Biotechnology and Applied Biochemistry 
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Cell ‐free protein synthesis system: A new frontier for sustainable biotechnology‐based products
AbstractCell-free protein synthesis (CFPS) system is an innovative technology with a wide range of potential applications that could challenge current thinking and provide solutions to environmental and health issues. CFPS system has been demonstrated to be a successful way of producing biomolecules in a variety of applications, including the biomedical industry. Although there are still obstacles to overcome, its ease of use, versatility, and capacity for integration with other technologies open the door for it to continue serving as a vital instrument in synthetic biology research and industry. In this review, we mainly ...
Source: Biotechnology and Applied Biochemistry - September 21, 2023 Category: Biochemistry Authors: Anoth Maharjan,
Jung ‐Ho Park Tags: REVIEW ARTICLE Source Type: research
Tetrahydrobiopterin from cyanide ‐degrading bacterium Bacillus pumilus strain SVD06 induces apoptosis in human lung adenocarcinoma cell (A549)
AbstractTetrahydrobiopterin (BH4) is an essential biological cofactor and a derivative of pterin which is considered potent anticancer agents. In continuation of our previous study on the identification of BH4 from cyanide-degradingBacillus pumilus, the present study focuses on evaluating the anticancer properties of BH4 on A549, a human lung adenocarcinoma. Anticancer activity analysis shows that BH4 inhibited A549 cell growth after 24 h of incubation with 0.02 mg/mL. In acridine orange/ethidium bromide staining, BH4-treated A549 cells showed apoptotic morphology. BH4 treatment caused cell cycle arrest at G0/G1 phase c...
Source: Biotechnology and Applied Biochemistry - September 21, 2023 Category: Biochemistry Authors: Ramasamy Mahendran,
Sanjay Prasad Selvaraj,
Anand Raj Dhanapal,
Sabna Bhaskaran sarasa,
Beutline Malgija Mathias,
Bency Thankappan,
Daniel Raja Femil Selta,
Palanivel Naveen,
Rhenghachar Poorani,
Navaneethan Sundhar,
Mamatha M. Pillai,
Rajendra Tags: ORIGINAL ARTICLE Source Type: research
Preparation of silver nanoparticles by Osbeckia stellata aqueous extract via green synthesis approach: Characterization and assessment of their antioxidant, antidiabetic, cytotoxicity, and antibacterial properties
This study showed the spherical shape and crystalline nature of NPs. Zeta potential was used to determine the stability of Ag NPs. Biosynthesized Ag NPs showed significantly potent antioxidant, antidiabetic, and cytotoxicity activity. Ag NPs also showed effectiveness against gram-positive (Escherichia coli) and gram-negative (Staphylococcus aureus) bacteria in the antimicrobial activity study. The result concluded that these Ag NPs might be used in biomedical and pharmacological fields. (Source: Biotechnology and Applied Biochemistry)
Source: Biotechnology and Applied Biochemistry - September 13, 2023 Category: Biochemistry Authors: Tania Baishya,
Priya Das,
Gouhar Jahan Ashraf,
Tarun Kumar Dua,
Paramita Paul,
Gouranga Nandi,
Ankita Dutta,
Divya Limbu,
Anoop Kumar,
Manab Deb Adhikari,
Malay Bhattacharya,
Ranabir Sahu Tags: ORIGINAL ARTICLE Source Type: research
The anti ‐spermatogenic activity of nanoliposomes loaded with Heracleum persicum phenolic compounds in Balb/C mice
AbstractThere are various types of bioactivities that have been reported forHeracleum persicum species, such as antioxidant, anti-inflammatory, and cytotoxicity properties. In the current study, the bio-accessibility ofH. persicum bioactive compounds was improved by purifying its phenolic-enriched fractions (PEF) and encapsulating them into nanoliposomes to analyze its cytotoxic impacts on mice testicular tissue and their fertility status. Nano liposomalH. persicum PEF (NL-HPEF) was prepared by ultrasound-based encapsulation of HPEF and L-agranular lecithin mixture. The size, morphology, and stability of NL-HPEF were chara...
Source: Biotechnology and Applied Biochemistry - September 12, 2023 Category: Biochemistry Authors: Seyed Amirsajjad Alami,
Aryan Payrovnaziri,
Saeed Seghatoleslami,
Sara Faraji,
Fatemeh Rahimzadeh Bajgiran,
Mahsa Rastegar Moghaddam Poorbagher,
Negin Shafaei,
Ehsan Karimi,
Ehsan Oskoueian Tags: ORIGINAL ARTICLE Source Type: research
Current advances in Candida tropicalis: Yeast overview and biotechnological applications
AbstractCandida tropicalis is a nonconventional yeast with medical and industrial significance, belonging to the CTG clade. Recent advancements in whole-genome sequencing and genetic analysis revealed its close relation to other unconventional yeasts of biotechnological importance.C. tropicalis is known for its immense potential in synthesizing various valuable biomolecules such as ethanol, xylitol, biosurfactants, lipids, enzymes, α,ω-dicarboxylic acids, single-cell proteins, and more, making it an attractive target for biotechnological applications. This review provides an update onC. tropicalis biological characterist...
Source: Biotechnology and Applied Biochemistry - September 11, 2023 Category: Biochemistry Authors: Sarah de Souza Queiroz,
Fanny Machado Jofre,
Italo de Andrade Bianchini,
Tatiane da Silva Boaes,
Fernanda Weber Bordini,
Anuj Kumar Chandel,
Maria das Gra ças de Almeida Felipe Tags: REVIEW ARTICLE Source Type: research
New role of bacteriophages in medical oncology
AbstractTargeted treatment of cancer is one of the most paramount approaches in cancer treatment. Despite significant advances in cancer diagnosis and treatment methods, there are still significant limitations and disadvantages in the field, including high costs, toxicity, and unwanted damage to healthy cells. The phage display technique is an innovative method for designing carriers containing exogenic peptides with cancer diagnostic and therapeutic properties. Bacteriophages possess unique properties making them effective in cancer treatment. These characteristics include the small size enabling them to penetrate vessels...
Source: Biotechnology and Applied Biochemistry - September 6, 2023 Category: Biochemistry Authors: Mohammad Moradi,
Hadi Esmaeili Gouvarchin Ghaleh,
Masoumeh Bolandian,
Ruhollah Dorostkar Tags: MINI REVIEW Source Type: research
Analysis of the main bioactive compounds from Ocimum basilicum for their antimicrobial and antioxidant activity
This study is aimed to assess the antimicrobial and antioxidant activity of basil leaf extract prepared using ethanol, methanol, and water. The ethanol and methanol extract have all the phytochemicals (alkaloids, flavonoids, phenolic compounds, tannins, saponins, quinones, carbohydrates, and proteins) except steroids and terpenoids. In addition to steroids and terpenoids, tannin was also absent in the aqueous extract. Total phenolic and flavonoid content was high in ethanol and followed by methanol and aqueous extract. Similarly, ethanol and methanol extract showed strong antimicrobial activity against VRE and MTCC strains...
Source: Biotechnology and Applied Biochemistry - August 28, 2023 Category: Biochemistry Authors: Arockia Doss Susai Backiam,
Senbagam Duraisamy,
Palaniyandi Karuppaiya,
Senthilkumar Balakrishnan,
Aswathy Sathyan,
Anbarasu Kumarasamy,
Amutha Raju Tags: ORIGINAL ARTICLE Source Type: research
