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Calculation of body surface area of corn snakes (Pantherophis guttatus) utilizing computed tomography
Am J Vet Res. 2023 Dec 4:1-4. doi: 10.2460/ajvr.23.09.0217. Online ahead of print.ABSTRACTOBJECTIVE: To determine the K-constant for body surface area calculation from body weight in corn snakes (Pantherophis guttatus) through the use of computed tomography (CT) measurements.ANIMALS: 12 adult corn snakes held by North Carolina State University for research purposes underwent CT between November 2022 and January 2023.METHODS: Each snake had a CT scan, physical examination, and body weight measurement. CT images were uploaded into software able to perform 3-D reconstruction and measure body surface area. The species-specific...
Source: American Journal of Veterinary Research - November 30, 2023 Category: Veterinary Research Authors: Daria G Hinkle Nathan C Nelson Elizabeth G Duke Tara M Harrison Source Type: research

A proposed rescue transesophageal echocardiographic protocol for anesthetized dogs
Am J Vet Res. 2023 Dec 4:1-8. doi: 10.2460/ajvr.23.07.0176. Online ahead of print.ABSTRACTOBJECTIVE: To describe the acquisition and pitfalls of a 3-view transesophageal echocardiography (TEE) protocol in anesthetized, dorsally recumbent dogs.ANIMALS: 8 beagles, 1 to 2 years old, 7.4 to 11.2 kg.METHODS: Dogs were anesthetized, mechanically ventilated, and placed in dorsal recumbency. A TEE probe was advanced, and 3 views were performed: midesophageal 4-chamber and long axis (ME 4C and ME LAX) and caudal esophageal short axis (CE SAX) at the level of the papillary muscles. Probe insertion depth, flexion, omniplane angle, an...
Source: American Journal of Veterinary Research - November 30, 2023 Category: Veterinary Research Authors: Manuel Martin-Flores Cheyenne J Cannarozzo Joaquin D Araos Andrew P Notarianni Felipe Teran Mark Rishniw Luis Campoy Robin D Gleed Source Type: research

Platinum measurements in Dulbecco's phosphate-buffered saline are lower than in plasma and can be sampled with ultrafiltration probes in vitro
Am J Vet Res. 2023 Dec 4:1-8. doi: 10.2460/ajvr.23.09.0205. Online ahead of print.ABSTRACTOBJECTIVE: To compare the influence of fluid on carboplatin elution, and assess the feasibility of ultrafiltration (UF) probe sampling.SAMPLE: 20 samples of 5 mg carboplatin in 1.0 mL 30% poloxamer 407 eluting in Dulbecco's phosphate-buffered saline (DPBS) or canine plasma and 6 samples of UF probe sampling in 0.01 mg/mL carboplatin in DPBS or plasma.METHODS: Carboplatin-gel specimens in dialysis tubing (12- to 14-kDa pores) were placed in 100 mL of DPBS or canine plasma (37 °C and 600 rpm stirring) in a nonlidded and lidded experime...
Source: American Journal of Veterinary Research - November 29, 2023 Category: Veterinary Research Authors: Marije Risselada Robyn McCain Source Type: research

Comparison of three methods for nucleus pulposus volume measurement in rabbit lumbar spines: a preclinical model for measurement of the effectiveness of prophylactic intervertebral disk fenestration in dogs
Am J Vet Res. 2023 Dec 4:1-7. doi: 10.2460/ajvr.23.07.0165. Online ahead of print.ABSTRACTOBJECTIVE: Compare 3 methods of nucleus pulposus (NP) volume measurement using the rabbit lumbar spines as a preclinical model to determine the effectiveness of prophylactic intervertebral disk fenestration in dogs.ANIMALS: Twelve 9-month-old, skeletally mature female entire New Zealand White rabbits weighing between 3.5 to 4.5 kg.METHODS: NP volume measurements of dissected rabbit lumber spines between L1 and L6 were made and compared using gross measurements, reconstructed MRI images, and water volumetry based on Archimedes' princip...
Source: American Journal of Veterinary Research - November 29, 2023 Category: Veterinary Research Authors: Jason Hawkins James D Crowley Matthew H Pelletier William R Walsh Source Type: research