Effect of fibrinogen replacement therapy on bleeding outcomes and 1-year mortality in patients undergoing thoracic aortic surgery: a retrospective cohort study
ConclusionsThe results of this study indicate that 2 –3 g of fibrinogen replacement reduces the incidence of major bleeding in patients with hypofibrinogenemia during cardiopulmonary bypass in thoracic aortic surgery. (Source: Journal of Anesthesia)
Source: Journal of Anesthesia - February 1, 2023 Category: Anesthesiology Source Type: research
Acute obstetric coagulopathy during postpartum hemorrhage is caused by hyperfibrinolysis and dysfibrinogenemia: an observational cohort study
CONCLUSIONS: Clinically significant hemostatic impairment is uncommon during PPH, but a subgroup of women have a distinct and severe coagulopathy characterized by hyperfibrinolysis, low fibrinogen, and dysfibrinogenemia associated with poor fetal outcomes.PMID:36696216 | DOI:10.1016/j.jtha.2022.11.036 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - January 25, 2023 Category: Hematology Authors: Lucy de Lloyd Peter V Jenkins Sarah F Bell Nicola J Mutch Julia Freyer Martins Pereira Pilar M Badenes Donna James Anouk Ridgeway Leon Cohen Thomas Roberts Victoria Field Rachel E Collis Peter W Collins Source Type: research
A rare case of pancytopenia causing ‐ Sheehan's syndrome: Case report and literature review
We describe the case of a 58-year-old woman who was presented with pancytopenia and hypofibrinogenemia. Treatment with iron supplementation was not satisfactory. Physical findings and a history of a massive postpartum hemorrhage suggested Sheehan's syndrome(SS). After thyroxine and glucocorticoid replacement therapy, the blood cell count improved. SS is a rare etiology of hemocytopenia, of which hematologists need to be aware. We conclude that hormonal therapy can produce full hematological recovery. (Source: Clinical Case Reports)
Source: Clinical Case Reports - January 24, 2023 Category: General Medicine Authors: Xiao ‐Han Gao,
Yuan Wang,
Rui‐Cang Wang,
Jun ‐Yuan,
Jie Yang,
Xiao‐Xia Zhang,
Jie Li Tags: CASE REPORT Source Type: research
Effect of fibrinogen replacement therapy on bleeding outcomes and 1-year mortality in patients undergoing thoracic aortic surgery: a retrospective cohort study
ConclusionsThe results of this study indicate that 2 –3 g of fibrinogen replacement reduces the incidence of major bleeding in patients with hypofibrinogenemia during cardiopulmonary bypass in thoracic aortic surgery. (Source: Journal of Anesthesia)
Source: Journal of Anesthesia - January 23, 2023 Category: Anesthesiology Source Type: research
