category: Dentistry Source Type: research

Acquired Enamel Pellicle Modification with Casein and Mucin in Different Concentrations and its Impact on Initial Dental Erosion
Casein and mucin have been shown to improve the erosion-protective properties of the pellicle when applied in combination. The aim of this in vitro study was to optimize the concentrations of these 2 proteins to achieve a maximum protective effect. For the 2 parts of this study, we prepared a total of 195 human enamel specimens and randomly assigned them to 13 groups, corresponding to 11 different casein-mucin concentration-combinations tested and 2 negative control groups (humid chamber). They underwent 5 cycles, consisting of pellicle formation from human whole saliva (2 h, 30 °C), modification of the pellicle with case...
Source: Caries Research - May 14, 2019 Category: Dentistry Source Type: research

Protective Effect of 4% Titanium Tetrafluoride Varnish on Dentin Demineralization Using a Microcosm Biofilm Model
This study evaluated the effect of titanium tetrafluoride (TiF4) varnish on the development of dentin carious lesions. Bovine root dentin samples were treated for 6 h with: (A) 4% TiF4 varnish (2.45% F); (B) 5.42% sodium fluoride (NaF) varnish (2.45% F); (C) 2% chlorhexidine (CHX) gel – positive control; (D) placebo varnish; or (E) untreated – negative control (n = 4 × biological triplicate,n = 12). Treated dentin samples were exposed to human saliva mixed with McBain saliva (1:50) for the first 8 h in 24-well plates. Thereafter, the medium was removed, and McBain saliva containing 0.2% sucrose was applied for 16 h. F...
Source: Caries Research - May 14, 2019 Category: Dentistry Source Type: research

Erratum
Caries Res (Source: Caries Research)
Source: Caries Research - May 11, 2019 Category: Dentistry Source Type: research

Oral and Systemic Effects of Xylitol Consumption
Recent results of randomized trials testing the efficacy of xylitol in caries prevention have been conflicting. This narrative review reveals the sources of discrepancy. The following databases were searched for the terms “xylitol” or “artificial sweeteners” restricted to the English language: PubMed, Web of Science, Evidenced-Based Medicine, Scopus, and the Cochrane database. In a separate search, the terms “dental caries” or “cariogenicity” or “glucosyltransferase” or “low glycemic” or “lo w insulinemic” or “dysbiosis” or “gut microbiome” were used and then combined. In section I, find...
Source: Caries Research - May 6, 2019 Category: Dentistry Source Type: research

Erratum
Caries Res (Source: Caries Research)
Source: Caries Research - May 5, 2019 Category: Dentistry Source Type: research

Critical Appraisal of Oral Pre- and Probiotics for Caries Prevention and Care
In recent years, the concept of preventing caries-related microbial dysbiosis by enhancing the growth and survival of health-associated oral microbiota has emerged. In this article, the current evidence for the role of oral pre- and probiotics in caries prevention and caries management is discussed. Prebiotics are defined as “substrates that are selectively utilized by host microorganisms conferring a health benefit.” With regard to caries, this would include alkali-generating substances such as urea and arginine, which are metabolized by some oral bacteria, resulting in ammonia production and increase in pH. While the...
Source: Caries Research - April 15, 2019 Category: Dentistry Source Type: research

On the Variable Clinical Presentation of Molar-Incisor Hypomineralization
In this report, we provide a rationale to explain the variation seen in the clinical presentation of MIH, which can affect just one molar out of the four or just a portion of a particular molar.Caries Res (Source: Caries Research)
Source: Caries Research - April 3, 2019 Category: Dentistry Source Type: research

Association of Enamel Caries Lesions with Oral Hygiene and DMFT among Adults
In conclusion, the prevalence of enamel caries lesions is high among the Finnish adult population. The results of this study suggest that in addition to tooth brushing frequency, the presence of visible plaque seems to be critical when evaluating the association between tooth brushing and enamel caries.Caries Res (Source: Caries Research)
Source: Caries Research - March 31, 2019 Category: Dentistry Source Type: research

Estimating a Dynamic Effect of Soda Intake on Pediatric Dental Caries Using Targeted Maximum Likelihood Estimation Method
In conclusion, consistent soda intake during the early childhood led to one additional caries tooth surface. The study highlights utility of TMLE in pe diatric caries research as it can handle modeling challenges associated with longitudinal data.Caries Res (Source: Caries Research)
Source: Caries Research - March 20, 2019 Category: Dentistry Source Type: research

Introducing a Specific Term to Present Caries Experience in Populations with Low Caries Prevalence: Specific Affected Caries Index (SaC)
Up to now, indices like the mean dmft/DMFT and the SiC (Significant Caries Index) have been used to depict caries experience in populations with high prevalence. With the caries decline, particularly for populations with low caries levels, these indices reach their statistical limits. This paper aims to introduce a specific term, the Specific affected Caries Index (SaC) for the risk groups in populations with low caries prevalence and to illustrate its use based on the consecutive German National Oral Health Survey (GNOHS) in children. In groups with a caries prevalence less than one-third of the population, many caries-fr...
Source: Caries Research - March 14, 2019 Category: Dentistry Source Type: research

Cup-Shaped Tooth Wear Defects: More than Erosive Challenges?
Conclusion: The study showed that a cup can arise fully in enamel and that mechanical loading in addition to erosive challenges are required.Caries Res (Source: Caries Research)
Source: Caries Research - March 7, 2019 Category: Dentistry Source Type: research

Assessment of the Silver Penetration and Distribution in Carious Lesions of Deciduous Teeth Treated with Silver Diamine Fluoride
The aim of this study was to determine the effects of 38% silver diamine fluoride (SDF) on carious lesions of human deciduous teeth. Ten extracted deciduous incisors with caries were collected and treated with SDF. After the treatment, the teeth were sectioned through the center of the carious lesion. The extent of sliver precipitation was examined using quantitative backscattered electron scanning electron microscopy (qBSE-SEM), energy-dispersive X-ray spectroscopy (EDX), and micro-computed tomography (micro-CT). The qBSE-SEM images revealed that the silver particles could penetrate through the pellicle complex, along wit...
Source: Caries Research - February 26, 2019 Category: Dentistry Source Type: research

Evaluation of Restorative Materials Containing Preventive Additives in a Secondary Caries Model in vitro
The incorporation of antibacterial agents into dental restorative materials is a promising strategy for secondary caries prevention. Previously, Carolacton affectedStreptococcus mutans biofilm formation on composite materials in vitro. The present study evaluated secondary caries formation adjacent to Carolacton-containing composites and conventional restorative materials using an artificial biofilm model. Standardized cavities were prepared in bovine dentin-enamel samples (n = 175) and restored with various dental materials (Tetric EvoCeram [T], GrandioSo composite without [G] and with Carolacton [GC], Grandio Flow withou...
Source: Caries Research - February 20, 2019 Category: Dentistry Source Type: research