The role of oral nitrate-reducing bacteria in the prevention of caries: A review related to caries and nitrate metabolism
Circulating nitrate is actively absorbed by salivary glands and secreted into the oral cavity, where it is reduced to nitrite by oral nitrate-reducing bacteria. This process has previously been considered harmful because nitrate and nitrite can promote the formation of potentially carcinogenic N-nitrosamines. However, recent studies have shown that nitrate may have other physiological functions, and it can serve as a precursor for the systemic production of nitric oxide and perform nitric oxide (NO)-like functions, such as promoting vasodilation, regulating metabolic diseases, alleviating senescence, and protecting the dig...
Source: Caries Research - January 17, 2023 Category: Dentistry Source Type: research
Dentine mineral changes induced by polyalkenoate cements after different selective caries removal techniques: An in vitro study
This study aimed at evaluating the mineral variation induced by polyalkenoate cements in residual dentine after different caries removal methods. Ten extracted sound molars were selected, and five cavities were prepared on the occlusal surface of each specimen. Carious lesions were generated using a microbial protocol, while the caries removal was performed using bur, hand excavator or two papain-based chemo-mechanical agents. One cavity was left unexcavated in each tooth. Cavities were restored using a zinc polycarboxylate cement (ZPC; n=25) or a glass ionomer was used (GIC; n=25). Subsequently, the specimens were stored ...
Source: Caries Research - January 14, 2023 Category: Dentistry Source Type: research
A bibliometric analysis of studies on root caries
This study aimed to review the current state of the root caries field, explore the current hot topic, and anticipate future research frontiers. The Web of Science Core Collections (WoSCC) was searched to acquire publications that were relevant to root caries from 1992 to 2021. After retrieval and manual screening, the co-occurrence and co-operation analysis of keywords and countries/institutions/authors were performed through Citespace and VOSviewer based on two periods (1992 –2006 and 2007–2021). From 1992 to 2021, 451 unique publications were selected. The USA, which has been the center of international cooperation, ...
Source: Caries Research - January 12, 2023 Category: Dentistry Source Type: research
Solutions containing a statherin-derived peptide reduce enamel erosion in vitro
The effect of solutions containing a statherin-derived peptide (Stn15pSpS) on the protection against enamel erosion in vitro was evaluated. Bovine enamel specimens were divided into 4 groups (n = 15/group): 1) Deionized water (negative control), 2) Elmex Erosion Protection ™ (positive control), 3) 1.88 × 10-5 M Stn15pSpS and 4) 3.76 × 10-5 M Stn15pSpS. The solutions were applied on the specimens for 1 min. Stimulated saliva was collected from 3 donors and used to form a 2-h acquired pellicle on the specimens. Then, the specimens were submitted to an erosive pH-cyc ling protocol 4 times/day, for 7 days (0.01 M HCl pH 2....
Source: Caries Research - January 11, 2023 Category: Dentistry Source Type: research
Factors Related to Early Childhood Caries in 17- to 23-Month-Old Children in Aichi Prefecture, Japan: A Cross-Sectional Study
Dental caries is the most prevalent of chronic oral conditions. We investigated child and parental factors associated with early childhood caries (ECC) in 17- to 23-month-old children in Aichi Prefecture, Japan. Of the 61,714 children who underwent a health examination at 18 months of age, 54,206 (27,860 males, 26,346 females) were included in the analysis. The parents of the children completed a self-administered questionnaire comprising items related to the child ’s eating habits and lifestyle and the parent’s lifestyle and childcare factors. Logistic regression analyses were performed using ECC as the dependent vari...
Source: Caries Research - January 10, 2023 Category: Dentistry Source Type: research
The 20-year trends in caries and associated determinants among adults in “post-Soviet” Lithuania: repeated cross-sectional studies
Conclusion. An improvement in dental health during the 20-year period, mainly related to reduction in untreated caries and missing teeth, was observed in adults and early elderly. However, early elderly still had high numbers of missing teeth. The decrease in total caries experience during the 20 years was significant only in adults. Our findings support an urgent need to design and implement national oral health promotion and prevention programs with increased focus on oral self-care and fluoridated toothpaste use. (Source: Caries Research)
Source: Caries Research - January 10, 2023 Category: Dentistry Source Type: research
Association of locus Xq26.1 – 27.3 with Erosive Tooth Wear Phenotypes in a Group of Adolescents
Erosive tooth wear is a multifactorial condition of an increasing prevalence. There is a need for discovering individual genetic predisposition for the development of this condition. Considering that the chromosome X locus was shown to be associated with dental caries, the aim of the present study was to look for the association between this locus and erosive tooth wear when dietary habits are considered as a co-factor. Saliva samples, erosive wear experience data, and dietary information from 16-18 year-old dental patients (n=705) were used. Genotyping analyses were performed, and thereafter, analyses considering diet and...
Source: Caries Research - January 10, 2023 Category: Dentistry Source Type: research
