Mitochondria and cancer
(Source: Cancer and Metabolism)
Source: Cancer and Metabolism - June 10, 2014 Category: Cancer & Oncology Source Type: research
Separation of metabolic supply and demand: aerobic glycolysis as a normal physiological response to fluctuating energetic demands in the membrane
Conclusions
Our results show that glycolytic metabolism serves a critical physiological function under normoxic conditions by responding to rapid energetic demand, mainly from membrane transport activities, even in the presence of oxygen. This supports a new model for glucose metabolism in which glycolysis and oxidative phosphorylation supply different types of energy demand. Cells use efficient but slow-responding aerobic metabolism to meet baseline, steady energy demand and glycolytic metabolism, which is inefficient but can rapidly increase adenosine triphosphate (ATP) production, to meet short-tim...
Source: Cancer and Metabolism - June 5, 2014 Category: Cancer & Oncology Source Type: research
The interaction of botanicals and AMPK signaling in the inhibition of castrate-resistant prostate cancer
(Source: Cancer and Metabolism)
Source: Cancer and Metabolism - May 28, 2014 Category: Cancer & Oncology Source Type: research
Glycine decarboxylase is a target for transcriptional repressor Snail
(Source: Cancer and Metabolism)
Source: Cancer and Metabolism - May 28, 2014 Category: Cancer & Oncology Source Type: research
The NADP+-dependent IDH1 mutation and its relevance for glioblastoma patient survival
(Source: Cancer and Metabolism)
Source: Cancer and Metabolism - May 28, 2014 Category: Cancer & Oncology Source Type: research
Pancreatic cancers depend on a non-canonical glutamine metabolism pathway
(Source: Cancer and Metabolism)
Source: Cancer and Metabolism - May 28, 2014 Category: Cancer & Oncology Source Type: research
The power of natural phenolic compounds: caffeic acid is able to enhance the retinoid-induced differentiation of tumor cells
(Source: Cancer and Metabolism)
Source: Cancer and Metabolism - May 28, 2014 Category: Cancer & Oncology Source Type: research
Pioglitazone and thyroid cancer risk in patients with type 2 diabetes
(Source: Cancer and Metabolism)
Source: Cancer and Metabolism - May 28, 2014 Category: Cancer & Oncology Source Type: research
The Regulation of TIGAR
(Source: Cancer and Metabolism)
Source: Cancer and Metabolism - May 28, 2014 Category: Cancer & Oncology Source Type: research
Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate and promotes histone methylation
(Source: Cancer and Metabolism)
Source: Cancer and Metabolism - May 28, 2014 Category: Cancer & Oncology Source Type: research
What cancer is teaching us about cellular metabolism
(Source: Cancer and Metabolism)
Source: Cancer and Metabolism - May 28, 2014 Category: Cancer & Oncology Source Type: research
Effects of biguanides on oxidative phosphorylation
(Source: Cancer and Metabolism)
Source: Cancer and Metabolism - May 28, 2014 Category: Cancer & Oncology Source Type: research
Quantification of NADPH balance during adipogenesis
(Source: Cancer and Metabolism)
Source: Cancer and Metabolism - May 28, 2014 Category: Cancer & Oncology Source Type: research
