Psoriasis and steatotic liver disease: Are PNPLA3 and TM6SF2 polymorphisms suitable for the hepato-dermal axis hypothesis?
CONCLUSIONS: MetS and T2DM confer higher odds for steatosis and advanced fibrosis in individuals with psoriasis. PNPLA3 G allele, but not TM6SF2 polymorphism, impacts a 5-fold odds of advanced liver fibrosis.PMID:38360269 | DOI:10.1016/j.aohep.2024.101477 (Source: Annals of Hepatology)
Source: Annals of Hepatology - February 15, 2024 Category: Gastroenterology Authors: Luciana Agoglia Ana Carolina Cardoso L ívia Barbosa Cec ília Schubert Xavier Lagalhard Victer Sueli Carneiro Paulo Henrique Condeixa de Fran ça Maria Chiara Chindamo Cristiane Alves Villela-Nogueira Source Type: research

Retinopathy as a predictive indicator for significant hepatic fibrosis according to T2DM status: A cross-sectional study based on the National Health and Nutrition Examination Survey Data
CONCLUSIONS: Retinopathy could serve as an independent predictor of significant hepatic fibrosis in T2DM population. Ophthalmologists are advised to closely monitor T2DM patients with retinopathy.PMID:38354949 | DOI:10.1016/j.aohep.2024.101478 (Source: Annals of Hepatology)
Source: Annals of Hepatology - February 14, 2024 Category: Gastroenterology Authors: Jinze Li Yi Xiang Jiahao Han Youfang Gao Ruiying Wang Zihe Dong Huihui Chen Ruixia Gao Chuan Liu Gao-Jun Teng Xiaolong Qi Source Type: research

Occult liver disease: a multinational perspective
Ann Hepatol. 2024 Feb 12:101480. doi: 10.1016/j.aohep.2024.101480. Online ahead of print.ABSTRACTOccult liver disease refers to the presence of unrecognized chronic liver disease and cirrhosis. Liver disease is currently the eleventh cause of death globally, representing 4% of all deaths in the world. Alcohol consumption is the leading cause of cirrhosis globally, accounting for approximately 60% of cases. The estimated global prevalence of non-alcoholic fatty liver disease (NAFLD) is 32.4% and has been steadily increasing over the last years. Viral hepatitis B and C accounted for 1.3 million deaths in 2020. Several studie...
Source: Annals of Hepatology - February 14, 2024 Category: Gastroenterology Authors: Paulina Vidal-Cevallos Nayelli Flores-Garc ía Norberto C Ch ávez-Tapia Naga P Chalasani Source Type: research

Retinopathy as a predictive indicator for significant hepatic fibrosis according to T2DM status: A cross-sectional study based on the National Health and Nutrition Examination Survey Data
CONCLUSIONS: Retinopathy could serve as an independent predictor of significant hepatic fibrosis in T2DM population. Ophthalmologists are advised to closely monitor T2DM patients with retinopathy.PMID:38354949 | DOI:10.1016/j.aohep.2024.101478 (Source: Annals of Hepatology)
Source: Annals of Hepatology - February 14, 2024 Category: Gastroenterology Authors: Jinze Li Yi Xiang Jiahao Han Youfang Gao Ruiying Wang Zihe Dong Huihui Chen Ruixia Gao Chuan Liu Gao-Jun Teng Xiaolong Qi Source Type: research

Occult liver disease: a multinational perspective
Ann Hepatol. 2024 Feb 12:101480. doi: 10.1016/j.aohep.2024.101480. Online ahead of print.ABSTRACTOccult liver disease refers to the presence of unrecognized chronic liver disease and cirrhosis. Liver disease is currently the eleventh cause of death globally, representing 4% of all deaths in the world. Alcohol consumption is the leading cause of cirrhosis globally, accounting for approximately 60% of cases. The estimated global prevalence of non-alcoholic fatty liver disease (NAFLD) is 32.4% and has been steadily increasing over the last years. Viral hepatitis B and C accounted for 1.3 million deaths in 2020. Several studie...
Source: Annals of Hepatology - February 14, 2024 Category: Gastroenterology Authors: Paulina Vidal-Cevallos Nayelli Flores-Garc ía Norberto C Ch ávez-Tapia Naga P Chalasani Source Type: research

LIVER FIBROSIS: more than meets the eye
Ann Hepatol. 2024 Feb 10:101479. doi: 10.1016/j.aohep.2024.101479. Online ahead of print.NO ABSTRACTPMID:38346642 | DOI:10.1016/j.aohep.2024.101479 (Source: Annals of Hepatology)
Source: Annals of Hepatology - February 12, 2024 Category: Gastroenterology Authors: Amedeo Lonardo Source Type: research

The 2023 Meeting of the Latin American Association for the Study of the Liver: A summary and looking ahead
Ann Hepatol. 2024 Feb 8:101476. doi: 10.1016/j.aohep.2024.101476. Online ahead of print.NO ABSTRACTPMID:38340792 | DOI:10.1016/j.aohep.2024.101476 (Source: Annals of Hepatology)
Source: Annals of Hepatology - February 10, 2024 Category: Gastroenterology Authors: Francisco Javier Valentin-Cortez Norberto Ch ávez-Tapia Source Type: research

ZBP1 promotes hepatocyte pyroptosis in acute liver injury by regulating the PGAM5/ROS pathway
CONCLUSIONS: ZBP1 promotes hepatocellular pyroptosis by modulating mitochondrial damage, which facilitates the extracellular release of ROS.PMID:38331384 | DOI:10.1016/j.aohep.2024.101475 (Source: Annals of Hepatology)
Source: Annals of Hepatology - February 8, 2024 Category: Gastroenterology Authors: Shengguang Yan Lina Yu Ziren Chen Dan Xie Zuli Huang Shi Ouyang Source Type: research

Impact of preoperative nonselective beta-blocker use on acute kidney injury after living donor liver transplantation: Propensity score analysis
CONCLUSIONS: Preoperative NSBB use was not associated with AKI after LDLT. Further studies are needed to validate our results.PMID:38331385 | DOI:10.1016/j.aohep.2024.101474 (Source: Annals of Hepatology)
Source: Annals of Hepatology - February 8, 2024 Category: Gastroenterology Authors: Hye-Won Jeong Jae Hwan Kim Sang-Bin Han Hye-Mee Kwon In-Gu Jun Jun-Gol Song Gyu-Sam Hwang Source Type: research

Lean non-alcoholic fatty liver disease and the risk of all-cause mortality: An updated meta-analysis
CONCLUSIONS: This meta-analysis revealed that lean NAFLD is associated with an approximately 1.6-fold increased mortality risk. Further studies are needed to unravel the existing but complex link between lean NAFLD and an increased risk of death.PMID:38278181 | DOI:10.1016/j.aohep.2024.101288 (Source: Annals of Hepatology)
Source: Annals of Hepatology - January 26, 2024 Category: Gastroenterology Authors: Wasit Wongtrakul Natthinee Charatcharoenwitthaya Phunchai Charatcharoenwitthaya Source Type: research

Societal costs and survival of patients with biopsy-verified non-alcoholic steatohepatitis: Danish nationwide register-based study
CONCLUSIONS: NASH, simple steatosis and cirrhosis are all associated with substantial costs for the individual and the society with excess healthcare costs and poorer labour market outcomes.PMID:38272183 | DOI:10.1016/j.aohep.2024.101285 (Source: Annals of Hepatology)
Source: Annals of Hepatology - January 25, 2024 Category: Gastroenterology Authors: Jan H åkon Rudolfsen Lise Lotte Gluud Henning Gr ønbæk Majken K Jensen Mogens Vyberg Jens Olsen Peter Bo Poulsen Nanna Hovels ø Nikolaj Ture Gregersen Anne Bloch Thomsen Peter Jepsen Source Type: research