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Elucidating the structural and functional prophecy of the Rv2326c gene, an ABC transporter of Mycobacterium tuberculosis H37Rv through computational approach
In this study, we found that Rv2326c protein might be working as an ABC transporter by which the drugs and other molecules are imported or exported into the bacterium. As a result, the current study provides a means to better understand its normal functioning and basic biology, which can help in the development of novel therapeutic targeting approaches for Rv2326c protein. (Source: Biotechnology and Applied Biochemistry)
Source: Biotechnology and Applied Biochemistry - August 24, 2023 Category: Biochemistry Authors: Priyanka Sharma, Ajit Kumar, Laxman S. Meena Tags: ORIGINAL ARTICLE Source Type: research

Anemonin inhibits sepsis ‐induced acute kidney injury via mitigating inflammation and oxidative stress
AbstractElevated inflammation and oxidative stress (OS) are the main pathologic features of acute kidney injury (AKI)-caused by sepsis. Here, we made an investigation into the protective effects of the natural compound Anemonin (ANE) on sepsis-induced AKI both in vitro and in vivo. Lipopolysaccharide (LPS) was applied to construct an in vitro AKI model in renal tubular epithelial cells, and the septic C57BL/6J mouse model was constructed via cecal ligation and puncture (CLP). Cell viability and apoptosis were detected. The levels of p53, Bax, Bcl2, Caspase3, Caspase8, Caspase9, AMP-activated protein kinase (AMPK), Sirt-1, ...
Source: Biotechnology and Applied Biochemistry - August 18, 2023 Category: Biochemistry Authors: Dan Liu, Li Li, Zengyan Li Tags: ORIGINAL ARTICLE Source Type: research

Mung bean as a potent emerging functional food having anticancer therapeutic potential: Mechanistic insight and recent updates
AbstractCancer is still a major challenge for humans. In recent years, researchers have focused on plant-based metabolites as a safe, efficient, alternative or combinatorial, as well as cost-effective preventive strategy against carcinogenesis. Mung bean is an important nutritious legume, and known for providing various health benefits due to various bioactive phytochemicals and easily digestible proteins. Regular intake of mung bean helps to regulate metabolism by affecting the growth and survival of good microbes in the host gut. Mung bean has also been reported to have anti-inflammatory, antioxidant, antiproliferative, ...
Source: Biotechnology and Applied Biochemistry - August 14, 2023 Category: Biochemistry Authors: Nirmala Sehrawat, Mukesh Yadav, Sunil Kumar, Ashwanti Devi, Rajbir Singh, Varruchi Sharma, Kuldeep Dhama, Jose M. Lorenzo, Anil Kumar Sharma Tags: MINI REVIEW Source Type: research

Correction to “G‐protein–coupled receptor 137 accelerates proliferation of urinary bladder cancer cells in vitro”
(Source: Biotechnology and Applied Biochemistry)
Source: Biotechnology and Applied Biochemistry - August 10, 2023 Category: Biochemistry Tags: CORRECTION Source Type: research

Retraction Statement: Lentivirus ‐mediated knockdown of Mphase phosphoprotein 8 inhibits proliferation of colon cancer cells
(Source: Biotechnology and Applied Biochemistry)
Source: Biotechnology and Applied Biochemistry - August 10, 2023 Category: Biochemistry Tags: RETRACTION Source Type: research

Retraction Statement: Long noncoding RNA linc ‐ITGB1 promotes cell migration and invasion in human breast cancer
(Source: Biotechnology and Applied Biochemistry)
Source: Biotechnology and Applied Biochemistry - August 10, 2023 Category: Biochemistry Tags: RETRACTION Source Type: research

Retraction Statement: Inhibition of GPR137 suppresses proliferation of medulloblastoma cells in vitro
(Source: Biotechnology and Applied Biochemistry)
Source: Biotechnology and Applied Biochemistry - August 10, 2023 Category: Biochemistry Tags: RETRACTION Source Type: research

Retraction Statement: Knockdown of GPR137 by RNAi inhibits pancreatic cancer cell growth and induces apoptosis
(Source: Biotechnology and Applied Biochemistry)
Source: Biotechnology and Applied Biochemistry - August 10, 2023 Category: Biochemistry Tags: RETRACTION Source Type: research

Retraction Statement: KLF8 is required for bladder cancer cell proliferation and migration
(Source: Biotechnology and Applied Biochemistry)
Source: Biotechnology and Applied Biochemistry - August 10, 2023 Category: Biochemistry Tags: RETRACTION Source Type: research

Retraction Statement: Inhibition of protein phosphatase 5 (PP5) suppresses survival and growth of colorectal cancer cells
(Source: Biotechnology and Applied Biochemistry)
Source: Biotechnology and Applied Biochemistry - August 10, 2023 Category: Biochemistry Tags: RETRACTION Source Type: research

Issue Information
(Source: Biotechnology and Applied Biochemistry)
Source: Biotechnology and Applied Biochemistry - August 10, 2023 Category: Biochemistry Tags: ISSUE INFORMATION Source Type: research

Correction to “G‐protein–coupled receptor 137 accelerates proliferation of urinary bladder cancer cells in vitro”
(Source: Biotechnology and Applied Biochemistry)
Source: Biotechnology and Applied Biochemistry - August 10, 2023 Category: Biochemistry Tags: CORRECTION Source Type: research