Emerging biomolecules for practical theranostics of liver hepatocellular carcinoma
Ann Hepatol. 2023 Jul 13:101137. doi: 10.1016/j.aohep.2023.101137. Online ahead of print.ABSTRACTMost cases of hepatocellular carcinoma (HCC) are able to be diagnosed through regular surveillance in an identifiable patient population with chronic hepatitis B or cirrhosis. Nevertheless, 50% of global cases might present incidentally owing to symptomatic advanced-stage HCC after worsening of liver dysfunction. A systematic search based on PUBMED was performed to identify relevant outcomes, covering newer surveillance modalities including secretory proteins, DNA methylation, miRNAs, and genome sequencing analysis which propos...
Source: Annals of Hepatology - July 14, 2023 Category: Gastroenterology Authors: Miner Hu Xiaojun Xia Lichao Chen Yunpeng Jin Zhenhua Hu Shudong Xia Xudong Yao Source Type: research
Metformin ameliorates liver fibrosis induced by congestive hepatopathy via the mTOR/HIF-1 α signaling pathway
CONCLUSIONS: Metformin inhibits CH-induced liver fibrosis. Functionally, this beneficial effect may be the result of inhibition of HSC activation and of the mTOR/HIF-1α signaling pathway.PMID:37451514 | DOI:10.1016/j.aohep.2023.101135 (Source: Annals of Hepatology)
Source: Annals of Hepatology - July 14, 2023 Category: Gastroenterology Authors: Jing Yang Suxin Li Shengyan Liu Yuehui Zhang Dongqi Shen Peiju Wang Xiaowei Dang Source Type: research
Emerging biomolecules for practical theranostics of liver hepatocellular carcinoma
Ann Hepatol. 2023 Jul 12:101137. doi: 10.1016/j.aohep.2023.101137. Online ahead of print.ABSTRACTMost cases of hepatocellular carcinoma (HCC) are able to be diagnosed through regular surveillance in an identifiable patient population with chronic hepatitis B or cirrhosis. Nevertheless, 50% of global cases might present incidentally owing to symptomatic advanced-stage HCC after worsening of liver dysfunction. A systematic search based on PUBMED was performed to identify relevant outcomes, covering newer surveillance modalities including secretory proteins, DNA methylation, miRNAs, and genome sequencing analysis which propos...
Source: Annals of Hepatology - July 14, 2023 Category: Gastroenterology Authors: Miner Hu Xiaojun Xia Lichao Chen Yunpeng Jin Zhenhua Hu Shudong Xia Xudong Yao Source Type: research
Develop and validate a novel online AIHI-nomogram to predict severe liver inflammation in patients with autoimmune hepatitis
CONCLUSIONS: This novel AIHI-nomogram provided an excellent prediction of severe liver inflammation in AIH patients and could be used for the better management of AIH.PMID:37442347 | DOI:10.1016/j.aohep.2023.101134 (Source: Annals of Hepatology)
Source: Annals of Hepatology - July 13, 2023 Category: Gastroenterology Authors: Zhiyi Zhang Jian Wang Huali Wang Yiguang Li Li Zhu Yun Chen Jiacheng Liu Yilin Liu Yuxin Chen Shengxia Yin Xin Tong Xiaomin Yan Yongfeng Yang Chuanwu Zhu Jie Li Yuanwang Qiu Rui Huang Chao Wu Source Type: research
A multi-society Delphi consensus statement on new fatty liver disease nomenclature
CONCLUSIONS: The new nomenclature and diagnostic criteria are widely supported, non-stigmatising and can improve awareness and patient identification.PMID:37364816 | DOI:10.1016/j.aohep.2023.101133 (Source: Annals of Hepatology)
Source: Annals of Hepatology - June 26, 2023 Category: Gastroenterology Authors: Mary E Rinella Jeffrey V Lazarus Vlad Ratziu Sven M Francque Arun J Sanyal Fasiha Kanwal Diana Romero Manal F Abdelmalek Quentin M Anstee Juan Pablo Arab Marco Arrese Ramon Bataller Ulrich Beuers Jerome Boursier Elisabetta Bugianesi Christopher Byrne Grac Source Type: research
