An Insight into Emerging Phytocompounds for Glioblastoma Multiforme Therapy
Cardiovasc Hematol Agents Med Chem. 2023 Nov 10. doi: 10.2174/0118715257262003231031171910. Online ahead of print.ABSTRACTDespite intense research in the field of glioblastoma multiforme (GBM) therapeutics, the resistance against approved therapy remains an issue of concern. The resistance against the therapy is widely reported due to factors like clonal selection, involvement of multiple developmental pathways, and majorly defective mismatch repair (MMR) mediated by O6- methylguanine DNA methyltransferase (MGMT). Phytotherapy is one of the most effective alternatives to overcome resistance. It involves plant-based compoun...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - November 14, 2023 Category: Cardiology Authors: Vijeta Prakash Reema Gabrani Source Type: research