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Serum activities of complement 1q and antibodies to the virulence-associated protein A are lower in foals that develop rhodococcal pneumonia
Am J Vet Res. 2024 Jan 13:1-10. doi: 10.2460/ajvr.23.08.0180. Online ahead of print.ABSTRACTOBJECTIVE: To determine the effects of transfusion of Rhodococcus equi hyperimmune plasma (REHIP) on serum concentrations of complement component 1q (C1q) and to examine the association of serum C1q and anti-rhodococcal antibodies of newborn foals with subsequent development of rhodococcal pneumonia.ANIMALS/SAMPLES: Foals (n = 205) from 2 Thoroughbred breeding farms in New York transfused with REHIP between January 1, 2022, and December 1, 2022.PROCEDURES: Blood was collected immediately before transfusion with REHIP and again from ...
Source: American Journal of Veterinary Research - January 9, 2024 Category: Veterinary Research Authors: Alexandra B Bettencourt Danyelle Reiskind Patricia Flores-Ahlschwede Susanne K Kahn Jocelyne M Bray Emma G Villafone Scott Ahlschwede Angela I Bordin Noah D Cohen Source Type: research

Antibacterial activity of silver nanoparticles against Escherichia coli and methicillin-resistant Staphylococcus pseudintermedius is affected by incorporation into carriers for sustained release
Am J Vet Res. 2024 Jan 16:1-11. doi: 10.2460/ajvr.23.10.0229. Online ahead of print.ABSTRACTOBJECTIVE: To establish the lowest effective dose of commercially available nanoparticulate silver (AgNP) for antibacterial activity against Escherichia coli (E coli) and methicillin-resistant Staphylococcus pseudintermedius (MRSP), in vitro, and to establish the effect of incorporating AgNP into carriers for sustained release on this antibacterial activity.SAMPLES: Silver nanoparticle dispersion (0.02 mg/mL) composed of citrate-stabilized, spherical, 10 nm diameter nanoparticles in aqueous buffer.PROCEDURES: E coli and MRSP were tr...
Source: American Journal of Veterinary Research - January 9, 2024 Category: Veterinary Research Authors: Miriam G Bates Marije Risselada Daniela C Pe ña-Hernandez Kenitra Hendrix George E Moore Source Type: research

Antibacterial activity of silver nanoparticles against Escherichia coli and methicillin-resistant Staphylococcus pseudintermedius is affected by incorporation into carriers for sustained release
Am J Vet Res. 2024 Jan 13:1-11. doi: 10.2460/ajvr.23.10.0229. Online ahead of print.ABSTRACTOBJECTIVE: To establish the lowest effective dose of commercially available nanoparticulate silver (AgNP) for antibacterial activity against Escherichia coli (E coli) and methicillin-resistant Staphylococcus pseudintermedius (MRSP), in vitro, and to establish the effect of incorporating AgNP into carriers for sustained release on this antibacterial activity.SAMPLES: Silver nanoparticle dispersion (0.02 mg/mL) composed of citrate-stabilized, spherical, 10 nm diameter nanoparticles in aqueous buffer.PROCEDURES: E coli and MRSP were tr...
Source: American Journal of Veterinary Research - January 9, 2024 Category: Veterinary Research Authors: Miriam G Bates Marije Risselada Daniela C Pe ña-Hernandez Kenitra Hendrix George E Moore Source Type: research

Improving the safety of spinal fracture fixation in dogs
Am J Vet Res. 2023 Dec 18;85(1):ajvr.23.10.0245. doi: 10.2460/ajvr.23.10.0245.NO ABSTRACTPMID:38171087 | DOI:10.2460/ajvr.23.10.0245 (Source: American Journal of Veterinary Research)
Source: American Journal of Veterinary Research - January 3, 2024 Category: Veterinary Research Authors: Ronan A Mullins Helen A Graham Rory M Breathnach Simon J More Source Type: research

Animal rehabilitation: closing the gap by putting science into practice
Am J Vet Res. 2023 Dec 18;85(1):ajvr.23.11.0254. doi: 10.2460/ajvr.23.11.0254.NO ABSTRACTPMID:38171088 | DOI:10.2460/ajvr.23.11.0254 (Source: American Journal of Veterinary Research)
Source: American Journal of Veterinary Research - January 3, 2024 Category: Veterinary Research Authors: David E Anderson Source Type: research

Dose effect and duration of action of liposomal bupivacaine administered as a perineural analgesic in a reversible and adjustable frog-pressure model of equine lameness
Am J Vet Res. 2023 Oct 16;85(1):ajvr.23.06.0122. doi: 10.2460/ajvr.23.06.0122. Print 2024 Jan 1.ABSTRACTOBJECTIVE: To determine the dose effect of peri-neural liposomal bupivacaine (LB) in an induced forelimb lameness model.ANIMALS: 12 clinically normal adult horses.METHODS: A randomized cross-over design was performed with 1 limb receiving saline and the other LB: low dose (6), high dose (6). Lameness was induced in 1 forelimb using a frog-pressure model. In the lame limb, peri-neural injection of the palmar nerves at the proximal sesamoid bones was performed using saline, low dose LB (0.25 mg/kg) (LDLB), or high dose LB ...
Source: American Journal of Veterinary Research - January 3, 2024 Category: Veterinary Research Authors: Allison Dockery Brian Beasley Molly Goldberg Gabrielle Aguirre Valerie J Moorman Source Type: research

Evidence-based journal strategies for 2024
Am J Vet Res. 2023 Dec 22;85(1):ajvr.85.01.editorial. doi: 10.2460/ajvr.85.01.editorial.NO ABSTRACTPMID:38171096 | DOI:10.2460/ajvr.85.01.editorial (Source: American Journal of Veterinary Research)
Source: American Journal of Veterinary Research - January 3, 2024 Category: Veterinary Research Authors: Lisa A Fortier Source Type: research