American Journal of Veterinary Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Sidestream dark field imaging and biomarker evaluation reveal minimal significant changes to the microcirculation and glycocalyx in a canine hemorrhagic shock model
Am J Vet Res. 2023 Oct 9;84(12):ajvr.23.06.0134. doi: 10.2460/ajvr.23.06.0134. Print 2023 Dec 1.ABSTRACTOBJECTIVE: To investigate the effects of hemorrhagic shock and fresh whole blood resuscitation on the microcirculation and endothelial glycocalyx using sidestream dark field (SDF) imaging and plasma biomarkers.ANIMALS: 8 purpose-bred dogs.METHODS: Pressure-targeted hemorrhagic shock was induced in anesthetized dogs. SDF measurement of perfused boundary region and microcirculatory variables (RBC flow, total vessel density, and relative and absolute capillary blood volume), biomarker measurement (heparan sulfate, hyalurona...
Source: American Journal of Veterinary Research - December 2, 2023 Category: Veterinary Research Authors: Jenna H Cardillo Jordan D Tarbutton Julien Guillaumin Tracy L Webb Kelly E Hall Claire D Tucker Amanda Cavanagh Kristin M Zersen Source Type: research

The use of a linear versus curvilinear oscillating saw blade for femoral head and neck excision surgery in cats
Am J Vet Res. 2023 Oct 16;84(12):ajvr.23.08.0187. doi: 10.2460/ajvr.23.08.0187. Print 2023 Dec 1.ABSTRACTOBJECTIVE: To determine the effects of using either a linear or curvilinear oscillating, battery-powered saw blade on the extent of bone resection, bone fissure or fragmentation, soft tissue trauma, and surgical time for femoral head and neck excision (FHNE) in feline cadavers.ANIMALS: 18 feline cadavers.METHODS: Paired feline cadaveric femora were randomly assigned to either a 10 mm linear or 12 mm curvilinear blade for FHNE by 2 surgical residents. CT of each femur pre- and postoperatively were used to create 3D recon...
Source: American Journal of Veterinary Research - December 2, 2023 Category: Veterinary Research Authors: Marie J A V P Pantangco Wendy I Baltzer Jason G Makar QiCai J Hoon Source Type: research

Untargeted metabolomic profiling of dogs with myxomatous mitral valve disease and congestive heart failure shows metabolic differences associated with the presence of cardiac cachexia
Am J Vet Res. 2023 Oct 11;84(12):ajvr.23.07.0161. doi: 10.2460/ajvr.23.07.0161. Print 2023 Dec 1.ABSTRACTOBJECTIVE: To determine the effects of cardiac cachexia on the metabolomic profile in dogs with myxomatous mitral valve disease (MMVD).ANIMALS: 3 groups of dogs with MMVD enrolled between November 30, 2018, and April 7, 2022: (1) Dogs with congestive heart failure (CHF) and cachexia (CHF-cachexia group; n = 10); (2) dogs with CHF that had no cachexia (CHF-no cachexia group; n = 10); and (3) dogs with asymptomatic disease (American College of Veterinary Internal Medicine [ACVIM] Stage B2) with no cachexia (B2 group; n = ...
Source: American Journal of Veterinary Research - December 2, 2023 Category: Veterinary Research Authors: Lisa M Freeman John E Rush Emily T Karlin Source Type: research

2023-a year of sustained growth and success for your journals
Am J Vet Res. 2023 Nov 27;84(12):ajvr.23.12.editorial. doi: 10.2460/ajvr.23.12.editorial.NO ABSTRACTPMID:38041952 | DOI:10.2460/ajvr.23.12.editorial (Source: American Journal of Veterinary Research)
Source: American Journal of Veterinary Research - December 2, 2023 Category: Veterinary Research Authors: Lisa A Fortier Source Type: research

The dilutional volume of morphine and xylazine administered via caudal epidural catheter affects cranial spread of analgesia in healthy standing horses
Am J Vet Res. 2023 Oct 16;84(12):ajvr.23.07.0166. doi: 10.2460/ajvr.23.07.0166. Print 2023 Dec 1.ABSTRACTOBJECTIVE: To test the influence of increasing injectate volumes on the regional effects of xylazine and morphine epidural analgesia, with the hypothesis that increasing volume produces more cranial spread of analgesia as determined by thermal threshold (TT) testing.ANIMALS: 6 university-owned research/teaching horses (2 mares, 4 geldings) deemed healthy on physical examination and basic lameness evaluation, aged 6-19 years and weighing 420-560 kg, were used in this prospective, randomized, blinded, cross-over experimen...
Source: American Journal of Veterinary Research - December 2, 2023 Category: Veterinary Research Authors: Dario Floriano Emma Gorenberg Amanda Watkins Klaus Hopster Source Type: research

Anesthetic efficacy of dexmedetomidine-ketamine in eastern box turtles (Terrapene carolina carolina) is enhanced with the addition of midazolam and when administered in the forelimb versus the hindlimb
Am J Vet Res. 2023 Dec 5:1-9. doi: 10.2460/ajvr.23.10.0226. Online ahead of print.ABSTRACTOBJECTIVE: To compare dexmedetomidine-ketamine (DK; 0.1 and 10 mg/kg, respectively) with midazolam (M; 1.0 mg/kg) or 0.9% sodium chloride (S; 0.2 mL/kg) administered IM in the forelimb (F) or hindlimb (H) in eastern box turtles (Terrapene carolina carolina).ANIMALS: 20 clinically healthy, captive adult eastern box turtles.METHODS: In a randomized, blinded, complete crossover study with 1-week washout periods, turtles were administered each of 3 treatments: F-DKS, F-DKM, or H-DKM. Palpebral reflex, muscle tone, and withdrawal responses...
Source: American Journal of Veterinary Research - December 1, 2023 Category: Veterinary Research Authors: Ashlyn C Heniff Olivia A Petritz Rachel G Carpenter Gregory A Lewbart Julie A Balko Source Type: research

Sedation with dexmedetomidine decreases skin perfusion in cats
Am J Vet Res. 2023 Oct 16;84(12):ajvr.23.06.0137. doi: 10.2460/ajvr.23.06.0137. Print 2023 Dec 1.ABSTRACTOBJECTIVE: To evaluate skin perfusion in cats receiving dexmedetomidine compared to a placebo.ANIMALS: 9 healthy adult research cats.METHODS: A randomized, blinded, placebo-controlled study design was used. Two sites, the dorsal metatarsus (site: limb) and lateral flank (site: flank), were evaluated with laser speckle contrast imaging (LSCI) at baseline and following administration of dexmedetomidine (1, 3, or 5 mcg/kg, IV) or a placebo (0.9% saline, IV). Mean speckle contrast (MSC), a surrogate for perfusion, was obtai...
Source: American Journal of Veterinary Research - December 1, 2023 Category: Veterinary Research Authors: Danielle L Hollenbeck Bradley T Simon Elizabeth M Scallan Kelley M Thieman-Mankin David R Miller Andrew K Dunn Vanna M Dickerson Source Type: research

Photobiomodulation therapy in dogs undergoing TPLO after cranial cruciate ligament rupture shows promise but no statistically significant difference in a randomized trial
Am J Vet Res. 2023 Dec 5:1-8. doi: 10.2460/ajvr.23.06.0138. Online ahead of print.ABSTRACTOBJECTIVE: Effect of photobiomodulation therapy (PBMT) in patients with CCLR after TPLO surgery by measuring C-reactive protein (CRP), percentage weight bearing, lameness using a short form of a composite measure pain scale, evaluated by the clinician and owners, and surgical site infection.SAMPLE: 54 client-owned dogs with CCLR undergoing unilateral TPLO surgery were enrolled in this study between April 5, 2021, through April 10, 2022.METHODS: The study population was randomly assigned to either a treatment group receiving PMBT (24 d...
Source: American Journal of Veterinary Research - December 1, 2023 Category: Veterinary Research Authors: Oscar A Chavez Walter Renberg Natalia Cernicchiaro Source Type: research

A proposed rescue transesophageal echocardiographic protocol for anesthetized dogs
Am J Vet Res. 2023 Dec 4:1-8. doi: 10.2460/ajvr.23.07.0176. Online ahead of print.ABSTRACTOBJECTIVE: To describe the acquisition and pitfalls of a 3-view transesophageal echocardiography (TEE) protocol in anesthetized, dorsally recumbent dogs.ANIMALS: 8 beagles, 1 to 2 years old, 7.4 to 11.2 kg.METHODS: Dogs were anesthetized, mechanically ventilated, and placed in dorsal recumbency. A TEE probe was advanced, and 3 views were performed: midesophageal 4-chamber and long axis (ME 4C and ME LAX) and caudal esophageal short axis (CE SAX) at the level of the papillary muscles. Probe insertion depth, flexion, omniplane angle, an...
Source: American Journal of Veterinary Research - November 30, 2023 Category: Veterinary Research Authors: Manuel Martin-Flores Cheyenne J Cannarozzo Joaquin D Araos Andrew P Notarianni Felipe Teran Mark Rishniw Luis Campoy Robin D Gleed Source Type: research

Calculation of body surface area of corn snakes (Pantherophis guttatus) utilizing computed tomography
Am J Vet Res. 2023 Dec 4:1-4. doi: 10.2460/ajvr.23.09.0217. Online ahead of print.ABSTRACTOBJECTIVE: To determine the K-constant for body surface area calculation from body weight in corn snakes (Pantherophis guttatus) through the use of computed tomography (CT) measurements.ANIMALS: 12 adult corn snakes held by North Carolina State University for research purposes underwent CT between November 2022 and January 2023.METHODS: Each snake had a CT scan, physical examination, and body weight measurement. CT images were uploaded into software able to perform 3-D reconstruction and measure body surface area. The species-specific...
Source: American Journal of Veterinary Research - November 30, 2023 Category: Veterinary Research Authors: Daria G Hinkle Nathan C Nelson Elizabeth G Duke Tara M Harrison Source Type: research