Cardiovascular and Hematological Agents in Medicinal Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A Three-year Retrospective Study Looking at Preventing Hospital Acquired Thrombosis
CONCLUSION: The hospital exceeded the national standard of VTE risk assessment completion on admission (greater than 95%). For almost a quarter of patients with HA-DVT, the dose of thromboprophylaxis prescribed was not appropriate for weight. In five cases of HA-DVT, thromboprophylaxis was omitted with no clear justification. HA-DVT often affects the most clinically vulnerable patients and is associated with a high mortality.PMID:38288832 | DOI:10.2174/0118715257269027231228114930 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - January 30, 2024 Category: Cardiology Authors: Vipin Kammath Anuj Gupta Alexander Bald Gavin Hope Nisheeth Kansal Ahmad Al Samaraee Vish Bhattacharya Source Type: research

Genetic Underpinnings of Pulmonary Fibrosis: An Overview
CONCLUSION: Further comprehensive research is needed to get a blueprint of IPF pathogenesis. The rapidly evolving field of genetic engineering and molecular biology, along with the bioinformatics approach, will possibly explore a new horizon very soon to achieve this goal.PMID:38284708 | DOI:10.2174/0118715257261006231207113809 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - January 29, 2024 Category: Cardiology Authors: Sushweta Mahalanobish Sumit Ghosh Parames C Sil Source Type: research

Can Rosuvastatin Reduce the Risk of Thrombosis in Patients with Hypercholesterolemia with its Effect on Coagulation Factors and Homocysteine Levels?
CONCLUSION: According to the results, it seems that rosuvastatin may be able to reduce the risk of thrombosis in patients by affecting coagulation factors and homocysteine levels.PMID:38279709 | DOI:10.2174/0118715257279903231205110750 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - January 27, 2024 Category: Cardiology Authors: Mostafa Behnam Mohammad Reza Deyhim Parichehreh Yaghmaei Source Type: research

Antihypertensive and ACE-2 Inhibitory Effects of Daphne gnidium in Rats
CONCLUSION: The aqueous extract of Daphne gnidium exhibits antihypertensive activity and induces vasodilatation via the inhibition of Ca2+ entry.PMID:38279710 | DOI:10.2174/0118715257251651231212045407 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - January 27, 2024 Category: Cardiology Authors: Ismail Bouadid Adil Qabouche Mohamed Eddouks Source Type: research

Salivary Biomarkers for Oral Cancer Detection: Insights from Human DNA and RNA Analysis
This article presents a comprehensive review of the current research on salivary biomarkers for oral cancer detection, focusing on insights gained from human DNA and RNA analysis.PMID:38275030 | DOI:10.2174/0118715257269271231201094946 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - January 26, 2024 Category: Cardiology Authors: Archana Navale Atharva Deshpande Source Type: research

Efficacy of Dyslipidemia Control by Combination Therapy with Rosuvastatin 10 Mg and Ezetimibe 10 Mg Compared with Rosuvastatin 20 Mg Monotherapy in Patients with Chronic Coronary Syndromes: A Randomized, Single-blind Controlled Trial
CONCLUSION: Group A's LDL-c reduction effect and target achievement proportion (Rosuvastatin 10mg + Ezetimibe 10 mg) were significantly higher than Group B's (Rosuvastatin 20 mg). Both medication therapies were safe in patients, and the increased dose of monotherapy showed more side effects than the combination therapy.PMID:38275031 | DOI:10.2174/0118715257274373231211060714 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - January 26, 2024 Category: Cardiology Authors: An Viet Tran Bao Lam Thai Tran Nghia Minh Bui Anh Tan To Le Diem Thi Nguyen Son Kim Tran Toan Hoang Ngo Source Type: research

The Role of Gut Microbiota and Associated Compounds in Cardiovascular Health and its Therapeutic Implications
Cardiovasc Hematol Agents Med Chem. 2024 Jan 24. doi: 10.2174/0118715257273506231208045308. Online ahead of print.ABSTRACTIt is possible that gut bacteria may have a beneficial effect on cardiovascular health in humans. It may play a major role in the progression of a variety of cardiovascular diseases, including Heart Failure (HF), Atherosclerosis, Coronary Arterial Disease (CAD), Ischemic Heart Disease (IHD), and Others. Dysbiosis of the gut microbiota, along with its direct and indirect impact on gut health, may induce cardiovascular disorders. Although advanced studies have demonstrated the relationship of various meta...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - January 26, 2024 Category: Cardiology Authors: Lu Liu Guneet Inderjeet Kaur Avinash Kumar Abhinav Kanwal Shailendra Pratap Singh Source Type: research

MicroRNAs Targeting Critical Molecular Pathways in Diabetic Cardiomyopathy Emerging Valuable for Therapy
Cardiovasc Hematol Agents Med Chem. 2024 Jan 24. doi: 10.2174/0118715257265947231129074526. Online ahead of print.ABSTRACTMicroRNAs have emerged as an important regulator of post-transcriptional gene expression studied extensively in many cancers, fetal development, and cardiovascular diseases. Their endogenous nature and easy manipulation have made them potential diagnostic and therapeutic molecules. Diseases with complex pathophysiology such as Diabetic Cardiomyopathy display symptoms at a late stage when the risk of heart failure has become very high. Therefore, the utilization of microRNAs as a tool to study pathophysi...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - January 24, 2024 Category: Cardiology Authors: Priyanka Mathur Sharad Saxena Bhawna Saxena Vibha Rani Source Type: research

Endothelial Cell Aging and Autophagy Dysregulation
This article provides state-of-the-art research on the role of autophagy in endothelial cell aging. Hypothesizing that autophagy dysregulation is associated with early endothelial cell dysfunction and further clinical sequelae, including atherosclerosis formation, leading to various cardiovascular diseases.PMID:38265402 | DOI:10.2174/0118715257275690231129101408 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - January 24, 2024 Category: Cardiology Authors: Basheer Abdullah Marzoog Source Type: research

Incidence Rate of Post Coronary Artery Shunt Complications; Age Dependent!
CONCLUSION: Elderly individuals in the second group who undergo CABG face a greater risk of developing psychosis, arrhythmia, prolonged total and ICU hospitalization, and stroke. The presence of arrhythmia, which is commonly observed in patients aged 63 years and older, significantly affects total hospitalization days. The number of complications is influenced by age, cardiopulmonary bypass (CPB) time, aortic cross-clamp time, ICU hospitalization, and total hospitalization duration.PMID:38265403 | DOI:10.2174/0118715257265595231128070227 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - January 24, 2024 Category: Cardiology Authors: Basheer Abdullah Marzoog Source Type: research

The Genus Anabasis: A Review on Pharmacological and Phytochemical Properties
The objective of the present review was to summarize the phytochemical and pharmacological aspects related to the genus Anabasis. The results of this literature analysis show that among all the species of the Anabasis (A) family, A. aphylla, A. Iranica, A. aretioides, and A. articulata showed antibacterial activity; A. aretioides and A. articulata have antioxidant activity, A. aretioides and A. articulata have antidiabetic activity, A. articulata has cytotoxic activity and A. setifera, A. aretioides, and A. articulata exhibit anti-inflammatory activity. The Anabasis genus contains saponins, and alkaloids, such as anabasine...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - January 23, 2024 Category: Cardiology Authors: Smail Amtaghri Miloudia Slaoui Mohamed Eddouks Source Type: research

Production of Nattokinase from Bacillus Amyloliquifaciens MRS18: A Bacterial Strain Isolated from Fermented Beans
CONCLUSION: From the results of the present study, we concluded that Bacillus amyloliquefaciens isolated from the fermented soya beans produced an NK enzyme that exhibits immense potential to lyse blood clots.PMID:38173058 | DOI:10.2174/0118715257275639231219054353 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - January 4, 2024 Category: Cardiology Authors: Simran B Coutinho Rutuja R Shirodkar Anju K A Vijayaganapathi A Mohanasrinivasan Vaithilingam Subathra Devi C Source Type: research