Functional SNPs in SYISL promoter significantly affect muscle fiber density and muscle traits in pigs
In this study, three SNPs in exons and six SNPs within the promoter of pSYISL were identified. Association analysis showed that the two SNPs in exons are significantly associated with loin muscle area (p < 0.05); the six SNPs in the promoter that show complete linkage are significantly associated with live backfat thickness and live loin muscle area in American Large White pigs. Bioinformatics and luciferase reporter assays as well as in vitro binding experiments indicated that the mutation of SNP rs702045770 (g.539G>A) leads to the loss of YY1 binding to the promoter, thus affecting the expression level of pSYISL, a...
Source: Animal Genetics - October 26, 2023 Category: Genetics & Stem Cells Authors: Wei Lv Yaxin Peng Jingjing Hu Mingfei Zhu Yangcang Mao Litong Wang Guoshui Wang Zaiyan Xu Wangjun Wu Bo Zuo Source Type: research
Functional SNPs in SYISL promoter significantly affect muscle fiber density and muscle traits in pigs
In this study, three SNPs in exons and six SNPs within the promoter of pSYISL were identified. Association analysis showed that the two SNPs in exons are significantly associated with loin muscle area (p < 0.05); the six SNPs in the promoter that show complete linkage are significantly associated with live backfat thickness and live loin muscle area in American Large White pigs. Bioinformatics and luciferase reporter assays as well as in vitro binding experiments indicated that the mutation of SNP rs702045770 (g.539G>A) leads to the loss of YY1 binding to the promoter, thus affecting the expression level of pSYISL, a...
Source: Animal Genetics - October 26, 2023 Category: Genetics & Stem Cells Authors: Wei Lv Yaxin Peng Jingjing Hu Mingfei Zhu Yangcang Mao Litong Wang Guoshui Wang Zaiyan Xu Wangjun Wu Bo Zuo Source Type: research
Functional SNPs in SYISL promoter significantly affect muscle fiber density and muscle traits in pigs
In this study, three SNPs in exons and six SNPs within the promoter of pSYISL were identified. Association analysis showed that the two SNPs in exons are significantly associated with loin muscle area (p < 0.05); the six SNPs in the promoter that show complete linkage are significantly associated with live backfat thickness and live loin muscle area in American Large White pigs. Bioinformatics and luciferase reporter assays as well as in vitro binding experiments indicated that the mutation of SNP rs702045770 (g.539G>A) leads to the loss of YY1 binding to the promoter, thus affecting the expression level of pSYISL, a...
Source: Animal Genetics - October 26, 2023 Category: Genetics & Stem Cells Authors: Wei Lv Yaxin Peng Jingjing Hu Mingfei Zhu Yangcang Mao Litong Wang Guoshui Wang Zaiyan Xu Wangjun Wu Bo Zuo Source Type: research
Rapid genotyping of bovine MC1R gene c.296T & gt;C and c.310delG haplotypes using high-resolution melting analysis
Anim Genet. 2023 Oct 24. doi: 10.1111/age.13373. Online ahead of print.NO ABSTRACTPMID:37873887 | DOI:10.1111/age.13373 (Source: Animal Genetics)
Source: Animal Genetics - October 24, 2023 Category: Genetics & Stem Cells Authors: Rui Hong Yi Yan Changhong Zhu Fuyuan Zuo Gong-Wei Zhang Source Type: research
Rapid genotyping of bovine MC1R gene c.296T & gt;C and c.310delG haplotypes using high-resolution melting analysis
Anim Genet. 2023 Oct 24. doi: 10.1111/age.13373. Online ahead of print.NO ABSTRACTPMID:37873887 | DOI:10.1111/age.13373 (Source: Animal Genetics)
Source: Animal Genetics - October 24, 2023 Category: Genetics & Stem Cells Authors: Rui Hong Yi Yan Changhong Zhu Fuyuan Zuo Gong-Wei Zhang Source Type: research
The 4 bp deletion mutation in HOXD1 gene determines the polycerate trait in Chinese Sishui fur sheep
Anim Genet. 2023 Oct 17. doi: 10.1111/age.13369. Online ahead of print.NO ABSTRACTPMID:37846893 | DOI:10.1111/age.13369 (Source: Animal Genetics)
Source: Animal Genetics - October 17, 2023 Category: Genetics & Stem Cells Authors: Cheng Zhang Huan Zhang Tenggang Di Guan Wang Fengyi Gao Zhiqiang Li Ming Li Guangli Yang Source Type: research
The 4 bp deletion mutation in HOXD1 gene determines the polycerate trait in Chinese Sishui fur sheep
Anim Genet. 2023 Oct 17. doi: 10.1111/age.13369. Online ahead of print.NO ABSTRACTPMID:37846893 | DOI:10.1111/age.13369 (Source: Animal Genetics)
Source: Animal Genetics - October 17, 2023 Category: Genetics & Stem Cells Authors: Cheng Zhang Huan Zhang Tenggang Di Guan Wang Fengyi Gao Zhiqiang Li Ming Li Guangli Yang Source Type: research
The 4 bp deletion mutation in HOXD1 gene determines the polycerate trait in Chinese Sishui fur sheep
Anim Genet. 2023 Oct 17. doi: 10.1111/age.13369. Online ahead of print.NO ABSTRACTPMID:37846893 | DOI:10.1111/age.13369 (Source: Animal Genetics)
Source: Animal Genetics - October 17, 2023 Category: Genetics & Stem Cells Authors: Cheng Zhang Huan Zhang Tenggang Di Guan Wang Fengyi Gao Zhiqiang Li Ming Li Guangli Yang Source Type: research
The 4 bp deletion mutation in HOXD1 gene determines the polycerate trait in Chinese Sishui fur sheep
Anim Genet. 2023 Oct 17. doi: 10.1111/age.13369. Online ahead of print.NO ABSTRACTPMID:37846893 | DOI:10.1111/age.13369 (Source: Animal Genetics)
Source: Animal Genetics - October 17, 2023 Category: Genetics & Stem Cells Authors: Cheng Zhang Huan Zhang Tenggang Di Guan Wang Fengyi Gao Zhiqiang Li Ming Li Guangli Yang Source Type: research
The 4 bp deletion mutation in HOXD1 gene determines the polycerate trait in Chinese Sishui fur sheep
Anim Genet. 2023 Oct 17. doi: 10.1111/age.13369. Online ahead of print.NO ABSTRACTPMID:37846893 | DOI:10.1111/age.13369 (Source: Animal Genetics)
Source: Animal Genetics - October 17, 2023 Category: Genetics & Stem Cells Authors: Cheng Zhang Huan Zhang Tenggang Di Guan Wang Fengyi Gao Zhiqiang Li Ming Li Guangli Yang Source Type: research
The 4 bp deletion mutation in HOXD1 gene determines the polycerate trait in Chinese Sishui fur sheep
Anim Genet. 2023 Oct 17. doi: 10.1111/age.13369. Online ahead of print.NO ABSTRACTPMID:37846893 | DOI:10.1111/age.13369 (Source: Animal Genetics)
Source: Animal Genetics - October 17, 2023 Category: Genetics & Stem Cells Authors: Cheng Zhang Huan Zhang Tenggang Di Guan Wang Fengyi Gao Zhiqiang Li Ming Li Guangli Yang Source Type: research
Identification of potential biomarkers associated with meat tenderness in Hanwoo (Korean cattle): An expression quantitative trait loci analysis
Anim Genet. 2023 Oct 12. doi: 10.1111/age.13360. Online ahead of print.ABSTRACTMeat tenderness is considered the most important trait contributing to beef quality, level of consumer satisfaction, willingness to pay premium prices and industry profit. Genomic selection method would be helpful for genetic improvement of traits with low heritability and that are difficult to measure. The identification of core genes can aid genomic selection for complex traits with low heritability that are difficult to measure. We performed statistical analysis of associations between longissimus dorsi muscle tenderness and gene expression i...
Source: Animal Genetics - October 13, 2023 Category: Genetics & Stem Cells Authors: Yoonji Chung Sun Sik Jang Dong Hun Kang Yeong Kuk Kim Hyun Joo Kim Ki Yong Chung Inchul Choi Seung Hwan Lee Source Type: research
Identification of potential biomarkers associated with meat tenderness in Hanwoo (Korean cattle): An expression quantitative trait loci analysis
Anim Genet. 2023 Oct 12. doi: 10.1111/age.13360. Online ahead of print.ABSTRACTMeat tenderness is considered the most important trait contributing to beef quality, level of consumer satisfaction, willingness to pay premium prices and industry profit. Genomic selection method would be helpful for genetic improvement of traits with low heritability and that are difficult to measure. The identification of core genes can aid genomic selection for complex traits with low heritability that are difficult to measure. We performed statistical analysis of associations between longissimus dorsi muscle tenderness and gene expression i...
Source: Animal Genetics - October 13, 2023 Category: Genetics & Stem Cells Authors: Yoonji Chung Sun Sik Jang Dong Hun Kang Yeong Kuk Kim Hyun Joo Kim Ki Yong Chung Inchul Choi Seung Hwan Lee Source Type: research
Identification of potential biomarkers associated with meat tenderness in Hanwoo (Korean cattle): An expression quantitative trait loci analysis
Anim Genet. 2023 Oct 12. doi: 10.1111/age.13360. Online ahead of print.ABSTRACTMeat tenderness is considered the most important trait contributing to beef quality, level of consumer satisfaction, willingness to pay premium prices and industry profit. Genomic selection method would be helpful for genetic improvement of traits with low heritability and that are difficult to measure. The identification of core genes can aid genomic selection for complex traits with low heritability that are difficult to measure. We performed statistical analysis of associations between longissimus dorsi muscle tenderness and gene expression i...
Source: Animal Genetics - October 13, 2023 Category: Genetics & Stem Cells Authors: Yoonji Chung Sun Sik Jang Dong Hun Kang Yeong Kuk Kim Hyun Joo Kim Ki Yong Chung Inchul Choi Seung Hwan Lee Source Type: research
Identification of potential biomarkers associated with meat tenderness in Hanwoo (Korean cattle): An expression quantitative trait loci analysis
Anim Genet. 2023 Oct 12. doi: 10.1111/age.13360. Online ahead of print.ABSTRACTMeat tenderness is considered the most important trait contributing to beef quality, level of consumer satisfaction, willingness to pay premium prices and industry profit. Genomic selection method would be helpful for genetic improvement of traits with low heritability and that are difficult to measure. The identification of core genes can aid genomic selection for complex traits with low heritability that are difficult to measure. We performed statistical analysis of associations between longissimus dorsi muscle tenderness and gene expression i...
Source: Animal Genetics - October 13, 2023 Category: Genetics & Stem Cells Authors: Yoonji Chung Sun Sik Jang Dong Hun Kang Yeong Kuk Kim Hyun Joo Kim Ki Yong Chung Inchul Choi Seung Hwan Lee Source Type: research
