Autophagy Behavior Under Local Hypothermia in Myocardiocytes Injury
Cardiovasc Hematol Agents Med Chem. 2023 Aug 3. doi: 10.2174/1871525721666230803102554. Online ahead of print.ABSTRACTHypothermia and autophagy are critical regulators of cell homeostasis by regulating intra and intercellular cell communication. Myocardiocyte cryotherapy poses multiple cellular and subcellular effects on the injured cell, including upregulation of autophagy. Autophagy plays a crucial role in modifying cell metabolism by regulating downregulation, reducing reactive oxygen species production, and improving the natural cellular antioxidant defense system. Reduction of reactive oxygen species production and im...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - August 3, 2023 Category: Cardiology Authors: Basheer Abdullah Marzoog Source Type: research