Cardiovascular and Hematological Agents in Medicinal Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Evaluation of Enhanced Cytotoxicity Effect of Repurposed Drug Simvastatin/ Thymoquinone Combination against Breast Cancer Cell Line
CONCLUSION: It was concluded that the combined effect of simvastatin and thymoquinone stimulates apoptosis in breast cancer cells.PMID:37907488 | DOI:10.2174/0118715257259037231012182741 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - November 1, 2023 Category: Cardiology Authors: Pallavi Kumari Shweta Dang Source Type: research

Cardioprotective Role of Tinospora cordifolia against Trimethylamine-NOxide and Glucose Induced Stress in Rat Cardiomyocytes
CONCLUSION: Conclusively, our study has reported that the Indian medicinal plant Tinospora cordifolia has the ability to treat diabetic cardiomyopathy. Our study can open up a new herbal therapeutic strategy against diabetic cardiomyopathy.PMID:37907489 | DOI:10.2174/0118715257270512231013064533 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - November 1, 2023 Category: Cardiology Authors: Shivani Singhal Vibha Rani Source Type: research

Comparison between the ECG Outcomes of Metoprolol and Bisoprolol
CONCLUSION: In this retrospective cross-sectional study, we have compared the effects of metoprolol and bisoprolol beta blockers on ECG changes. The findings have indicated no difference between metoprolol and bisoprolol groups in terms of all ECG readings, particularly PR/ms, QTC-ms, and ventricular rate. Further studies are required to confirm these findings.PMID:37909439 | DOI:10.2174/0118715257252349231018151957 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - November 1, 2023 Category: Cardiology Authors: Ahmad Abdulrahman Almeman Yousef Obaid Alharbi Abdulaziz Sulaiman Alwahhabi Abdulaziz Abdullah Almutairi Moayad Yousef Alnasr Abdulrahaman Almesnid Source Type: research

Psychosomatic Disorder: The Current Implications and Challenges
Cardiovasc Hematol Agents Med Chem. 2023 Oct 23. doi: 10.2174/0118715257265832231009072953. Online ahead of print.ABSTRACTIn recent years, there has been increasing global concern about the rising prevalence and rapid progression of psychosomatic disorders (PD). This surge can be attributed to irregular biological conditions and the increasingly stressful lifestyles that individuals lead, ultimately resulting in functional impairments of vital organs. PD arises from intricate interactions involving the central nervous, endocrine, and immune systems. Notably, the hypothalamic-pituitaryadrenal (HPA) axis plays an essential r...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - October 24, 2023 Category: Cardiology Authors: Abhimanyu Chauhan Chakresh Kumar Jain Source Type: research

Lipotoxicity, ER Stress, and Cardiovascular Disease: Current Understanding and Future Directions
Cardiovasc Hematol Agents Med Chem. 2023 Oct 6. doi: 10.2174/0118715257262366230928051902. Online ahead of print.ABSTRACTThe endoplasmic reticulum (ER) is a sub-cellular organelle that is responsible for the correct folding of proteins, lipid biosynthesis, calcium storage, and various post-translational modifications. In the disturbance of ER functioning, unfolded or misfolded proteins accumulate inside the ER lumen and initiate downstream signaling called unfolded protein response (UPR). The UPR signaling pathway is involved in lipolysis, triacylglycerol synthesis, lipogenesis, the mevalonate pathway, and low-density lipo...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - October 20, 2023 Category: Cardiology Authors: Smriti Shreya Md Jahangir Alam Anupriya Anupriya Saumya Jaiswal Vibha Rani Buddhi Prakash Jain Source Type: research