68th ORCA Congress
Caries Res (Source: Caries Research)
Source: Caries Research - July 5, 2021 Category: Dentistry Source Type: research
Routine Data Analyses for Estimating the Caries Treatment Experience of Children
(Source: Caries Research)
Source: Caries Research - June 29, 2021 Category: Dentistry Source Type: research
Rinsing with statherin-derived peptide alters the proteome of the acquired enamel pellicle
(Source: Caries Research)
Source: Caries Research - June 24, 2021 Category: Dentistry Source Type: research
Detection Methods for Early Caries Diagnosis: A Systematic Review and Meta-Analysis
The aim was to appraise the evidence on the performance of various means for the detection of incipient caries in vivo. Five databases of published and unpublished research were searched for studies from January 2000 to October 2019. Search terms included “early caries” and “caries detection.” Inclusion criteria involved diagnostic test accuracy studies for early caries detection in permanent and primary teeth. A risk-of-bias assessment was performed using the QUADAS-2 tool. We performed the study selection, data extraction, and risk-of-bias assessment in duplicate. The review protocol was a priori registered in th...
Source: Caries Research - June 15, 2021 Category: Dentistry Source Type: research
Cariogenic Potential of Human and Bovine Milk on Enamel Demineralization
The higher cariogenicity of human milk when compared with bovine milk is still a debatable subject. Therefore, we evaluated the effect of human or bovine milk exposure on biofilm composition and enamel demineralization using a validated cariogenic biofilm model.Streptococcus mutans UA159 biofilms (n = 8) were grown on human saliva-coated bovine enamel slabs of known surface hardness. The biofilms were exposed 8 ×/day to 0.9% NaCl (negative control), human milk, bovine milk, 7.0% lactose (active human milk control), 4.5% lactose (active bovine milk control), or 10% sucrose (positive control). The culture medium was changed...
Source: Caries Research - June 15, 2021 Category: Dentistry Source Type: research
Dental Health Inequalities among Indigenous Populations: A Systematic Review and Meta-Analysis
The aim of this systematic review and meta-analysis was to document the disparity in dental caries experiences among indigenous and nonindigenous populations globally by measuring dental caries prevalence and severity. An electronic database (MEDLINE) was initially searched using relevant keywords. This was followed by use of the search string in the following electronic databases: Scopus, EBSCOhost, Cochrane, and Open Grey. Two independent reviewers conducted the study search and screening, quality assessment, and data extraction, which was facilitated using JBI SUMARI software. The primary outcome was the decayed missing...
Source: Caries Research - June 9, 2021 Category: Dentistry Source Type: research
Glass Ionomer Sealants Can Prevent Dental Caries but Cannot Prevent Posteruptive Breakdown on Molars Affected by Molar Incisor Hypomineralization: One-Year Results of a Randomized Clinical Trial
To evaluate the preventive effect of glass ionomer cement (GIC) against dental caries and posteruptive breakdown (PEB) on molars affected by molar incisor hypomineralization (MIH). In this randomized clinical trial, 77 children aged 5 –9 years with at least 1 MIH-affected molar and without PEB or dentin caries lesions (n = 228) were included and randomly allocated to one of the following groups: (1) MIH-affected molars that remained unsealed and (2) MIH-affected molars that received GIC sealants. Dental caries and PEB were clinically evaluated after 6 and 12 months. Associations between dental caries and PEB with indepen...
Source: Caries Research - June 9, 2021 Category: Dentistry Source Type: research
< b > < i > Streptococcus salivarius < /i > < /b > Isolates of Varying Acid Tolerance Exhibit F < sub > 1 < /sub > F < sub > 0 < /sub > -ATPase Conservation
Genes encoding the subunits of the membrane-bound F1F0-ATPase (responsible for exporting protons from the cytoplasm and contributing to acid tolerance) were sequenced for 24 non-mutans streptococci isolated from carious lesions. Isolates, mostlyStreptococcus salivarius, displayed a continuum of acid tolerance thresholds ranging from pH 4.55 to 3.39, but amino acid alignments of F1F0-ATPase subunits revealed few non-synonymous substitutions and these were unrelated to acid tolerance. Thus, the F1F0-ATPase is highly-conserved amongS. salivarius isolates despite varying acid tolerance thresholds, supporting the contention tha...
Source: Caries Research - June 7, 2021 Category: Dentistry Source Type: research
Biomarkers for the Assessment of Exposure to Fluoride in Adults
In conclusion, this study has indicated the usefulness of 24-h UFE as well as F concentration in plasma, fasting whole saliva and hair as biomarkers of contemporary or sub-chronic F exposure in groups of adults. However, they do not appear to have the necessary sensitivity to predict F exposure in individuals.Caries Res (Source: Caries Research)
Source: Caries Research - June 1, 2021 Category: Dentistry Source Type: research
Green Tea-Derived Epigallocatechin Gallate Inhibits Acid Production and Promotes the Aggregation of < b > < i > Streptococcus mutans < /i > < /b > and Non-Mutans Streptococci
In this study, the antimicrobial properties of EGCG were evaluated by examining its bactericidal activity, its inhibitory effects against bacterial growth, acid production, acidic end-product formation, and sugar uptake (phosphoenolpyruvate-dependent phosphotransferase system, PEP-PTS activity), and its effects on bacterial aggregation, using monocultured planktonic cells ofStreptococcus mutans and non-mutans streptococci. CoincubatingS. mutans with EGCG (1 mg/mL) for 4 h had no bactericidal effects, while it decreased the growth and acid production ofS. mutans by inhibiting the activity of the PEP-PTS. EGCG (2 mg/mL) caus...
Source: Caries Research - May 19, 2021 Category: Dentistry Source Type: research
The Effect of Solutions Containing Extracts of < b > < i > Vochysia tucanorum < /i > < /b > Mart., < b > < i > Myrcia bella < /i > < /b > Cambess., < b > < i > Matricaria chamomilla < /i > < /b > L. and < b > < i > Malva sylvestris < /i > < /b > L. on Cariogenic Bacterial Species and Enamel Caries Development
This study evaluated the effect of experimental solutions containing plant extracts on bacterial species and enamel caries prevention. Microcosm biofilm was produced from human saliva mixed with McBain saliva (0.2% sucrose) on bovine enamel for 5 days (3 days under anaerobiosis and 2 days under aerobiosis) at 37 °C. From the 2nd day, the following treatments were applied (1 × 60 s/day):Vochysia tucanorum (10 mg/mL);Myrcia bella (5 mg/mL);Matricaria chamomilla (80 mg/mL);Malva sylvestris, fluoride, and xylitol (Malvatricin Plus ®); 0.12% chlorhexidine (CHX, PerioGard®); and PBS (negative control). The medium pH was meas...
Source: Caries Research - May 17, 2021 Category: Dentistry Source Type: research
Taxes to Unhealthy Food and Beverages and Oral Health in Mexico: An Observational Study
In January 2014, taxes on sugar-sweetened beverages and nonessential energy-dense food were implemented in Mexico to discourage the consumption of these products. Published evaluations have shown reductions in purchases of taxed food and beverages associated with the implementation of this fiscal policy. Although there are some studies on the impact on health based on simulation studies, no evaluations with empirical data on changes in oral health have been published. We used administrative records and data from an epidemiological surveillance system to estimate changes in (1) outpatient visits related to dental caries; (2...
Source: Caries Research - April 14, 2021 Category: Dentistry Source Type: research
JNK Signaling Pathway Mediates Fluoride-Induced Upregulation of CK1 α during Enamel Formation
This study aimed to investigate the effects of fluoride on CK1α expression and to assess the regulation of molecular signaling involving fluoride a nd CK1α during enamel development. Kunming mice were randomly divided into the control and F groups with induced clinical features of fluorosis. The F group mice, including mothers and newborns, were treated with 50 ppm fluoridated water. Immunohistochemical staining of the sections of the embryoni c mandible regions was performed at the bell stage. Protein expression and signaling pathways in a mouse-derived ameloblast-like cell line (LS8) exposed to fluoride or a Jun N-term...
Source: Caries Research - April 7, 2021 Category: Dentistry Source Type: research
The Impact of Early Childhood Factors on Dental Caries Incidence in First Permanent Molars: A 7-Year Follow-Up Study
In conclusion, individual and cont extual determinants showed an important role in the incidence of caries in first permanent molars.Caries Res (Source: Caries Research)
Source: Caries Research - March 31, 2021 Category: Dentistry Source Type: research
Fluoride Binding to < b > < i > Streptococcus mutans < /i > < /b > Pellets Rich in Extracellular Polysaccharides
In conclusion, the data suggest that a matrix of dental biofilm rich in EPS does not affect fluoride retention in the biofilm.Caries Res (Source: Caries Research)
Source: Caries Research - March 29, 2021 Category: Dentistry Source Type: research
