Thrombodynamics of Microvascular Repairs: Effects of Antithrombotic Therapy on Platelets and Fibrin
Conclusions:
These findings show that platelets have a rapid, transient response, whereas fibrin has a slower, more sustained accrual in both arterial and venous anastomoses. Furthermore, inhibition of either coagulation or platelet aggregation can influence presumably non-targeted components of thrombosis in vascular repairs of both arteries and veins.
Clinical relevance:
Preventing replantation failure using antithrombotic therapies requires a better understanding of the effect of each pharmacologic compound on the various aspects of thrombogenesis. (Source: The Journal of Hand Surgery)
Source: The Journal of Hand Surgery - July 29, 2013 Category: Surgery Authors: Glenn Shi, David Meister, Roger A. Daley, Brian C. Cooley Tags: Scientific Articles Source Type: research
