Identification of polymorphic markers for germplasm conservation of three precious Chinese palace goldfish using whole-genome sequencing
This study provides reliable molecular tools and a basis for designing conservation and management programs in Chinese palace goldfish.PMID:38500412 | DOI:10.1111/age.13419 (Source: Animal Genetics)
Source: Animal Genetics - March 19, 2024 Category: Genetics & Stem Cells Authors: Yuwei Huang Aiying Cao Beiyuan Zhang Sen Li Chuan He Jian Gao Xiaojuan Cao Source Type: research
Unraveling genomic diversity and positive selection signatures of Qaidam cattle through whole-genome re-sequencing
Anim Genet. 2024 Mar 13. doi: 10.1111/age.13417. Online ahead of print.ABSTRACTQaidam cattle are a typical Chinese native breed inhabiting northwest China. They bear the characteristics of high cold and roughage tolerance, low-oxygen adaptability and good meat quality. To analyze the genetic diversity of Qaidam cattle, 60 samples were sequenced using whole-genome resequencing technology, along with 192 published sets of whole-genome sequencing data of Indian indicine cattle, Chinese indicine cattle, North Chinese cattle breeds, East Asian taurine cattle, Eurasian taurine cattle and European taurine cattle as controls. It w...
Source: Animal Genetics - March 14, 2024 Category: Genetics & Stem Cells Authors: Xudong Wei Shuang Li Huixuan Yan Shengmei Chen Ruizhe Li Weizhong Zhang Shengyu Chao Weixing Guo Wenhao Li Zulfiqar Ahmed Chuzhao Lei Zhijie Ma Source Type: research
Unraveling genomic diversity and positive selection signatures of Qaidam cattle through whole-genome re-sequencing
Anim Genet. 2024 Mar 13. doi: 10.1111/age.13417. Online ahead of print.ABSTRACTQaidam cattle are a typical Chinese native breed inhabiting northwest China. They bear the characteristics of high cold and roughage tolerance, low-oxygen adaptability and good meat quality. To analyze the genetic diversity of Qaidam cattle, 60 samples were sequenced using whole-genome resequencing technology, along with 192 published sets of whole-genome sequencing data of Indian indicine cattle, Chinese indicine cattle, North Chinese cattle breeds, East Asian taurine cattle, Eurasian taurine cattle and European taurine cattle as controls. It w...
Source: Animal Genetics - March 14, 2024 Category: Genetics & Stem Cells Authors: Xudong Wei Shuang Li Huixuan Yan Shengmei Chen Ruizhe Li Weizhong Zhang Shengyu Chao Weixing Guo Wenhao Li Zulfiqar Ahmed Chuzhao Lei Zhijie Ma Source Type: research
Unraveling genomic diversity and positive selection signatures of Qaidam cattle through whole-genome re-sequencing
Anim Genet. 2024 Mar 13. doi: 10.1111/age.13417. Online ahead of print.ABSTRACTQaidam cattle are a typical Chinese native breed inhabiting northwest China. They bear the characteristics of high cold and roughage tolerance, low-oxygen adaptability and good meat quality. To analyze the genetic diversity of Qaidam cattle, 60 samples were sequenced using whole-genome resequencing technology, along with 192 published sets of whole-genome sequencing data of Indian indicine cattle, Chinese indicine cattle, North Chinese cattle breeds, East Asian taurine cattle, Eurasian taurine cattle and European taurine cattle as controls. It w...
Source: Animal Genetics - March 14, 2024 Category: Genetics & Stem Cells Authors: Xudong Wei Shuang Li Huixuan Yan Shengmei Chen Ruizhe Li Weizhong Zhang Shengyu Chao Weixing Guo Wenhao Li Zulfiqar Ahmed Chuzhao Lei Zhijie Ma Source Type: research
Unraveling genomic diversity and positive selection signatures of Qaidam cattle through whole-genome re-sequencing
Anim Genet. 2024 Mar 13. doi: 10.1111/age.13417. Online ahead of print.ABSTRACTQaidam cattle are a typical Chinese native breed inhabiting northwest China. They bear the characteristics of high cold and roughage tolerance, low-oxygen adaptability and good meat quality. To analyze the genetic diversity of Qaidam cattle, 60 samples were sequenced using whole-genome resequencing technology, along with 192 published sets of whole-genome sequencing data of Indian indicine cattle, Chinese indicine cattle, North Chinese cattle breeds, East Asian taurine cattle, Eurasian taurine cattle and European taurine cattle as controls. It w...
Source: Animal Genetics - March 14, 2024 Category: Genetics & Stem Cells Authors: Xudong Wei Shuang Li Huixuan Yan Shengmei Chen Ruizhe Li Weizhong Zhang Shengyu Chao Weixing Guo Wenhao Li Zulfiqar Ahmed Chuzhao Lei Zhijie Ma Source Type: research
Genomic characterization of dryland adaptation in endangered Anxi cattle in China
In this study, we conducted a genomic comparison of 10 Anxi cattle genomes with those of five other global populations/breeds to assess genetic diversity and identify candidate genomic regions in Anxi cattle. Population structure and genetic diversity analyses revealed that Anxi cattle are part of the East Asian cattle clade, exhibiting higher genetic diversity than commercial breeds. Through selective sweep analysis, we identified specific genetic variations linked to the environmental adaptability of Anxi cattle. Notably, we identified several candidate genes, including CERS3 involved in regulating skin permeability and ...
Source: Animal Genetics - March 4, 2024 Category: Genetics & Stem Cells Authors: Yang Lyu Tingting Yao Zhefu Chen Ruiyao Huangfu Haijian Cheng Weidong Ma Xingshan Qi Fuqiang Li Ningbo Chen Chuzhao Lei Source Type: research
Genomic characterization of dryland adaptation in endangered Anxi cattle in China
In this study, we conducted a genomic comparison of 10 Anxi cattle genomes with those of five other global populations/breeds to assess genetic diversity and identify candidate genomic regions in Anxi cattle. Population structure and genetic diversity analyses revealed that Anxi cattle are part of the East Asian cattle clade, exhibiting higher genetic diversity than commercial breeds. Through selective sweep analysis, we identified specific genetic variations linked to the environmental adaptability of Anxi cattle. Notably, we identified several candidate genes, including CERS3 involved in regulating skin permeability and ...
Source: Animal Genetics - March 4, 2024 Category: Genetics & Stem Cells Authors: Yang Lyu Tingting Yao Zhefu Chen Ruiyao Huangfu Haijian Cheng Weidong Ma Xingshan Qi Fuqiang Li Ningbo Chen Chuzhao Lei Source Type: research
Genomic characterization of dryland adaptation in endangered Anxi cattle in China
In this study, we conducted a genomic comparison of 10 Anxi cattle genomes with those of five other global populations/breeds to assess genetic diversity and identify candidate genomic regions in Anxi cattle. Population structure and genetic diversity analyses revealed that Anxi cattle are part of the East Asian cattle clade, exhibiting higher genetic diversity than commercial breeds. Through selective sweep analysis, we identified specific genetic variations linked to the environmental adaptability of Anxi cattle. Notably, we identified several candidate genes, including CERS3 involved in regulating skin permeability and ...
Source: Animal Genetics - March 4, 2024 Category: Genetics & Stem Cells Authors: Yang Lyu Tingting Yao Zhefu Chen Ruiyao Huangfu Haijian Cheng Weidong Ma Xingshan Qi Fuqiang Li Ningbo Chen Chuzhao Lei Source Type: research
Genomic characterization of dryland adaptation in endangered Anxi cattle in China
In this study, we conducted a genomic comparison of 10 Anxi cattle genomes with those of five other global populations/breeds to assess genetic diversity and identify candidate genomic regions in Anxi cattle. Population structure and genetic diversity analyses revealed that Anxi cattle are part of the East Asian cattle clade, exhibiting higher genetic diversity than commercial breeds. Through selective sweep analysis, we identified specific genetic variations linked to the environmental adaptability of Anxi cattle. Notably, we identified several candidate genes, including CERS3 involved in regulating skin permeability and ...
Source: Animal Genetics - March 4, 2024 Category: Genetics & Stem Cells Authors: Yang Lyu Tingting Yao Zhefu Chen Ruiyao Huangfu Haijian Cheng Weidong Ma Xingshan Qi Fuqiang Li Ningbo Chen Chuzhao Lei Source Type: research
Genomic characterization of dryland adaptation in endangered Anxi cattle in China
In this study, we conducted a genomic comparison of 10 Anxi cattle genomes with those of five other global populations/breeds to assess genetic diversity and identify candidate genomic regions in Anxi cattle. Population structure and genetic diversity analyses revealed that Anxi cattle are part of the East Asian cattle clade, exhibiting higher genetic diversity than commercial breeds. Through selective sweep analysis, we identified specific genetic variations linked to the environmental adaptability of Anxi cattle. Notably, we identified several candidate genes, including CERS3 involved in regulating skin permeability and ...
Source: Animal Genetics - March 4, 2024 Category: Genetics & Stem Cells Authors: Yang Lyu Tingting Yao Zhefu Chen Ruiyao Huangfu Haijian Cheng Weidong Ma Xingshan Qi Fuqiang Li Ningbo Chen Chuzhao Lei Source Type: research
Genomic characterization of dryland adaptation in endangered Anxi cattle in China
In this study, we conducted a genomic comparison of 10 Anxi cattle genomes with those of five other global populations/breeds to assess genetic diversity and identify candidate genomic regions in Anxi cattle. Population structure and genetic diversity analyses revealed that Anxi cattle are part of the East Asian cattle clade, exhibiting higher genetic diversity than commercial breeds. Through selective sweep analysis, we identified specific genetic variations linked to the environmental adaptability of Anxi cattle. Notably, we identified several candidate genes, including CERS3 involved in regulating skin permeability and ...
Source: Animal Genetics - March 4, 2024 Category: Genetics & Stem Cells Authors: Yang Lyu Tingting Yao Zhefu Chen Ruiyao Huangfu Haijian Cheng Weidong Ma Xingshan Qi Fuqiang Li Ningbo Chen Chuzhao Lei Source Type: research
Genomic characterization of dryland adaptation in endangered Anxi cattle in China
In this study, we conducted a genomic comparison of 10 Anxi cattle genomes with those of five other global populations/breeds to assess genetic diversity and identify candidate genomic regions in Anxi cattle. Population structure and genetic diversity analyses revealed that Anxi cattle are part of the East Asian cattle clade, exhibiting higher genetic diversity than commercial breeds. Through selective sweep analysis, we identified specific genetic variations linked to the environmental adaptability of Anxi cattle. Notably, we identified several candidate genes, including CERS3 involved in regulating skin permeability and ...
Source: Animal Genetics - March 4, 2024 Category: Genetics & Stem Cells Authors: Yang Lyu Tingting Yao Zhefu Chen Ruiyao Huangfu Haijian Cheng Weidong Ma Xingshan Qi Fuqiang Li Ningbo Chen Chuzhao Lei Source Type: research
Genomic characterization of dryland adaptation in endangered Anxi cattle in China
In this study, we conducted a genomic comparison of 10 Anxi cattle genomes with those of five other global populations/breeds to assess genetic diversity and identify candidate genomic regions in Anxi cattle. Population structure and genetic diversity analyses revealed that Anxi cattle are part of the East Asian cattle clade, exhibiting higher genetic diversity than commercial breeds. Through selective sweep analysis, we identified specific genetic variations linked to the environmental adaptability of Anxi cattle. Notably, we identified several candidate genes, including CERS3 involved in regulating skin permeability and ...
Source: Animal Genetics - March 4, 2024 Category: Genetics & Stem Cells Authors: Yang Lyu Tingting Yao Zhefu Chen Ruiyao Huangfu Haijian Cheng Weidong Ma Xingshan Qi Fuqiang Li Ningbo Chen Chuzhao Lei Source Type: research
A de novo mutation in CACNA1A is associated with autosomal dominant bovine familial convulsions and ataxia in Angus cattle
The objective of this investigation was to identify hypothesized dominant genetic variation underlying the condition. Whole-genome sequencing was performed on the sire, six affected and seven unaffected paternal half-sibling calves and combined with data from 135 unrelated controls. The sire and five of the six affected calves were heterozygous for a nonsense variant (Chr7 g.12367906C>T, c.5073C>T, p.Arg1681*) in CACNA1A. The other affected calves (N = 8) were heterozygous for the variant but it was absent in the other unaffected calves (N = 7) and parents of the sire. This variant was also absent in sequence data fr...
Source: Animal Genetics - March 1, 2024 Category: Genetics & Stem Cells Authors: Rachel R Reith Jonathan E Beever Joe C Paschal Jason Banta Brian F Porter David J Steffen Thomas B Hairgrove Jessica L Petersen Source Type: research
A de novo mutation in CACNA1A is associated with autosomal dominant bovine familial convulsions and ataxia in Angus cattle
The objective of this investigation was to identify hypothesized dominant genetic variation underlying the condition. Whole-genome sequencing was performed on the sire, six affected and seven unaffected paternal half-sibling calves and combined with data from 135 unrelated controls. The sire and five of the six affected calves were heterozygous for a nonsense variant (Chr7 g.12367906C>T, c.5073C>T, p.Arg1681*) in CACNA1A. The other affected calves (N = 8) were heterozygous for the variant but it was absent in the other unaffected calves (N = 7) and parents of the sire. This variant was also absent in sequence data fr...
Source: Animal Genetics - March 1, 2024 Category: Genetics & Stem Cells Authors: Rachel R Reith Jonathan E Beever Joe C Paschal Jason Banta Brian F Porter David J Steffen Thomas B Hairgrove Jessica L Petersen Source Type: research
