From evidence to clinical practice: Bridging the gap of new liver cancer therapies in Latin America
Ann Hepatol. 2023 Nov 30:101185. doi: 10.1016/j.aohep.2023.101185. Online ahead of print.ABSTRACTThe most common primary liver tumors are hepatocellular carcinoma and cholangiocarcinoma. They constitute the sixth most common neoplasia and the third cause of cancer-related deaths worldwide. Although both tumors may share etiologic factors, diagnosis, prognostic factors, and treatments, they differ substantially in determining distinctive clinical management. In recent years, significant advances have been made in the management of these neoplasms, particularly in advanced stages. In this review, we focus on the most relevan...
Source: Annals of Hepatology - December 2, 2023 Category: Gastroenterology Authors: Federico Pi ñero Ezequiel Mauro Paola Casciato Alejandro Forner Source Type: research
Insulin resistance and metabolism-associated fatty liver disease: Pathways of action of hypoglycemic agents
Ann Hepatol. 2023 Nov 30:101182. doi: 10.1016/j.aohep.2023.101182. Online ahead of print.ABSTRACTMetabolism-associated fatty liver disease (MAFLD) is characterized by overweight/obesity, and the presence of type 2 diabetes mellitus is the most important criterion. We propose an independent disease perspective without exclusion criteria and with less heterogeneity and greater impact because, according to the National Health and Nutrition Survey (ENSANUT), in Mexico, 25% of adults over 60 years of age suffer from diabetes, and 96% of those over 50 years of age have abdominal obesity. Due to the impact of insulin resistance i...
Source: Annals of Hepatology - December 2, 2023 Category: Gastroenterology Authors: Maldonado-Rojas Andrea Del Carmen Zuarth-V ázquez Julia María Uribe M Barbero-Becerra Varenka J Source Type: research
From evidence to clinical practice: Bridging the gap of new liver cancer therapies in Latin America
Ann Hepatol. 2023 Nov 30:101185. doi: 10.1016/j.aohep.2023.101185. Online ahead of print.ABSTRACTThe most common primary liver tumors are hepatocellular carcinoma and cholangiocarcinoma. They constitute the sixth most common neoplasia and the third cause of cancer-related deaths worldwide. Although both tumors may share etiologic factors, diagnosis, prognostic factors, and treatments, they differ substantially in determining distinctive clinical management. In recent years, significant advances have been made in the management of these neoplasms, particularly in advanced stages. In this review, we focus on the most relevan...
Source: Annals of Hepatology - December 2, 2023 Category: Gastroenterology Authors: Federico Pi ñero Ezequiel Mauro Paola Casciato Alejandro Forner Source Type: research
Insulin resistance and metabolism-associated fatty liver disease: Pathways of action of hypoglycemic agents
Ann Hepatol. 2023 Nov 30:101182. doi: 10.1016/j.aohep.2023.101182. Online ahead of print.ABSTRACTMetabolism-associated fatty liver disease (MAFLD) is characterized by overweight/obesity, and the presence of type 2 diabetes mellitus is the most important criterion. We propose an independent disease perspective without exclusion criteria and with less heterogeneity and greater impact because, according to the National Health and Nutrition Survey (ENSANUT), in Mexico, 25% of adults over 60 years of age suffer from diabetes, and 96% of those over 50 years of age have abdominal obesity. Due to the impact of insulin resistance i...
Source: Annals of Hepatology - December 2, 2023 Category: Gastroenterology Authors: Maldonado-Rojas Andrea Del Carmen Zuarth-V ázquez Julia María Uribe M Barbero-Becerra Varenka J Source Type: research
A practical approach to the endoscopic management of biliary strictures after liver transplantation
Ann Hepatol. 2023 Nov 28:101186. doi: 10.1016/j.aohep.2023.101186. Online ahead of print.ABSTRACTBiliary tract complications are an important cause of morbidity and mortality after liver transplantation (LT) occurring in 5% to 25% of patients. The most common biliary complication in LT recipients are strictures representing approximately half of these biliary adverse events. Bile duct strictures can be divided into anastomotic biliary strictures (ABS) and non-anastomotic biliary strictures (NABS) depending on their location in the biliary tree, being ABS the most encountered type. Several risk factors identified in previou...
Source: Annals of Hepatology - November 30, 2023 Category: Gastroenterology Authors: Alex Bofill Andr és Cárdenas Source Type: research
Performance of eight predictive models for hepatocellular carcinoma recurrence after liver transplantation: a comparative study
CONCLUSIONS: The R3-AFP model, UCLA nomogram, AFP model, RETREAT, Combo MORAL, and Post-MORAL models demonstrated a moderate predictive capacity for hepatocellular carcinoma recurrence following transplantation. No significant differences were observed among these models in their ability to predict recurrence.PMID:38008358 | DOI:10.1016/j.aohep.2023.101184 (Source: Annals of Hepatology)
Source: Annals of Hepatology - November 26, 2023 Category: Gastroenterology Authors: Ajacio Bandeira de Mello Brand ão Santiago Rodriguez Cl áudio Augusto Marroni Alfeu de Medeiros Fleck Junior Matheus V Fernandes Marcos Mucenic Source Type: research
