Cardiac effects of loperamide overdose
3 out of 5 stars
Not your regular high: cardiac dysrhythmias caused by loperamide. Wightman RS et al. Clin Toxicol 2016 Jun;54:454-458
Abstract
Loperamide is an over-the-counter anti-diarrhea medication that is available without prescription under a variety of brand names including Imodium. In therapeutic doses, loperamide acts as a peripheral mu-opioid receptor agonist but doesn’t cross the blood-brain barrier (BBB). However, in massive overdose loperamide can enter the brain and cause central opioid toxicity, including altered mental status and respiratory.
Although previously loperamide was thought to have litt...
Source: The Poison Review - April 29, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical cardiac effects cardiogoxicity long QT loperamide overdose QRS interval qt interval Source Type: news
Should Ondansetron Be Used for Acute Gastroenteritis?
Discussion
Acute gastroenteritis (AGE) is a common illness worldwide and is “…defined as a decrease in the consistency of stools (loose or liquid) and/or an increase in the frequency of evacuations with or without fever or vomiting….” It is one of the most common reasons for seeking medical care and hospitalizations. In Europe, rotavirus and noroviruses are two of the most frequent viral agents causing AGE and Campylobacter and Salmonella are the most common bacterial AGE causes. For parasitic infections Giardia, and Crytosporidium are most common parasitic infections in Europe.
Recommendations for...
Source: PediatricEducation.org - August 24, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
loperamide, Imodium A-D, Anti-Diarrheal, TH Anti-Diarrheal, Diamode, Imodium, Kaopectate II, Imodium
Title: loperamide, Imodium A-D, Anti-Diarrheal, TH Anti-Diarrheal, Diamode, Imodium, Kaopectate II, ImodiumCategory: MedicationsCreated: 7/23/1998 12:00:00 AMLast Editorial Review: 2/24/2015 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - February 24, 2015 Category: Nutrition Source Type: news
'Your Blood Tested Positive for Ebola. I Am Sorry.'
This was originally published on GatesNotes.com
Once in a while, you read something that's so compelling, you want to share it with everyone you can. Dr. Ada Igonoh's story had that effect on me.
Dr. Igonoh is a physician in Lagos, Nigeria, where she helped care for Patrick Sawyer, the patient who introduced Ebola into Nigeria in July. After coming down with the deadly virus herself, she spent two harrowing weeks getting treatment in isolation wards.
When I met her at a conference in New Orleans last week, Dr. Igonoh handed me a written account of her experience. Even knowing she was going to be okay, I couldn't stop re...
Source: Healthy Living - The Huffington Post - November 16, 2014 Category: Consumer Health News Source Type: news
Psyllium as Effective as Loperamide for Fecal IncontinencePsyllium as Effective as Loperamide for Fecal Incontinence
Episodes of fecal incontinence can be nearly halved with either psyllium fiber or loperamide, a crossover placebo-controlled trial has shown. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 20, 2014 Category: Consumer Health News Tags: Internal Medicine News Source Type: news
Summary: International Kidney Cancer Symposium
Conclusions:
Ideal ischemia time is 20-25 minutes or less improves short and long term renal function. >25 minutes carried 5 year risk of new onset stage 4 CKD
No differences on GFR for cold vs. warm ischemia times
Preoperative GFR and the percent of kidney preserved was a better predictor of post op GFR.
No ischemia preserves renal function better than warm.
Longer cold ischemia times were equivalent to shorter warm ischemia times.
Quality and quantity of the remaining kidney is associated with ultimate renal function.
Robotics in RCC Surgery
Gennady Bratslavsky, MD
The...
Source: Kidney Cancer Association - December 15, 2011 Category: Urology & Nephrology Source Type: news
Summary: International Kidney Cancer Symposium
Conclusions:
Ideal ischemia time is 20-25 minutes or less improves short and long term renal function. >25 minutes carried 5 year risk of new onset stage 4 CKD
No differences on GFR for cold vs. warm ischemia times
Preoperative GFR and the percent of kidney preserved was a better predictor of post op GFR.
No ischemia preserves renal function better than warm.
Longer cold ischemia times were equivalent to shorter warm ischemia times.
Quality and quantity of the remaining kidney is associated with ultimate renal function.
Robotics in RCC Surgery
Gennady Bratslavsky, MD
The opening question ...
Source: Kidney Cancer Association - December 15, 2011 Category: Urology & Nephrology Source Type: news
