Investigation of neomycin biodegradation conditions using ericoid mycorrhizal and white rot fungal species
In the search for methods to biodegrade recalcitrant compounds, the use of saprotrophic fungi and white rot fungi, in particular belonging to the phylum Basidiomycota, has gained interest. This group of fungi ... (Source: BMC Biotechnology)
Source: BMC Biotechnology - October 11, 2022 Category: Biotechnology Authors: Åke Stenholm, Mikael Hedeland and Curt E. Pettersson Tags: Research Source Type: research

Automatic identification of benign pigmented skin lesions from clinical images using deep convolutional neural network
We aimed to develop a computer-aided detection (CAD) system for accurate identification of benign pigmented skin lesions (PSLs) from images captured using a digital camera or a smart phone. (Source: BMC Biotechnology)
Source: BMC Biotechnology - October 10, 2022 Category: Biotechnology Authors: Hui Ding, Eejia Zhang, Fumin Fang, Xing Liu, Huiying Zheng, Hedan Yang, Yiping Ge, Yin Yang and Tong Lin Tags: Research Source Type: research

A new method for screening acute/chronic lymphocytic leukemia: dual-label time-resolved fluorescence immunoassay
Lymphocytic leukemia (LL) is a primary malignant tumor of hematopoietic tissue, which seriously affects the health of children and the elderly. The study aims to establish a new detection method for screening ... (Source: BMC Biotechnology)
Source: BMC Biotechnology - September 30, 2022 Category: Biotechnology Authors: Zhen Zhang, Jintao Zhang, Shanshan Dai and Hang Xu Tags: Research Source Type: research

Production of surfactant-stable keratinase from Bacillus cereus YQ15 and its application as detergent additive
With the growing concern for the environment, there are trends that bio-utilization of keratinous waste by keratinases could ease the heavy burden of keratinous waste from the poultry processing and leather in... (Source: BMC Biotechnology)
Source: BMC Biotechnology - September 8, 2022 Category: Biotechnology Authors: Rong-Xian Zhang, Zhong-Wei Wu, Hai-Yang Cui, Ying-Nan Chai, Cheng-Wei Hua, Peng Wang, Lan Li and Tian-You Yang Tags: Research Source Type: research

Efficient gene delivery into the embryonic chicken brain using neuron-specific promoters and in ovo electroporation
The chicken in ovo model is an attractive system to explore underlying mechanisms of neural and brain development, and it is important to develop effective genetic modification techniques that permit analyses ... (Source: BMC Biotechnology)
Source: BMC Biotechnology - September 2, 2022 Category: Biotechnology Authors: Kyung Min Jung, Kyung Je Park, Young Min Kim and Jae Yong Han Tags: Research Source Type: research

Metabolic engineering of energycane to hyperaccumulate lipids in vegetative biomass
The metabolic engineering of high-biomass crops for lipid production in their vegetative biomass has recently been proposed as a strategy to elevate energy density and lipid yields for biodiesel production. En... (Source: BMC Biotechnology)
Source: BMC Biotechnology - August 30, 2022 Category: Biotechnology Authors: Guangbin Luo, Viet Dang Cao, Baskaran Kannan, Hui Liu, John Shanklin and Fredy Altpeter Tags: Research Source Type: research

940 nm diode laser induced differentiation of human adipose derived stem cells to temporomandibular joint disc cells
Temporomandibular disorder (TMD) refers to a group of disorders that affect temporomandibular joint (TMJ) and its associated muscles with very limited treatment options. Stem cell research is emerging as one o... (Source: BMC Biotechnology)
Source: BMC Biotechnology - August 29, 2022 Category: Biotechnology Authors: Vesna Karic, Rahul Chandran and Heidi Abrahamse Tags: Research Source Type: research

Development of a human phage display-derived anti-PD-1 scFv antibody: an attractive tool for immune checkpoint therapy
The PD-1 checkpoint pathway plays a major role in tumor immune evasion and the development of the tumor microenvironment. Clinical studies show that therapeutic antibodies blocking the PD-1 pathway can restore... (Source: BMC Biotechnology)
Source: BMC Biotechnology - August 23, 2022 Category: Biotechnology Authors: Sepideh Safaei Ghaderi, Farhad Riazi-Rad, Elmira Safaie Qamsari, Salman Bagheri, Fatemeh Rahimi-Jamnani and Zahra Sharifzadeh Tags: Research Source Type: research

Generation of a recombinant antibody for sensitive detection of Pseudomonas aeruginosa
Pseudomonas aeruginosa (P. aeruginosa) is a major pathogen that causes nosocomial infections and often exhibits antibiotic resistance. Therefore, the development of an accurate method for detecting P. aeruginosa ... (Source: BMC Biotechnology)
Source: BMC Biotechnology - August 4, 2022 Category: Biotechnology Authors: Gyu-Min Lim, Joo-Kyung Kim, Eun-Jung Kim, Chang-Soo Lee, Wooseong Kim, Byung-Gee Kim and Hee-Jin Jeong Tags: Research Source Type: research

Generation of genome-edited dogs by somatic cell nuclear transfer
Canine cloning technology based on somatic cell nuclear transfer (SCNT) combined with genome-editing tools such as CRISPR-Cas9 can be used to correct pathogenic mutations in purebred dogs or to generate animal... (Source: BMC Biotechnology)
Source: BMC Biotechnology - July 13, 2022 Category: Biotechnology Authors: Dong-Ern Kim, Ji-Hye Lee, Kuk-Bin Ji, Kang-Sun Park, Tae-Young Kil, Okjae Koo and Min-Kyu Kim Tags: Research Source Type: research

Oleic acid based experimental evolution of Bacillus megaterium yielding an enhanced P450 BM3 variant
Unlike most other P450 cytochrome monooxygenases, CYP102A1 from Bacillus megaterium (BM3) is both soluble and fused to its redox partner forming a single polypeptide chain. Like other monooxygenases, it can catal... (Source: BMC Biotechnology)
Source: BMC Biotechnology - July 13, 2022 Category: Biotechnology Authors: Thierry Vincent, Bruno Gaillet and Alain Garnier Tags: Research Source Type: research

rocF affects the production of tetramethylpyrazine in fermented soybeans with Bacillus subtilis BJ3-2
Tetramethylpyrazine (TTMP) is a flavoring additive that significantly contributes to the formation of flavor compounds in soybean-based fermented foods. Over recent years, the application of TTMP in the food i... (Source: BMC Biotechnology)
Source: BMC Biotechnology - July 4, 2022 Category: Biotechnology Authors: Zhenli Liu, Yongjun Wu, Lincheng Zhang, Shuoqiu Tong, Jing Jin, Xian Gong and Jie Zhong Tags: Research Source Type: research

Development of an efficient veterinary rabies vaccine production process in the avian suspension cell line AGE1.CR.pIX
Mass vaccination of dogs as important rabies reservoir is proposed to most effectively reduce and eliminate rabies also in humans. However, a minimum coverage of 70% needs to be achieved for control of the dis... (Source: BMC Biotechnology)
Source: BMC Biotechnology - June 17, 2022 Category: Biotechnology Authors: Khaled Trabelsi, Meriem Ben Zakour, Ingo Jordan, Volker Sandig, Samia Rourou and Hela Kallel Tags: Research Source Type: research

Oil –water partition coefficient preparation and detection in the dihydroartemisinin self-emulsifying drug delivery system
The aim of the present study is to increase the solubility of dihydroartemisinin (DHA) using the self-emulsifying drug delivery system (SEDDS). (Source: BMC Biotechnology)
Source: BMC Biotechnology - May 27, 2022 Category: Biotechnology Authors: Yunhong Wang, Jingcai Chen, Yang Yang, Sijia Gao, Zhuzhu Wang, Yating Liu, Xiaomei Zhang, Lei Hua, Yanlei Guo and Yong Yang Tags: Research Source Type: research

αvβ3-targeted sEVs for efficient intracellular delivery of proteins using MFG-E8
Small extracellular vesicles (sEVs) are nanometer-sized membranous particles shed by many types of cells and can transfer a multitude of cargos between cells. Recent studies of sEVs have been focusing on their... (Source: BMC Biotechnology)
Source: BMC Biotechnology - May 21, 2022 Category: Biotechnology Authors: Junxin Mai, Kai Wang, Chenxuexuan Liu, Sheng Xiong and Qiuling Xie Tags: Research Source Type: research