Cardiovascular and Hematological Agents in Medicinal Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Subthreshold Doses of Inflammatory Mediators potentiate one another to Elicit Reflex Cardiorespiratory Responses in Anesthetized Rats
CONCLUSION: The present study demonstrates that both bradykinin and histamine potentiate one another in the elicitation of vasosensory reflex responses, and bradykinin is a better potentiator than histamine at the level of perivascular nociceptive afferents in producing reflex CVR changes.PMID:37032504 | DOI:10.2174/1871525721666230407103734 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - April 10, 2023 Category: Cardiology Authors: Ravindran Revand Sanjeev K Singh Madaswamy S Muthu Source Type: research

The negative effects of statin drugs on cardiomyocytes: current review of laboratory and experimental data (mini-review)
Cardiovasc Hematol Agents Med Chem. 2023 Mar 14. doi: 10.2174/1871525721666230314101019. Online ahead of print.ABSTRACTStatin drugs have long been used as a key component of lipid-lowering therapy, which is necessary for the prevention and treatment of atherosclerosis and cardiovascular diseases. Many studies focus on finding and refining new effects of statin drugs. In addition to the main lipid-lowering effect (blocking cholesterol synthesis), statin drugs have a number of pleiotropic effects, including negative effects. The main beneficial effects of statin drugs on the components of the cardiovascular system are: anti-...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - March 15, 2023 Category: Cardiology Authors: Aleksey Michailovich Chaulin Source Type: research